Abstract
It will soon become common practice for cardiologists to use glycoprotein IIb/IIIa (GPIIb/IIIa) receptor antagonists as adjunctive therapy in patients undergoing percutaneous transluminal coronary angioplasty (PTCA) for acute myocardial infarction (MI), predicts Dr Eric Topol from the Cleveland Clinic, Ohio, US. His comments followed the presentation of the RAPPORT * study results, which showed that administering the GPIIb/IIIa receptor antagonist abciximab to patients undergoing PTCA for acute MI led to a 74% reduction in the composite endpoint of death, recurrent MI and repeat target vessel revascularisation, compared with placebo. The data were presented at the 19th Congress of the European Society of Cardiology [ Stockholm, Sweden; August 1997 ].
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* ReoPro in Acute Myocardial Infarction and Primary PTCA Organisation and Randomised Trial
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Higgins, G. Abciximab to become routine adjunct to PTCA in acute MI?. Inpharma Wkly. 1103, 11–12 (1997). https://doi.org/10.2165/00128413-199711030-00023
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DOI: https://doi.org/10.2165/00128413-199711030-00023