Abstract
A new series of anticancer agents are being investigated in the US following the isolation of combretastatin compounds from the South African Combretum caffrum tree. Synthetic analogues of combretastatin have shown significant cytotoxic activity in preliminary studies, and hopes are high for their clinical development as therapy for breast and ovarian cancer.
Rights and permissions
About this article
Cite this article
Higgins, G. South African tree yields potent microtubule inhibitor. Inpharma Wkly. 907, 11 (1993). https://doi.org/10.2165/00128413-199309070-00024
Published:
Issue Date:
DOI: https://doi.org/10.2165/00128413-199309070-00024