American Journal of Clinical Dermatology

, Volume 9, Issue 5, pp 279–284 | Cite as

Can We Define Acne as a Chronic Disease?

If So,How and When?
  • Harald P.M. GollnickEmail author
  • Andrew Y. Finlay
  • Neil Shear
  • on behalf of the Global Alliance to Improve Outcomes in Acne
Current Opinion


There is widespread misunderstanding of acne amongst both the medical and lay community, who often perceive the condition to be a simple, self-limited affliction of adolescents. Because many think that the disease “will go away on its own,” they do not feel an urgency to aggressively treat acne. However, very often the reality is that acne treatment can be quite difficult. Furthermore, acne can be a devastating disease for the patient, since it manifests on visible body parts and in children near puberty, who are vulnerable both socially and psychologically. Most typically, acne is not an acute disease but rather a condition that continuously changes in its distribution and severity. Usually, acne treatment is necessary for many months and sometimes years. Despite treatment, acne may cause scarring and associated negative psychological effects. It is important for both patients and physicians to be aware that very effective treatments are available. It is also important to realize that new studies have proven the benefit of maintenance therapy with topical retinoids; these agents can minimize the potential for relapse, which is part of the natural history of acne. This article reviews the evidence suggesting that acne is a chronic disease in at least a subset of individuals. The members of the Global Alliance to Improve Outcomes in Acne believe that acne should be recognized and investigated as a chronic disease. This will change expectations of clinical trial design and treatment and will highlight gaps in the knowledge of acne epidemiology. The result should be an improvement in patient outcomes.


Atopic Dermatitis Acne Maintenance Therapy Tazarotene Psychosocial Impact 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by an unrestricted educational grant from Galderma Laboratories, L.P. A grant for editorial assistance was supplied for this article by Galderma Laboratories, L.P., and was used to pay for the services of Valerie Sanders, a professional medical writer.

The Global Alliance to Improve Outcomes in Acne is an international committee of physicians and researchers in the field of acne. Membership: Harald Gollnick, MD, Chair; Diane Thiboutot, MD, Co-Chair; Diane Berson, MD; Biigitte Dreno, MD, PhD; Andrew Finlay, MD; James J. Leyden, MD; Alan R. Shalita, MD. Steering Committee: Vincenzo Bettoli, MD; Alejandro Cordero, MD; Chee Leok Goh, MD, MRCP, FRCP, FAMS; Maria Isabel Herane, MD; Sewon Kang, MD, MPH; Raj Kubba, MD; Alison Layton, MD; Yoshiki Miyachi, MD, PhD; Montserrat Perez, MD; Jaime Piquero-Martin, MD; Marcia Ramos-e-Silva, MD, PhD; Jo Ann See, MD; Neil Shear, MD; Vicente Torres Lozada, MD; John Wolf Jr, MD.

All three authors have acted as consultants to Galderma Laboratories, L.P. Professor Finlay has also acted as a consultant to York Pharma UK, Strakan, and Pierre Fabre, and the Department of Dermatology, University of Cardiff School of Medicine, Cardiff, Wales has received royalties for use of the Dermatology Life Quality Index.


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Copyright information

© Adis Data Information BV 2008

Authors and Affiliations

  • Harald P.M. Gollnick
    • 1
    Email author
  • Andrew Y. Finlay
    • 2
  • Neil Shear
    • 3
    • 4
  • on behalf of the Global Alliance to Improve Outcomes in Acne
  1. 1.Department of Dermatology and VenereologyOtto von Guericke UniversityMagdeburgGermany
  2. 2.Department of DermatologyUniversity of Cardiff School of MedicineCardiffWales
  3. 3.Department of Dermatology and Department of Medicine, Pediatrics and PharmacologyUniversity of Toronto Medical SchoolTorontoCanada
  4. 4.Department of DermatologySunnybrook Women’s College Health Sciences CenterTorontoCanada

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