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Topical Halobetasol Propionate in the Treatment of Plaque Psoriasis

A Review

Abstract

Halobetasol propionate (HP) 0.5% ointment and cream are class I topical corticosteroids. We review the efficacy and tolerability of HP for treatment of plaque psoriasis in the English language literature. The efficacy of HP ointment and cream is consistently superior to other super-potent topical corticosteroids. Local adverse events associated with topical HP are similar to those experienced with other super-potent corticosteroids. Combination therapy with calcipotriene (calcipotriol) and tazarotene appears to be superior to monotherapy with topical HP.

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No sources of funding were used to assist in the preparation of this manuscript. The authors have no conflicts of interest that are directly relevant to the content of this manuscript.

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Correspondence to Sylvia Hsu.

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Rivera, A.M., Hsu, S. Topical Halobetasol Propionate in the Treatment of Plaque Psoriasis. Am J Clin Dermatol 6, 311–316 (2005). https://doi.org/10.2165/00128071-200506050-00004

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Keywords

  • Psoriasis
  • Topical Corticosteroid
  • Plaque Psoriasis
  • Calcipotriol
  • Tazarotene