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Dapoxetine

LY 210448

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Table I
Table II

References

  1. Reid LR, Robertson DW, Thompson DC. Effects of stereochemistry on inhibition of the serotonin (5HT) uptake carrier by LY243917. FASEB Journal 4: A988, 28 Feb 1990

    Google Scholar 

  2. PPD Inc. PPD Acquires Lilly’s Patents for Dapoxetine; Adjusts Earnings Guidance for 2003. Media Release: 18 Dec 2003. Available from URL: http://www.ppdi.com

    Google Scholar 

  3. PPD Inc. PPD Amends Dapoxetine License Agreement with ALZA; Adjusts Financial Guidance for 2004. Media Release: 5 Jan 2004. Available from URL: http://www.ppdi.com

    Google Scholar 

  4. ALZA Corporation. New Drug Application Submitted for Dapoxetine for Premature Ejaculation. Media Release: 28 Dec 2004. Available from URL: http://www.alza.com

    Google Scholar 

  5. Ortho Urology. First Medication Developed To Treat Premature Ejaculation Demonstrates Improvement In Control, Satisfaction And Time. Media Release: 23 May 2005. Available from URL: http://www.ortho-mcneil.com

    Google Scholar 

  6. Franklin RB, Manzione BM. Metabolism and disposition of the serotonin reuptake inhibitor, LY210448 hydrochloride in mice, rats, and dogs. Pharmacologist 32: 174, No. 3, 1990

    Google Scholar 

  7. Franklin RB, Manzione BM, Wrighton SA. Metabolism of the serotonin-reuptake inhibitor, LY210448 in several animal species. Pharmacologist 33: 208, No. 3, 1991

    Google Scholar 

  8. Dresser M, Gidwani S, Gupta SK, et al. Pharmacokinetics of single and multiple escalating doses of dapoxetine in healthy volunteers. Clinical Pharmacology and Therapeutics 75: 32, No. 2, Feb 2004

  9. Desai D, Dresser M, Jazrawi RP, et al. Dapoxetine for the treatment of premature ejaculation: lack of interaction with ethanol. Journal of Urology 173 (Suppl.): 239, No. 4, Apr 2005

    Google Scholar 

  10. Desai D, Dresser M, Jazrawi RP, et al. Dapoxetine for the treatment of premature ejaculation: lack of interaction with PDE5 inhibitors. Journal of Urology 173 (Suppl.): 201, No. 4, Apr 2005

    Google Scholar 

  11. Althof SE, Kell S, Miloslavsky M, et al. Efficacy and tolerability of dapoxetine in the treatment of premature ejaculation. Journal of Urology 173 (Suppl.): 201–2, No. 4, Apr 2005

    Google Scholar 

  12. Chester A, Gengo PJ, Giuliano F, et al. Monoaminergic transporter binding and inhibition profile of dapoxetine, a medication for the treatment of premature ejaculation. Journal of Urology 173 (Suppl.): 239, No. 4, Apr 2005

    Google Scholar 

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Dapoxetine. Drugs R D 6, 307–311 (2005). https://doi.org/10.2165/00126839-200506050-00007

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