Skip to main content
SpringerLink
Log in

RS 8359

  • Adis R&D Profile
  • Published:
Drugs in R & D Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Plenker A, Pchler K, Sasahara K, et al. Pharmacokinetics and pharmacodynamics of the new reversible MAO-A inhibitor RS-8359. Eur J Clin Pharmacol 1997; 52 Suppl.: 170

    Google Scholar 

  2. Püchler K, Schaffler K, Plenker A. The comparative effects of single and multiple doses of RS-8359, moclobemide and placebo on psychomotor function in healthy subjects. Int Psychopharmacol 1997 Sep; 12 Suppl. 5: 17–23

    Article  Google Scholar 

  3. Puechler K, Plenker A, Volz H-P, et al. The safety and tolerability profile of a new RIMA antidepressant, RS-8359 in healthy subjects and depressed patients. Eur Neuropsychopharmacol 1996 Sep; 6 Suppl. 4: 66

    Google Scholar 

  4. Plenker A, Püchler K, Volz H-P. The effects of RS-8359 on cardiovascular function in healthy subjects and depressed patients. Int Clin Psychopharmacol 1997 Sep; 12 Suppl. 5: 25–9

    Article  Google Scholar 

  5. Püchler K, Plenker A, Volz H-P. Safety, tolerability and efficacy of the reversible monoamine oxidase inhibitor RS-8359 in early clinical trials. Int Clin Psychopharmacol 1997 Sep; 12 Suppl. 5: 31–6

    Article  Google Scholar 

  6. Kumagae Y, Muramoto K, Kaneko T, et al. Assessment of pharmacological effects and concentrations of RS-8359 on same rats bymicrodialysis. Jpn J Pharmacol 1994; 64 Suppl. 1: 224

    Google Scholar 

  7. Kumagae Y, Shiozawa T, Matsui Y, et al. Changes in monoamine metabolism during and after ischemia, and its inhibition by a type A monoamine oxidase inhibitor, RS-8359. Jpn J Pharmacol 1990; 52 Suppl. 1: 227

    Google Scholar 

  8. Kozuka M, Kobayashi K, Iwata N. Effects of RS-8359 on reduced local cerebral glucose utilization in the rat subjected to transient forebrain ischemia. Jpn J Pharmacol 1994 Apr; 64: 257–64

    Article  PubMed  CAS  Google Scholar 

  9. Kozuka M, Minakawa F, Iwata N. Ameliorative effects of RS-8359 on neurochemical changes in the ischemic brain of SHRs. Jpn J Pharmacol 1991; 55 Suppl. 1: 286

    Google Scholar 

  10. Miura H, Naoi M, Nakahara D, et al. Changes in monoamine levels in mouse brain elicited by forced-swimming stress, and the protective effect of a new monoamine oxidase inhibitor, RS-8359. J Neural Transm Gen Sect 1993; 94 No. 3: 175–87

    Article  PubMed  CAS  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

About this article

Cite this article

RS 8359. Drugs R&D 2, 63–65 (1999). https://doi.org/10.2165/00126839-199902010-00020

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00126839-199902010-00020

Keywords

Search

Navigation