Skip to main content
Log in

Pazinaclone

A 77000, DN 2327

  • Adis R&D Profile
  • Published:
Drugs in R & D Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Hussein Z, Mulford DJ, Bopp BA, et al. Differences in the stereoselective pharmacokinetics of pazinaclone (DN-2327), a new anxiolytic, and its active metabolite after intravenous and oral single doses to dogs. Drug Metab Dispos 1993 Sep–Oct; 21: 805–10

    PubMed  CAS  Google Scholar 

  2. Suzuki M, Uchiumi M, Murasaki M. A comparative study of the psychological effects of DN-2327, a partial benzodiazepine agonist, and alprazolam. Psychopharmacology 1995 Oct; 121 (4): 42–50

    Article  Google Scholar 

  3. Linden M, Hadler D, Hofmann S. Randomized, double-blind, placebo-controlled trial of the efficacy and tolerability of a new isoindoline derivative (DN-2327) in generalized anxiety. Hum Psychopharm 1997 Sep–Oct; 12: 445–52

    Article  CAS  Google Scholar 

  4. Hashimoto T, Hamada C, Wada T, et al. Comparative study on the behavioral and EEG changes induced by diazepam, buspirone and a novel anxioselective anxiolytic, DN-2327, in the cat. Neuropsychobiology 1992; 26 (1–2): 89–99

    Article  PubMed  CAS  Google Scholar 

  5. Wada T, Fukuda N. Discriminative stimulus properties of a new anxiolytic, DN-2327, in rats. Psychopharmacology 1993 Feb; 110: 280–6

    Article  PubMed  CAS  Google Scholar 

  6. Evans SM, Foltin RW, Levin FR, et al. Behavioral and subjective effects of DN-2327 (pazinaclone) and alprazolam in normal volunteers. Behav Pharmacol 1995 Mar; 6: 176–86

    Article  PubMed  CAS  Google Scholar 

  7. Dietrich B. Pharmaco EEG effects of S(+)DN-2327 enantiomer and DN-2327 racemate. Eur Neuropsychopharmacol 1996 Jun; 6 Suppl. 3: 179

    Article  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pazinaclone. Drugs R&D 2, 57–59 (1999). https://doi.org/10.2165/00126839-199902010-00018

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00126839-199902010-00018

Keywords

Navigation