References
Karam R, Marcello S, Brooks RR, et al. Azimilide dihydrocholoride, a novel antiarrhythmic agent. Am J Cardiol 1998; 81: 40–6
Black SC, Butterfield JL, Lucchesi BR. Protection against programmed electrical stimulation-induced ventricular tachycardia and sudden cardiac death by NE-10064, a class III antiarrhythmic drug. J Cardiovasc Pharmacol 1993; 22: 810–8
Fermini B, Jurkiewicz NK, Jow B, et al. Use-dependent effects of the class III antiarrhythmic agent NE-10064 (azimilide) on cardiac repolarization: block of delayed rectifier potassium and L-type calcium currents. J Cardiovasc Pharmacol 1995; 26: 259–71
Miller KE, Carpenter JF, Brooks RR. Beta-adrenergic effects of the class III antiarrhythmic agent NE-10064 in the isolated perfused guinea pig heart. FASEB J 1993; 7 Pt 1: A108
McIntosh MA, Tanira M, Pacini D, et al. Comparison of the cardiac electrophysiologic effects of NE-10064 with sotalol and E-4031 and their modification by simulated ischaemia. J Cardiovasc Pharmacol 1994; 23: 653–7
Miller KE, Decker GE, Brittain D, et al. The class III antiarrhythmic NE-10064 suppresses ouabain-induced arrhythmias in guinea pigs. Can J Physiol Pharmacol 1994; 72 Suppl. 1: 82
Busch AE, Malloy KJ, Varnum MD, et al. A slowly-activating potassium current IKs is the target for class III antiarrhythmic drug NE-10064. Circulation 1993; 88 Suppl. Pt 2: 231
Gintant GA. Paradoxical effect of combined administration of class III agents on the canine ventricular action potential. Circulation 1996; 94 Suppl.: 160
Brooks RR, Butterfield JL. The class III antiarrhythmic NE-10064 increases QTc interval with minor hemodynamic effects in anesthetized dogs. Can J Physiol Pharmacol 1994; 72 Suppl. 1: 79
Brooks RR, Carpenter JF, Maynard AE, et al. Efficacy of a novel class III antiarrhythmic agent NE-10064 against ischemia/ reperfusion arrhythmias in rats. FASEB J 1993; 7 (Pt 1): A97
Drexler AP, Micklas JM, Brooks RR. Effects of intravenously administered NE-10064 on programmed electrical stimulation- induced ventricular arrhythmias in anesthetized infarcted dogs. FASEB J 1993; 7 (Pt 1): A97
Nattel S, Liu L, St-Georges D. Effects of the novel antiarrhythmic agent azimilide on experimental atrial fibrillation and atrial electrophysiologic properties. Cardiovasc Res 1998; 37: 627–35
Lavine SJ, Prcevski P. Comparison of hemodynamic effects of 2 type III antiarrhythmic agents in dogs with chronic ischemic left ventricular dysfunction. J Investig Med 1996; 44: 211
Pritchett E, Page R, Connolly S, et al. Azimilide treatment of atrial fibrillation. Circulation 1998; 98 Suppl.: 633
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Azimilide. Drugs in R&D 1, 297–300 (1999). https://doi.org/10.2165/00126839-199901040-00003
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DOI: https://doi.org/10.2165/00126839-199901040-00003