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Costs and Benefits of Prevention and Disease Management

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Disease Management and Health Outcomes

Abstract

Prevention and long term disease management have been added relatively recently as ‘new’ components of a modern day total healthcare services system. The goal of primary prevention, which includes medical preventive services, lifestyle interventions and screening services, is to maintain a symptom- and disease-free population. Disease management is a systematic post-disease attempt to manage the consequences of a disease.

This article focuses on the costs and savings of prevention and treatment for 7 major diseases which accounted for nearly 80% of the deaths in the US in 1990: heart disease, cancer, diabetes, arthritis, chronic bronchitis, influenza and asthma. The potential impact of prevention and disease management on costs, including productivity, represents a significant return-on-investment to society. Differences in the allocation of direct resources, however, make it nearly impossible to find a single suitable cost measure for the relative cost-effectiveness comparisons of prevention, acute treatment of disease and long term disease management. The relevant question may not be so much the relative cost effectiveness or benefits of the components of healthcare, but the benefits that an integrated approach brings to a total healthcare delivery system.

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References

  1. Department of Health and Human Services, Office of Disease Prevention and Health Promotion, US Preventive Services Task Force. The Guide to Clinical Preventive Services. Baltimore (MD): Williams & Wilkins, 1989

    Google Scholar 

  2. Chu RC, Trapnell GR. Costs of insuring preventive care. Inquiry 1990; 27: 273–80

    PubMed  CAS  Google Scholar 

  3. Kottke TE, Solberg LI, Brekke ML, et al. Delivery rates for preventive services in 44 midwestern clinics. Mayo Clin Proc 1997; 72: 515–23

    Article  PubMed  CAS  Google Scholar 

  4. McGinnis JM, Foege WH. Actual causes of death in the United States. JAMA 1993; 270: 2207–12

    Article  PubMed  CAS  Google Scholar 

  5. Fries JF, Green LW, Levine S, et al. Health promotion and the compression of morbidity. Lancet 1989; I: 481–3

    Article  Google Scholar 

  6. Fries JF, Koop E, Beadle CE, et al. Reducing health care costs by reducing the need and demand for medical services. N Engl J Med 1993; 329: 321–5

    Article  PubMed  CAS  Google Scholar 

  7. Vita AJ, Terry RB, Hubert HB, et al. Aging, health risks, and cumulative disability. N Engl J Med 1998; 38: 1035–41

    Article  Google Scholar 

  8. Yen LT, Edington DW, Witting P. Associations between health risk appraisal scores and employee medical claims costs in a manufacturing company. Am J Health Promot 1991; 6(1): 46–54

    Article  PubMed  CAS  Google Scholar 

  9. Edington DW, Yen LT, Witting P. The financial impact of changes in personal health practices. J Occup Environ Med 1997; 39(11): 1037–46

    Article  PubMed  CAS  Google Scholar 

  10. Burton WN, Chen C, Schultz AB, et al. The economic costs associated with body mass index in a workplace. J Occup Environ Med 1998; 40(9): 786–92

    Article  PubMed  CAS  Google Scholar 

  11. Leigh JP, Markowitz SB, Fahs M, et al. Occupational injury and illness in the United States: estimates of costs, morbidity, and mortality. Arch Intern Med 1997; 157: 1557–68

    Article  PubMed  CAS  Google Scholar 

  12. Greenberg PE, Findelstein SN, Berndt ER, et al. Calculating return on investment from reducing workplace illness. Drug Benefit Trends 1998; 10(3): 44–7

    Google Scholar 

  13. Centers for Disease Control. Effectiveness in disease and injury prevention estimated national spending on prevention — United States. MMWR Morb Mortal Wkly Rep 1988; 41: 529–31

    Google Scholar 

  14. Brouwer WBF, Koopmanschap MA, Rutten FFH. Productivity costs measurement through quality of life? A response to the recommendation of the Washington panel. Health Econ 1997; 6: 253–9

    Article  PubMed  CAS  Google Scholar 

  15. Weinstein MC, Siegel JE, Gold MR, et al. Recommendations of the panel on cost-effectiveness in health and medicine. JAMA 1996; 276(15): 1253–8

    Article  PubMed  CAS  Google Scholar 

  16. Graham JD, Corso PS, Morris JM, et al. Evaluating the cost-effectiveness of clinical and public health measures. Annu Rev Public Health 1998; 19: 125–52

    Article  PubMed  CAS  Google Scholar 

  17. Russell LB, Gold MR, Siegel JE, et al. The role of cost-effectiveness analysis in health and medicine. JAMA 1996; 276(14): 1172–7

    Article  PubMed  CAS  Google Scholar 

  18. Siegel JE, Weinstein MC, Russell LB, et al. Recommendations for reporting cost-effectiveness analyses. JAMA 1996; 276(16): 1339–41

    Article  PubMed  CAS  Google Scholar 

  19. Azimi NA, Welch HG. The effectiveness of cost-effectiveness analysis in containing costs. J Gen Intern Med 1998; 13(10): 664–9

    Article  PubMed  CAS  Google Scholar 

  20. Cohen D. Health promotion and cost-effectiveness. Health Promot Int 1994; 9(4): 281–7

    Article  Google Scholar 

  21. Leutwyler K. The price of prevention. Sci Am 1995 Apr; 272: 124–9

    Article  PubMed  CAS  Google Scholar 

  22. Phillips KA, Holtgrave DR. Using cost-effectiveness/cost-benefit analysis to allocate health resources: a level playing field for prevention? Am J Prev Med 1997; 13(1): 18–25

    PubMed  CAS  Google Scholar 

  23. Weinstein MC. Economics of prevention. J Gen Intern Med 1990 Sep/Oct; 5(5 Suppl.): S89–S92

    Article  PubMed  CAS  Google Scholar 

  24. Ganiats TG. Prevention, policy, and paradox: what is the value of future health? Am J Prev Med 1997; 13(1): 12–7

    PubMed  CAS  Google Scholar 

  25. Bonneux L, Barendregt JJ, Nusselder WJ, et al. Preventing fatal diseases increases healthcare costs: cause elimination life table approach. BMJ 1998; 316: 26–9

    Article  PubMed  CAS  Google Scholar 

  26. Russell LB. The role of prevention in health reform. N Engl J Med 1993; 329(5): 352–4

    Article  PubMed  CAS  Google Scholar 

  27. Ries LAG, Kosary CL, Hankey BF, et al. SEER Cancer Statistics Review, 1973–1994. NIH Pub. No. 97-2789. Bethesda (MD): National Cancer Institute, 1997

    Google Scholar 

  28. Adams PF, Marano MA. Current Estimates From the National Health Interview, 1994. National Center for Health Statistics. Vital Health Stat 10 1995; (193): 81–108

    Google Scholar 

  29. Anonymous. Public health focus: physical activity and the prevention of coronary heart disease. MMWR Morb Mortal Wkly Rep 1993; 42 (35): 669-72

  30. American Heart Association. Heart and Stroke Statistical Update, 1996. Dallas (TX): American Heart Association, 1997

    Google Scholar 

  31. Shephard RJ. Current perspectives on the economics of fitness and sport with particular reference to worksite programmes. Sports Med 1989; 7: 286–309

    Article  PubMed  CAS  Google Scholar 

  32. Foote A, Erfurt JC. The benefit-to-cost ratio of worksite blood-pressure control programs. JAMA 1991; 265(10): 1283–6

    Article  PubMed  CAS  Google Scholar 

  33. Erfurt JC, Foote A, Heirich MA. The cost-effectiveness of work-site Wellness programs for hypertension control, weight loss, and smoking cessation. J Occup Med 1991; 33(9): 962–70

    PubMed  CAS  Google Scholar 

  34. Leutzinger J, Hunnicutt D, Richling D. Predicting the ratio of benefit to cost in a cardiovascular disease prevention program. Manag Employee Health Benefits 1995; 3(4): 1–10

    Google Scholar 

  35. Tosteson A, Weinstein M, Hunink MGM, et al. Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels. Circulation 1997; 95(1): 24–30

    Article  PubMed  CAS  Google Scholar 

  36. Pelletier KR. Clinical and cost outcomes of multifactorial, cardiovascular risk management interventions in worksites: a comprehensive review and analysis. J Occup Environ Med 1997; 39(12): 1154–69

    Article  PubMed  CAS  Google Scholar 

  37. Kupersmith J, Holmes-Rovner M, Hogan A, et al. Cost-effectiveness analysis in heart disease, part II: preventive therapies. Prog Cardiovasc Dis 1995; 37(4): 243–71

    Article  PubMed  CAS  Google Scholar 

  38. Hennekens CH, Dyken ML, Fuster V. Aspirin as a therapeutic agent in cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 1997; 96(8): 2751–3

    Article  PubMed  CAS  Google Scholar 

  39. Superko HR. Cost-effective treatment of coronary artery disease — the new imperative. Clin Cardiol 1996; 19(8): 650–5

    Article  PubMed  CAS  Google Scholar 

  40. Brass-Mynderse NJ. Disease management for chronic congestive heart failure. J Cardiovasc Nurs 1996; 11(1): 54–62

    PubMed  CAS  Google Scholar 

  41. American Cancer Society. Cancer facts and figures — 1997. Atlanta: American Cancer Society, 1997

    Google Scholar 

  42. Greenwald P, Kramer BS, Weed DL, editors. Cancer prevention and control. New York: Marcel Dekker, Inc., 1995

    Google Scholar 

  43. Schuette JL, Tucker TC, Brown ML, et al. The costs of cancer care in the United States: implications for action. Oncology 1995; 9(11 Suppl.): 19–22

    PubMed  CAS  Google Scholar 

  44. Bal DG, Foerster SB. Dietary strategies for cancer prevention. Cancer 1993; 72(3 Suppl.): 1005–10

    Article  PubMed  CAS  Google Scholar 

  45. Anonymous. Breast and cervical cancer surveillance, United States, 1973–1987. MMWR CDC Surveill Summ 1992; 41 (SS-2): 1-7

  46. Salzmann P, Kerlikowske K, Phillips K. Cost-effectiveness of extending screening mammography guidelines to include women 40 to 49 years of age. Ann Intern Med 1997; 127(11): 955–65

    PubMed  CAS  Google Scholar 

  47. Burton W, Hoy D. The economic benefit of a corporate-sponsored mammography program. Worksite Health 1996 Summer: 27-33

  48. Legorreta AP, Brooks RJ, Leibowitz AN, et al. Cost of breast cancer treatment. A 4-year longitudinal study. Arch Intern Med 1996; 156(19): 2197–201

    Article  PubMed  CAS  Google Scholar 

  49. Simon JB. Should all people over the age of 50 have regular fecal occult-blood tests? N Engl J Med 1998; 338(16): 1151–5

    PubMed  CAS  Google Scholar 

  50. Burton WN, Schneider WJ. The value of workplace cancer screening. Manag Healthcare 1997; Nov: 42-45, 52

  51. Kantrowitz W, Doyle J, Semeraro J, et al. Prostate cancer screening in a large corporation population. J Occup Environ Med 1995; 37(10): 1193–8

    Article  PubMed  CAS  Google Scholar 

  52. Coley CM, Barry MJ, Fleming C, et al. Early detection of prostate cancer. Part II: estimating the risks, benefits, and costs. American College of Physicians. Ann Intern Med 1997; 126(6): 468–79

    PubMed  CAS  Google Scholar 

  53. Lefevre M. Prostate cancer screening: more harm than good? Am Fam Physician 1998; 58(2): 432–8

    PubMed  CAS  Google Scholar 

  54. Sox CH, Dietrich AJ, Tosteson TD, et al. Periodic health examinations and the provision of cancer preventive services. Arch Fam Med 1997; 6(3): 223–30

    Article  PubMed  CAS  Google Scholar 

  55. Anonymous. Mortality trends for selected smoking-related cancers and breast cancer — United States, 1950–1990. MMWR Morb Mortal Wkly Rep 1993; 42 (44): 857-66

  56. Anonymous. Trends in the prevalence and incidence of self-reported diabetes mellitus — United States, 1980–1994. MMWR Morb Mortal Wkly Rep 1997; 46 (43): 1014-8

  57. Anonymous. Economic consequences of diabetes mellitus in the US in 1997. Diabetes Care 1998; 21 (2): 296-309

  58. Herman WH, Dasbach EJ, Songer TJ, et al. The cost-effectivenss of intensive therapy for diabetes mellitus. Endocrinol Metab Clin North Am 1997; 26(3): 679–94

    Article  PubMed  CAS  Google Scholar 

  59. Selby JV, Ray GT, Ahang D, et al. Excess costs of medical care for patients with diabetes in a managed care population. Diabetes Care 1997; 20(9): 1396–402

    Article  PubMed  CAS  Google Scholar 

  60. Franz MJ. Lifestyle modifications for diabetes management. Endocrinol Metab Clin North Am 1997; 26(3): 499–510

    Article  PubMed  CAS  Google Scholar 

  61. Manson JE, Speisberg A. Primary prevention of non-insulin-dependent diabetes mellitus. Am J Prev Med 1994; 10(3): 172–84

    PubMed  CAS  Google Scholar 

  62. Wallberg-Henriksson H, Rincon J, Zierath JR. Exercise in the management of non-insulin-dependent diabetes mellitus. Sports Med 1998; 25(1): 25–35

    Article  PubMed  CAS  Google Scholar 

  63. Shaper AG, Wannamethee SG, Walker M. Body weight: implications for the prevention of coronary heart disease, stroke, and diabetes mellitus in a cohort study of middle aged men. BMJ 1997; 314(7090): 1311–7

    Article  PubMed  CAS  Google Scholar 

  64. Burton WN, Connerty CM. Evaluation of a worksite-based patient education intervention targeted at employees with diabetes mellitus. J Occup Environ Med 1998; 40(8): 702–6

    Article  PubMed  CAS  Google Scholar 

  65. Mangan M. Diabetes self-management education programs in the Veterans Health Administration. Diabetes Educ 1997; 23(6): 687–92, 695

    Article  PubMed  CAS  Google Scholar 

  66. Anonymous. Arthritis prevalence and activity limitations — United States, 1990. MMWR Morb Mortal Wkly Rep 1994; 43 (24): 433-8

  67. Anonymous. Prevalence and impact of arthritis among women — United States, 1989–1991 MMWR Morb Mortal Wkly Rep 1995; 44 (17): 329-34

  68. Yelin E, Callahan LF. The economic cost and social and psychological impact of musculoskeletal conditions. Arthritis Rheum 1995; 38(10): 1351–62

    Article  PubMed  CAS  Google Scholar 

  69. Gabriel SE, Crowson CS, Campion ME, et al. Direct medical costs unique to people with arthritis. J Rheumatol 1997; 24(4): 719–25

    PubMed  CAS  Google Scholar 

  70. Lanes SF, Lanza LL, Radensky PW, et al. Resource utilization and cost of care for rheumatoid arthritis and osteoarthritis in a managed care setting. Arthritis Rheum 1997; 40(8): 1475–81

    Article  PubMed  CAS  Google Scholar 

  71. Prashker MJ, Meenan RF. The total costs of drug therapy for rheumatoid arthritis. A model based on costs of drug, monitoring, and toxicity. Arthritis Rheum 1995; 38(3): 318–25

    Article  PubMed  CAS  Google Scholar 

  72. Lorig KR, Mazonson PD, Holman HR. Evidence suggesting that health education for self-management in patients with chronic arthritis has sustained health benefits while reducing health care costs. Arthritis Rheum 1993; 36(4): 439–46

    Article  PubMed  CAS  Google Scholar 

  73. Weinberger M, Tierney WM, Cowper PA, et al. Cost-effectiveness of increased telephone contact for patients with osteoarthritis. Arthritis Rheum 1993; 36(2): 243–6

    Article  PubMed  CAS  Google Scholar 

  74. Vollmer WM, Osborne M, Buist AS. 20-year trends in the prevalence of asthma and chronic airflow obstruction in an HMO. Am J Respir Crit Care Med 1998; 157(4 Pt 1): 1079–84

    PubMed  CAS  Google Scholar 

  75. National Center for Health Statistics. Monitoring health care in America. Quarterly fact sheet. Spotlight on: lung disease [online]. Washington, DC: National Center for Health Statistics, 1996 Dec. Available from: URL: http://www.cdc.gov/nchswww/releases/96facts/96sheets/mhc11296.htm

    Google Scholar 

  76. National Heart, Lung and Blood Institute. Estimates of direct and indirect costs of lung disease, 1993. New York: American Lung Association, 1998

    Google Scholar 

  77. Gross NJ. Chronic obstructive pulmonary disease: current concepts and therapeutic approaches. Chest 1990; 97(2 Suppl.): 19S–23S

    PubMed  CAS  Google Scholar 

  78. Aboussouan LS. Acute exacerbations of chronic bronchitis. Postgrad Med 1996; 99(4): 89–90, 95-8, 101-2

    PubMed  CAS  Google Scholar 

  79. Haggerty MC, Stockdale-Woolley R, Nair S. Respi-Care: an innovative home care program for the patient with chronic obstructive pulmonary disease. Chest 1991; 100(3): 607–12

    Article  PubMed  CAS  Google Scholar 

  80. Clarke SW Chronic bronchitis in the 1990s: up-to-date treatment. Respiration 1991; 58 Suppl. 1: 43–6

    Article  PubMed  Google Scholar 

  81. Law M, Tang JL. An analysis of the effectiveness of interventions intended to help people stop smoking. Arch Intern Med 1993; 155: 1933–9

    Article  Google Scholar 

  82. Bertera RL, Oehl LK, Telepchak JM. Self-help versus group approaches in smoking cessation in the workplace: eighteen-month follow-up and cost analysis. Am J Health Promot 1991; 4(3): 187–91

    Google Scholar 

  83. Jeffery RW, Forster JL, French SA, et al. The healthy worker project: a worksite intervention for weight control and smoking cessation. Am J Health Promot 1993; 83(3): 395–401

    CAS  Google Scholar 

  84. Anonymous. Public health focus: effectiveness of smoking-control strategies — United States. MMWR Morb Mortal Wkly Rep 1992; 41 (35): 645-7, 653

  85. Belman MJ. Exercise in patients with chronic obstructive pulmonary disease. Thorax 1993; 48: 936–46

    Article  PubMed  CAS  Google Scholar 

  86. National Center for Health Statistics, National Health interview survey, selected years, 1970–1994. New York: American Lung Association, 1998

    Google Scholar 

  87. Anonymous. Prevention and control of influenza recommendations of the advisory committee on immunization practices. MMWR Morb Mortal Wkly Rep 1998; 47 (RR-6): 1-35

  88. McBean AM, Babish JD, Warren JL. The impact and cost of influenza in the elderly. Arch Intern Med 1993; 153(18): 2105–11

    Article  PubMed  CAS  Google Scholar 

  89. Mullooly JP, Bennett MD, Hornbrook MC, et al. Influenza vaccination programs for elderly persons: cost-effectiveness in a health maintenance organization. Ann Intern Med 1994; 12(12): 947–52

    Google Scholar 

  90. Nichol KL, Margolis KL, Wouremna J, et al. The efficacy and cost effectiveness of vaccination against influenza among elderly persons living in the community. N Engl J Med 1994; 331(12): 778–84

    Article  PubMed  CAS  Google Scholar 

  91. Nichol KL, Lind A, Margolis KL, et al. The effectiveness of vaccination against influenza in healthy, working adults. N Engl J Med 1995; 333(14): 889–93

    Article  PubMed  CAS  Google Scholar 

  92. Musich S, Adams L, Broder J, et al. Preliminary evaluation of worksite influenza vaccination program: the experience of the Progressive Corporation. Worksite Health 1996 Fall: 27-34

  93. Anonymous. Surveillance for Asthma — United States, 1960–1995. 1998; 47(SS-1): 1–27

  94. National Center for Health Statistics, National Health interview survey, 1982–1994. New York: American Lung Association, 1998

    Google Scholar 

  95. Weiss KB, Gergen PJ, Hodgson TA. An economic evaluation of asthma in the United States. N Engl J Med 1992; 326(13): 862–6

    Article  PubMed  CAS  Google Scholar 

  96. Smith DH, Malone DC, Lawson KA, et al. A national estimate of the economic costs of asthma. Am J Respir Crit Care Med 1997; 156(3 Pt 1): 787–93

    PubMed  CAS  Google Scholar 

  97. Mushinski M. Average hospital charges for asthma treatment: United States, 1995. Stat Bull Metrop Insur Co 1997; 78(2): 26–32

    PubMed  CAS  Google Scholar 

  98. Moore CM, Ahmed I, Mouallem R, et al. Care of asthma: allergy clinic versus emergency room. Ann Allergy Asthma Immunol 1997; 78(4): 373–80

    Article  PubMed  CAS  Google Scholar 

  99. Bolton MB, Tilley BC, Kuder J, et al. The cost and effectiveness of an education program for adults who have asthma. J Gen Intern Med 1991; 6(5): 401–7

    Article  PubMed  CAS  Google Scholar 

  100. Taitel MS, Kotses H, Bernstein IL, et al. A self-management program for adult asthma. Pt II: cost-benefit analysis. J Allergy Clin Immunol 1995; 95(3): 672–6

    Article  PubMed  CAS  Google Scholar 

  101. Homer CJ. Asthma disease management. N Engl J Med 1997; 337(20): 1461–3

    Article  PubMed  CAS  Google Scholar 

  102. Cockcroft DW, Kalra S. Outpatient asthma management. Med Clin North Am 1996; 80(4): 701–18

    Article  PubMed  CAS  Google Scholar 

  103. Mackinnon NJ, Flagstad MS, Peterson CR, et al. Disease management program for asthma: baseline assessment of resource use. Am J Health Syst Pharm 1996; 53(5): 535–41

    PubMed  CAS  Google Scholar 

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Correspondence to Dee W. Edington.

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About the Authors: Shirley A. Musich, Ph.D. is a data analyst at the Health Management Research Center at the University of Michigan, Ann Arbor, Michigan, USA. Her research interests are in studying the associations between participation in health promotion programmes and changes in health risks and medical costs.

Wayne N. Burton, M.D. is Vice President and Chief Medical Officer for BANK ONE Corporation. His research interest is in providing health services to a large and diverse employee population to maintain health and high levels of productivity.

Dee W. Edington, Ph.D. is a Professor of Kinesiology and Director of the Health Management Research Center at the University of Michigan. His research interests are in studying the precursors to disease and the impact of prevention programmes on healthcare utilisation and costs.

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Musich, S.A., Burton, W.N. & Edington, D.W. Costs and Benefits of Prevention and Disease Management. Dis-Manage-Health-Outcomes 5, 153–166 (1999). https://doi.org/10.2165/00115677-199905030-00004

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