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Atlizumab

Anti-IL-6 receptor antibody — Chugai, Anti-interleukin-6 receptor antibody — Chugai, MRA — Chugai

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Table I
Table II

References

  1. Nishimoto N, Yoshizaki K, Miyasaka N, et al. A multi-center, randomized, double-blind, placebo-controlled trial of humanized anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis. Arthritis Rheum 2002 Sep; 46Suppl.: 559

    Google Scholar 

  2. Choy EHS, Isenberg DA, Garrood T, et al. Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial. Arthritis Rheum 2002 Dec; 46: 3143–50

    Article  PubMed  CAS  Google Scholar 

  3. Maini R, Charisma Study Group. A double-blind, randomised, parallel group, controlled, dose ranging study of the safety, tolerability, pharmacokinetics and efficacy of repeat doses of MRA given alone or in combination with methotrexate in patients with rheumatoid arthritis. Ann Rheum Dis 2003 Jul; 62Suppl. 1: 64

    Google Scholar 

  4. Atreya R, Mudter J, Finotto S, et al. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo. Nat Med 2000 May; 6(5): 583–8

    Article  PubMed  CAS  Google Scholar 

  5. Nishimoto N, Sasai M, Shima Y, et al. Improvement in Castleman’s disease by humanized anti-interleukin-6 receptor antibody therapy. Blood 2000 Jan 1; 95(1): 56–61

    PubMed  CAS  Google Scholar 

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Atlizumab. BioDrugs 17, 369–372 (2003). https://doi.org/10.2165/00063030-200317050-00006

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  • DOI: https://doi.org/10.2165/00063030-200317050-00006

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