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Switch from Risperidone to Perospirone in Patients with Chronic Schizophrenia

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References

  1. Volavka J, Czobor P, Sheitman B, et al. Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. Am J Psychiatry 2002; 159: 255–62

    Article  PubMed  Google Scholar 

  2. Csernansky JG, Mahmoud R, Brenner R, et al. A comparison of risperidone and haloperidol for the prevention of relapse in patients with schizophrenia. N Engl J Med 2002; 346: 16–22

    Article  PubMed  CAS  Google Scholar 

  3. Fujita K, Kanemoto K. Switching from risperidone to perospirone in 33 patients with chronic schizophrenia. Jpn J Clin Psychopharmacol 2002; 5 ( Suppl. ): 375–82

    Google Scholar 

  4. Inada T, Yagi G, Miura S. Extrapyramidal symptom profiles in Japanese patients with schizophrenia treated with olanzapine or haloperidol. Schizophr Res 2002; 57: 227–38

    Article  PubMed  Google Scholar 

  5. Guy W, Cleary P, Bonato RR. The brief psychiatric rating scale. In: ECDEU assessment manual for psychopharmacology, revised. Maryland: US Department of Health, Education, and Welfare, US Government Printing Office, 1976: 158–69

  6. Schotte A, Bonaventure P, Janssen PFM, et al. In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: risperidone compared with antipsychotics hitherto used. Jpn J Pharmacol 1995; 69: 399–412

    Article  PubMed  CAS  Google Scholar 

  7. Hirose A, Kato T, Ohno Y, et al. Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions. Jpn J Pharma-col 1990; 53: 321–9

    Article  CAS  Google Scholar 

  8. Murasaki M, Koyama T, Machiyama Y, et al. Clinical evaluation of a new antipsychotic, perospirone HCl, on schizophrenia: a comparative double-blind study with haloperidol [in Japanese]. Rinsho Hyoka 1997; 24: 159–205

    Google Scholar 

  9. Kapur S, Remington G, Zipursky RB, et al. The D2 dopamine receptor occupancy of risperidone and its relationship to extra-pyramidal symptoms: a PET study. Life Sci 1995; 57: PL103–7

    Article  PubMed  CAS  Google Scholar 

  10. Farde L, Nyberg S, Oxenstierna G, et al. Positron emission tomography studies on D-2 and 5-HT2 receptor binding in Risperidone-treated schizophrenic patients. J Clin Psychopharmacol 1995; 15 Suppl. 1: 195–235

    Google Scholar 

  11. Lewis DA. Atypical antipsychotic medications and the retreatment of schizophrenia. Am J Psychiatry 2002; 159: 177–9

    Article  PubMed  Google Scholar 

  12. Huttunen M. The evolution of the serotonin-dopamine antagonist concept. J Clin Psychopharmacol 1995; 15(1 Suppl. 1): 4S–10S

    Article  PubMed  CAS  Google Scholar 

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Acknowledgements

The authors acknowledge the help of Miss Junko Shibata in accumulating relevant papers. This study was supported by Sumitomo Pharmaceuticals Co. Ltd.

The authors have no conflicts of interest directly relevant to the content of this study.

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Authors and Affiliations

  1. Department of Neurospychiatry, Koseikan Hospital, Nagoya, Aichi, Japan

    Kazuyuki Fujita

  2. Department of Neuropsychiatry, Fukuchi Clinic, Nagoya, Aichi, Japan

    Toshihiko Fukuchi & Shoji Yuasa

  3. Department of Neuropsychiatry, Aichi Medical University, 21 Yazako-Karimata, Nagakute, 480-1195, Aichi, Japan

    Eriko Inada, Yoko Tarao &  Kousuke Kanemoto

Authors
  1. Kazuyuki Fujita
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  2. Toshihiko Fukuchi
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  3. Shoji Yuasa
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  4. Eriko Inada
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  5. Yoko Tarao
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  6. Kousuke Kanemoto
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Corresponding author

Correspondence to Kousuke Kanemoto.

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Fujita, K., Fukuchi, T., Yuasa, S. et al. Switch from Risperidone to Perospirone in Patients with Chronic Schizophrenia. Clin. Drug Investig. 24, 295–299 (2004). https://doi.org/10.2165/00044011-200424050-00006

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  • DOI: https://doi.org/10.2165/00044011-200424050-00006

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