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Lyme Neuroborreliosis

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Abstract

Lyme disease, the multisystem infectious disease caused by the tick-borne spirochaete Borrelia burgdorferi, has been well characterised over the past quarter century. When it is disseminated, multiple organ systems can be involved, with prominent involvement of joints, heart and both the peripheral and central nervous systems. Diagnosis is based on clinical presentation, with serological confirmation of exposure, using a combination of ELISA and Western blot techniques. When central nervous system involvement is suspected, examination of spinal fluid is invaluable. Even when infection has disseminated, and has been present for extended periods of time, response to conventional antibacterial therapy is excellent in the vast majority of individuals.

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Authors and Affiliations

  1. Department of Neurology, North Shore University Hospital, Manhasset, New York, 11030, USA

    John J. Halperin

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  1. John J. Halperin
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Correspondence to John J. Halperin.

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Halperin, J.J. Lyme Neuroborreliosis. Mol Diag Ther 14, 257–266 (2000). https://doi.org/10.2165/00023210-200014040-00002

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  • DOI: https://doi.org/10.2165/00023210-200014040-00002

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