Skip to main content

Advertisement

SpringerLink
Log in

Clinical and Economic Aspects of Prophylaxis and Treatment of Pneumocystis carinii Pneumonia

  • Guest Editorial
  • Pneumocystis carinii Pneumonia
  • Published:
PharmacoEconomics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Phair J, Munoz A, Detels R. et al. The risk of Pneumocystis carinii pneumonia among men infected with HIV Type I: Multicenter AIDS Cohort Study Group. N Engl J Med 1990; 322: 161–5

    Article  PubMed  CAS  Google Scholar 

  2. US Public Health Service Task Force on Antipneumocystis Prophylaxis for Patients with Human Immunodeficiency VirusInfection. Recommendation for prophylaxis against Pneumocystis,carinii pneumonia for adults and adolescenls infectedwith human immunodeficiency virus. MMWR Morb Monal Wkly Rep 1992; 41-RR4; 1–11

  3. Hughes W, Leoung G, Kramer F, et al. Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazoleto treat Pneumocystis carinii pneumonia in patients with AIDS. N Engl J Med 1993: 328: 1521–7

    Article  PubMed  CAS  Google Scholar 

  4. Sattler FR, Frame P, Davis R, et al. Trimetrexate with leucovorin versus trimethoprim sulfamethoxazole for moderate to severe episodes of Pneumocystis carinii pneumoniain patients with AIDS: a prospective, controlled multicenter investigation of the AIDS Clinical Trials Group protocol 029/031. J Infect Dis 1994; 170; 165–72

    Article  PubMed  CAS  Google Scholar 

  5. Medina I, Mills J, Leoung G, et al. Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome: a controlled trial of trimethoprim–dapsone. N Engl J Med 1990; 323: 776–82

    Article  PubMed  CAS  Google Scholar 

  6. Black JR, Feinberg J, Murphy RL, et al. Clindamycin and primaquine as primary treatment for mild and moderately severe Pneumocystis carinii pneumonia in patients with AIDS. Eur J Clin Microbiol lnfect Dis 1991; 10: 204–7

    Article  CAS  Google Scholar 

  7. Safrin S, Sattler FR, Lee BL, et al. Dapsone as a single agent is suboptimal therapy for Pneumocystis carinii pneumonia. J Acquir Immune Defic Syndr 1991; 4: 244–9

    PubMed  CAS  Google Scholar 

  8. Conte Jr JE, Chernoff D, Feigal Jr DW, et al. Intravenous or inhaled pentamidine for treating Pneumocystis carinii pneumoniain AIDS: a randomized trial. Ann Intern Med 1990: 113: 203–9

    PubMed  Google Scholar 

  9. Smith D, Davis S, Nelson M, et al. Pneumocystis carinii pneumonia treated with eflornithine in AIDS patients resistant to conventional therapy. AIDS 1990: 4: 1019–21

    Article  PubMed  CAS  Google Scholar 

  10. Bozzette SA, Sattler FR, Chiu J, et al. A controlled trial of early adjunctive treatment with corticosteroid, for Pneumocystis carinii pneumonia in acquired immunodeficiency syndrome. N Engl J Med 1990; 323: 1451–7

    Article  PubMed  CAS  Google Scholar 

  11. Leoung GS, Feigal Jr DW, Montgomery AB, et al. Aerosolized pentamidine for prophylaxis against Pneumocystis carinii pneumonia in the San Francisco community prophylaxis trial. N Engl J Med 1990; 323: 769–75

    Article  PubMed  CAS  Google Scholar 

  12. Hirschel B, Lazzarin A, Chopard P, et al. A controlled study of inhaled pentamidine for primary prevention of Pneumocystis carinii pneumonia. N Engl J Med 1991; 324: 1079–83

    Article  PubMed  CAS  Google Scholar 

  13. Hardy WD, Feinberg J, Finkelstein DM, et al. A controlled trial of trimethoprim-sulfamethoxazole or aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome:AIDS Clinical Trial Groupprotocol 021. N Engl J Med 1992: 327: 1842–8

    Article  PubMed  CAS  Google Scholar 

  14. Schneider MME, Hoepelman AIM, Eeftinck Schattenkerk JKM, et al. A controlled trial of aerosolized pentamidine or trimethoprim-sulfamethoxazoIe as primary prophylaxis against Pneumocystis carinii pneumonia in patients with human immunodeficiency virus infection. N Engl J Med 1992; 327: 1836–41

    Article  PubMed  CAS  Google Scholar 

  15. Hughes WT, Kennedy W, Dugdale M, et al. Prevention of Pneumocystis carinii pneumonia in AIDS patients with weekly dapsone. Lancet 1990; 336: 1066

    Article  PubMed  CAS  Google Scholar 

  16. Castellano AR, Nenlcman MD. Cost and benefit of secondary prophylaxis for Pneumocystis carinii pneumonia. JAMA 1991: 266: 820–4

    Article  PubMed  CAS  Google Scholar 

  17. Freedberg KA, Tosteson ANA, Cohen CJ, et al. Primary prophylaxis for Pneumocystis carinii pneumonia in HIV–infected persons with CD4 counts below 200/mm): a cost–effectiveness analysis. J Acquir Immune Defic Syndr 1991; 4: 521–31

    PubMed  CAS  Google Scholar 

  18. Hoover DR, Saah AJ, Bacellar H, et al. Clinical manifestations of AIDS in the era of Pneumocystis prophylaxis. N Engl J Med 1993: 329: 1922–6

    Article  PubMed  CAS  Google Scholar 

  19. Nightingale S, Cameron D, Gordin F, et al. Two controlled trials of rifabutin prophylaxis against Mycobacterium avium complex infection in AIDS. N Engl J Med 1993: 329: 828–33

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Clinical Economics Research Unit, Section of General Internal Medicine and the Clinical AIDS Program, Department of Medicine and Thorndike Memorial Laboratory, Talbot 325, Boston City Hospital and Boston University School of Medicine, 82 East Concord Street, Boston, Massachusetts, MA 02118, USA

    Kenneth A. Freedberg

Authors
  1. Kenneth A. Freedberg
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Freedberg, K.A. Clinical and Economic Aspects of Prophylaxis and Treatment of Pneumocystis carinii Pneumonia. Pharmacoeconomics 7, 95–98 (1995). https://doi.org/10.2165/00019053-199507020-00001

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00019053-199507020-00001

Keywords

Search

Navigation