Skip to main content

Advertisement

Log in

Economic Evaluation of Drug Therapy

A Review of the Contingent Valuation Method

  • Review Article
  • Published:
PharmacoEconomics Aims and scope Submit manuscript

Summary

The aim of this paper is to review the use of the contingent valuation (CV) method in economic evaluation of drug therapy. With the CV method, willingness to pay for a project ‘treatment’ is measured with survey methods, which makes it possible to carry out traditional cost-benefit analysis. The CV method has been developed in environmental economics and is now the most commonly used method of measuring environmental benefits. Due to the limitations of existing methods, empirical applications are starting to appear in the health field as well. From the empirical applications with respect to drug treatment it is evident that it is possible to achieve acceptable response rates. The methodological problems encountered when measuring willingness to pay with survey methods are similar to the problems encountered when measuring utility and quality of life in cost-utility analysis. It is concluded that further studies with the CV method are necessary to further explore questions concerning the reliability and validity of the method in this field.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Åberg H, Tibblin G. Addition of non-pharmacological methods of treatment in patients on antihypertensive drugs: results of previous medication, laboratory tests and life quality. Journal of Internal Medicine 226: 39–46, 1989

    Article  PubMed  Google Scholar 

  • Acton JP. Evaluating public programs to save lives: the case of heart attacks, RAND Report R-950-RC, Santa Monica, 1973

  • Berger MC, Blomquist GC, Kenkel D, Tolley GS. Valuing changes in health risks: a comparison of alternative measures. Southern Economic Journal 53: 967–984, 1987

    Article  Google Scholar 

  • Bishop RC, Heberlein JA. Measuring values of extra market goods: are indirect measures biased? American Journal of Agricultural Economics 61: 926–930, 1979

    Article  Google Scholar 

  • Boadway RW. The welfare foundations of cost-benefit analysis. Economic Journal 84: 926–39, 1974

    Article  Google Scholar 

  • Boadway RW, Bruce N. Welfare economics, Basil Blackwell, Oxford, 1984

    Google Scholar 

  • Bohm P. Estimating demand for public goods: an experiment. European Economic Review 3: 111–130, 1972

    Article  Google Scholar 

  • Bowker JM, Stoll JR. Use of dichotomous choice nonmarket methods to value the whooping crane resource. American Journal of Agricultural Economics 70: 372–381, 1988

    Article  Google Scholar 

  • Boyle KJ, Bishop RC. Welfare measurements using contingent valuation: a comparison of techniques. American Journal of Agricultural Economics 70: 21–28, 1988

    Article  Google Scholar 

  • Boyle KJ, Bishop RC, Welsh MP. Starting point bias in contingent valuation bidding games. Land Economics 61: 188–194, 1985

    Article  Google Scholar 

  • Boyle MH, Torrance GW, Sinclair JC, Horwood SP. Economic evaluation of neonatal intensive care of very-low-birth-weight infants. New England Journal of Medicine 308: 1330–1337, 1983

    Article  PubMed  CAS  Google Scholar 

  • Brookshire DS, d’Arge RC, Schulze WD, Thayer MA. Experiments in valuing public goods. In Smith VK (Ed.) Advances in applied microeconomics, vol 1, pp. 143–172, JAI Press Inc, Connecticut, 1981

    Google Scholar 

  • Brookshire DS, Ives BC, Schulze WD. The valuation of aesthetic preferences. Journal of Environmental Economics and Management 3: 325–346, 1976

    Article  Google Scholar 

  • Brookshire DS, Randall A, Stoll JR. Valuing increments and decrements of natural resource service flows. American Journal of Agricultural Economics 62: 478–488, 1980

    Article  Google Scholar 

  • Brookshire DS, Thayer MA, Schulze WD, d’Arge RC. Valuing public goods: a comparison of survey and hedonic approaches. American Economic Review 72: 165–177, 1982

    Google Scholar 

  • Cameron TA. A new paradigm for valuing non-market goods using referendum data: maximum likelihood estimation by censored logistic regression. Journal of Environmental Economics and Management 13: 255–268, 1988

    Google Scholar 

  • Cameron TA, James MD. Estimating willingness to pay from survey data: an alternative pre-test-market evaluation procedure. Journal of Marketing Research 24: 389–395, 1987a

    Article  Google Scholar 

  • Cameron TA, James MD. Efficient estimation methods for ‘closed-ended’ contingent valuation surveys. Review of Economics and Statistics 69: 269–276, 1987b

    Article  Google Scholar 

  • Carson RT. Constructed markets. In Braden & Kolstad (Eds.) Measuring the demand for environmental quality, Elsevier/North Holland, Amsterdam, 1991

    Google Scholar 

  • Cicchetti CJ, Smith VK. Congestion, quality deterioration, and optimal use: wilderness recreation in the Spanish peaks primitive area. Social Science Research 2: 15–30, 1973

    Article  Google Scholar 

  • Cooper BS, Rice DP. The economic cost of illness revisited. Social Security Bulletin 39: 21–36, 1976

    PubMed  CAS  Google Scholar 

  • Cronin FJ. Valuing nonmarket goods through contingent markets, Report to the U.S. Environmental Protection Agency, Washington, 1982

    Google Scholar 

  • Cummings RG, Brookshire DS, Schulze WD. Valuing environmental goods, Rowman and Allanheld, New Jersey, 1986

    Google Scholar 

  • Darling AH. Measuring benefits generated by urban water parks. Land Economics 49: 22–34, 1973

    Article  Google Scholar 

  • Daubert JT, Young RA. Recreational demands for maintaining instream flows: a contingent valuation approach. American Journal of Agricultural Economics 63: 666–676, 1981

    Article  Google Scholar 

  • Davis RK. Recreation planning as an economic problem. Natural Resources Journal 3: 239–249, 1963

    Google Scholar 

  • Gegax D, Gerking S, Schulze WD. Perceived risk and the marginal value of safety, Working paper prepared for the U.S. Environmental Protection Agency, Washington, 1985

  • Greenley DA, Walsh AG, Young RA. Option value: empirical evidence from a case study of recreation and water quality. Quarterly Journal of Economics 95: 657–673, 1981

    Article  Google Scholar 

  • Hammack B, Brown Jr GM. Waterfowl and wetlands: toward bioeconomic analysis, The Johns Hopkins University Press for Resources for the Future, Baltimore, 1974

    Google Scholar 

  • Hanemann MW. A methodological and empirical study of the recreation benefits from water quality improvement, Ph.D. Dissertation, Harvard University, 1978

  • Hanemann MW. Welfare evaluations in contingent valuation experiments with discrete responses. American Journal of Agricultural Economics 66: 332–341, 1984

    Article  Google Scholar 

  • Hanemann MW. Willingness-to-pay and willingness-to-accept: how much do they differ? American Economic Review 81: 635–647, 1991

    Google Scholar 

  • Hicks JR. The four consumer’s surpluses. Review of Economic Studies 11: 31–41, 1941

    Article  Google Scholar 

  • Johannesson M. Economic evaluation of lipid lowering: a feasibility test of the contingent valuation approach. Health Policy 20: 309–320, 1992

    Article  PubMed  CAS  Google Scholar 

  • Johannesson M, Åberg H, Agreus L, Borgquist L, Jonsson B. Cost-benefit analysis of non-pharmacological treatment of hypertension. Journal of Internal Medicine 230: 307–312, 1991b

    Article  PubMed  CAS  Google Scholar 

  • Johannesson M, Jönsson B. Economic evaluation in health care: is there a role for cost-benefit analysis? Health Policy 17: 1–23, 1991a

    Article  PubMed  CAS  Google Scholar 

  • Johannesson M, Jönsson B. Cost-effectiveness analysis of hypertension treatment: a review of methodological Issues. Health Policy 19: 55–78, 1991b

    Article  PubMed  CAS  Google Scholar 

  • Johannesson M, Jönsson B, Borgquist L. Willingness to pay for antihypertensive therapy: results of a Swedish pilot study. Journal of Health Economics 10: 461–473, 1991a

    Article  PubMed  CAS  Google Scholar 

  • Johansson P, Kriström B. Asymmetric and symmetric discrete response models in contingent valuation experiments, Statistical Research Report 1988: 7, Umeå University, 1988

  • Johansson P-O. The economic theory and measurement of environmental benefits, Cambridge University Press, Cambridge, 1987

    Book  Google Scholar 

  • Johansson P-O. An introduction to modern welfare economics, Cambridge University Press, Cambridge, 1991

    Book  Google Scholar 

  • Johansson P-O, Kriström B, Maler KG. A note on welfare evaluations with discrete response data. American Journal of Agricultural Economics 71: 1054–1056, 1989

    Article  Google Scholar 

  • Jones-Lee MW. The value of life: an economic analysis, Martin Robertson, London, 1976

    Google Scholar 

  • Jones-Lee MW, Hammerton M, Philips PR. The value of safety: results of a national sample survey. Economic Journal 95: 49–72, 1985

    Article  Google Scholar 

  • Jönsson B. Cost-benefit analysis in public health and medical care, Liber, Lund, 1976

    Google Scholar 

  • Jönsson B, Björk S, Hofvendal S, Levin JE. Quality of life in angina pectoris: a Swedish randomized cross-over comparison between transiderm-nitro and long acting oral nitrates. In van Eimeren & Horisberger (Eds) Socioeconomic evaluation of drug therapy, Springer-Verlag, Berlin, Heidelberg, 1988

    Google Scholar 

  • Klarman HE, Francis JOS, Rosenthal G. Cost effectiveness analysis applied to the treatment of chronic renal disease. Medical Care 6: 48–54, 1968

    Article  Google Scholar 

  • Knetsch JL, Sinden JA. Willingness to pay and compensation demanded: experimental evidence of an unexpected disparity in measures of value. Quarterly Journal of Economics 98: 507–521, 1984

    Article  Google Scholar 

  • Kriström B. Discrete and continuous valuation questions: do they give different answers?, Department of Forest Economics, Working paper 90, Swedish University of Agricultural Sciences in Umeå, 1989

  • Kriström B. Valuing environmental benefits using the contingent valuation method: an econometric analysis, Umea Economic Studies No 219, University of Umeå, 1990a

  • Kriström B. A non-parametric approach to the estimation of welfare measures in discrete response valuation studies, Land Economics 66: 135–139, 1990b

    Article  Google Scholar 

  • Milon JW. Contingent valuation experiments for strategic behavior. Journal of Environmental Economics and Management 17: 293–308, 1989

    Article  Google Scholar 

  • Mishan EJ. Evaluation of life and limb: a theoretical approach. Journal of Political Economy 79: 687–705, 1971

    Article  Google Scholar 

  • Mitchell RC, Carson RT. An experiment in determining willingness to pay for national water quality improvements, Draft Report Prepared for the U.S. Environmental Protection Agency, Washington, 1981

  • Mitchell RC, Carson RT. Using surveys to value public goods, Resources for the Future, Washington, 1989

    Google Scholar 

  • Pearce DW, Dasgupta A. Cost-benefit analysis: theory and practice, Macmillan, London, 1971

    Google Scholar 

  • Randall A, Grunewald O, Pagoulatos A, Ausness R, Johnson S. Reclaiming coal surface mines in central appalachia: a case study of the benefits and costs. Land Economics 54: 472–489, 1978

    Article  Google Scholar 

  • Randall A, Ives BC, Eastman C. Bidding games for valuation of aesthetic environmental improvements. Journal of Environmental Economics and Management 1: 132–149, 1974

    Article  Google Scholar 

  • Ridker RG. Economic costs of air pollution, Praeger, New York, 1967

    Google Scholar 

  • Rowe RD, d’Arge RC, Brookshire DS. An experiment on the economic value of visibility. Journal of Environmental Economics and Management 7: 1–19, 1980

    Article  Google Scholar 

  • Scherr BA, Babb EM. Pricing public goods: an experiment with two proposed pricing systems. Public Choice 23: 35–48, 1975

    Article  Google Scholar 

  • Schulze WD, Cummings RG, Brookshire DS, Thayer MA, Whitworth R, et al. Methods development in measuring benefits of environmental improvements: experimental approaches to valuing environmental commodities, Vol 2, Draft manuscript of a report to the Office of Policy Analysis and Resource Management, U.S. Environmental Protection Agency, Washington, 1983

    Google Scholar 

  • Sellar C, Chavas J-P, Stoll JR. Validation of empirical measures of welfare change: a comparison of nonmarket techniques. Land Economics 61: 156–175, 1985

    Article  Google Scholar 

  • Smith VL. The principle of unanimity and voluntary consent in social choice. Journal of Political Economy 85: 1125–1139, 1977

    Article  Google Scholar 

  • Smith VL (Ed.). Research in experimental economics, Vol 1, JAI Press, Connecticut, 1979

    Google Scholar 

  • Smith VK, Desvousges WH. Measuring water quality benefits, Kluwer-Nijhoff Publishing, Boston, 1986

    Book  Google Scholar 

  • Smith VK, Desvousges WH. An empirical analysis of the economic value of risk changes. Journal of Political Economy 95: 89–115, 1987

    Article  Google Scholar 

  • Sorg C, Brookshire DS. Valuing increments and decrements of wildlife resources: further evidence, Report to the Rocky Mountain Forest and Range Experiment Station, U.S. Forest Service, Fort Collins Colorado, 1984

    Google Scholar 

  • Sugden R, Williams A. The principles of practical cost-benefit analysis, Oxford University Press, Oxford, 1978

    Google Scholar 

  • Thayer MA. Contingent valuation techniques for assessing environmental impacts: further evidence. Journal of Environmental Economics and Management 8: 27–44, 1981

    Article  Google Scholar 

  • Thompson MS. Willingness to pay and accept risks to cure chronic disease. American Journal of Public Health 76: 392–396, 1986

    Article  PubMed  CAS  Google Scholar 

  • Weinstein MC, Stason WB. Hypertension: a policy perspective, Harvard University Press, Cambridge, 1976

    Google Scholar 

  • Weisbrod B. Economics of public health, University of Pennsylvania Press, Philadelphia, 1961

    Google Scholar 

  • Williams A. Economics of coronary artery bypass grafting. British Medical Journal 291: 326–329, 1985

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Johannesson, M., Johansson, PO. & Jönsson, B. Economic Evaluation of Drug Therapy. Pharmacoeconomics 1, 325–337 (1992). https://doi.org/10.2165/00019053-199201050-00004

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00019053-199201050-00004

Keywords

Navigation