Abstract
Childhood obesity has reached epidemic proportions worldwide and is associated with increased cardiovascular mortality and morbidity in adult life. The increase in fat mass in children and adolescents has occurred concomitantly with a decline in reported time for exercise. Evidence suggests that non-physically active children are more likely to become non-physically active adults and that encouraging the development of physical activity habits in children helps establish patterns that continue into adulthood. Dietary treatment of obesity is relatively ineffective in adults and it has been suggested that prevention of obesity in childhood and adolescence should emphasise increased physical activity rather than diet because of fears relating to the adverse effects of inappropriate eating patterns. Despite this, there are very few randomised controlled studies investigating the efficacy of exercise training in obese children or adolescents and many of the extant studies have been poorly controlled and have not specifically stratified the independent effect of exercise versus dietary modification.
This review focuses on the well designed controlled trials that have evaluated the effect of exercise training in obese children and adolescents on body composition, haemodynamic and metabolic variables, cardiovascular fitness, muscular strength and vascular function. These studies indicate that, although exercise training does not consistently decrease bodyweight or body mass index, it is associated with beneficial changes in fat and lean body mass, emphasising the importance of comprehensive assessment of body composition in future exercise-training studies. Exercise training improves cardiovascular fitness and muscular strength; however, it seems to have little effect on blood lipid profile or blood pressure in obese young people. Importantly, recent studies have demonstrated that exercise training improves vascular endothelial function, an important surrogate measure that may predict future atherosclerotic risk in obese children and adolescents. Given that improvement in vascular function in these training studies occurred in the absence of changes in lipid fractions, haemodynamic variables or glucose metabolism, exercise appears to have a direct beneficial effect on the vasculature, in addition to its putative benefits through risk-factor modification.
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References
Eckel RH, Krauss RM. American Heart Association call to action: obesity as a major risk factor for coronary heart disease. Circulation 1998; 97: 2099–100
Freedman DS, Srinivasan SR, Valdez RA, et al. Secular increases in relative weight and adiposity among children over two decades: the Bogalusa Heart Study. Pediatrics 1997; 99: 420–6
Troiano RP, Flegal KM. Overweight children and adolescents: description, epidemiology and demographics. Pediatrics 1998; 101: 497–504
Reilly JJ, Dorosty AR, Emmett PM. Prevalence of overweight and obesity in British children: cohort study. BMJ 1999; 319: 1039–41
Deckelbaum RJ, Williams CL. Childhood obesity: the health issue. Obes Rev 2001; 9 Suppl. 4: 239S-43S
Schonfeld-Warden N, Warden CH. Pediatric obesity: an overview of etiology and treatment. Ped Endocrin 1997; 44: 339–60
Must A, Jacques PF, Dallal GE, et al. Long-term morbidity and mortality of overweight adolescents: a follow up of the Harvard Growth Study of 1922–1935. N Engl J Med 1992; 327: 1350–5
Mossberg HO. 40-year follow-up of overweight children. Lancet 1989; II: 491–3
Rosenbaum M, Leibel RL, Hirsch J. Obesity. N Engl J Med 1997; 337: 396–407
Centers for Disease Control and Prevention. Promoting better health for young people through physical activity and sports. A report to the President from the Secretary of Health and Human Services and the Secretary of Education. Silverspring (MD): US Department of Health and Human Services and Department of Education, 2000
Moon L, Meyer P, Grau J. Australia’s young people: their health and wellbeing 1999. Canberra: Australian Institute of Health and Welfare, 1999 Cat. no.: PHE 19
Powell KE, Dysinger W. Childhood participation in organised school sports and physical education as precursors of adult physical activity. Am J Prev Med 1987; 3: 276–81
Riddoch C. Relationships between physical activity and physical health in young people. In: Biddle S, Sallis J, Cavill N, editors. Young and active? Young people and health-enhancing physical activity. evidence and implications. London: Health Education Authority, 1998
Nutbeam D, Wise M, Bauman A, et al. Goals and targets for Australia’s health in the year 2000 and beyond. Canberra: Commonwealth Department of Health, Housing and Community Services, 1993
Hills AP, Parker AW. Obesity management via diet and exercise intervention. Child Care Health Dev 1988; 14: 409–16
Reybrouck T, Vinckx J, Van Den Berghe G, et al. Exercise therapy and hypocaloric diet in the treatment of obese children and adolescents. Acta Paediatr Scand 1990; 79: 84–9
Epstein LH, Wing RR, Koeske R, et al. Effects of diet plus exercise on weight change in parents and children. J Consult Clin Psychol 1984; 52: 429–37
Epstein LH, Valoski AM, Vara LS, et al. Effects of decreasing sedentary behavior and increasing activity on weight change in obese children. Health Psychol 1995; 14: 109–15
Epstein LH, Wing RR, Penner BC, et al. Effect of diet and controlled exercise on weight loss in obese children. J Pediatrics 1985; 107: 358–61
Epstein LH, Wing RR, Koeske R, et al. A comparison of lifestyle exercise, aerobic exercise and calisthenics on weight loss in obese children. Behav Ther 1985; 16: 345–56
Rocchini AP, Katch V, Anderson J, et al. Blood pressure in obese adolescents: effect of weight loss. Pediatrics 1998; 82: 16–23
Becque MD, Katch VL, Rocchini AP, et al. Coronary risk incidence of obese adolescents: reduction by exercise plus diet intervention. Pediatrics 1988; 81: 605–12
Watts K, Beye P, Siafarikas A, et al. Exercise training normalises vascular dysfunction and improves central adiposity in obese adolescents. J Am Coll Cardiol 2004; 43: 1823–7
Watts K, Beye P, Siafarikas A, et al. Effects of exercise training on vascular function in obese children. J Pediatrics 2004; 144: 620–5
Owens S, Gutin B, Allison J, et al. Effect of physical training on total and visceral fat in obese children. Med Sci Sports Exerc 1999; 31: 143–8
Humphries MC, Gutin B, Barbeau P, et al. Relations of adiposity and effects of training on the left ventricle in obese youths. Med Sci Sports Exerc 2002; 34: 1428–35
Woo KS, Chook P, Yu CW, et al. Effects of diet and exercise on obesity-related vascular dysfunction in children. Circulation 2004; 109: 1981–6
Ferguson M, Gutin B, Owens S, et al. Effects of physical training and its cessation on the hemostatic system of obese children. Am J Clin Nutr 1999; 69: 1130–4
Gutin B, Barbeau P, Owens S, et al. Effects of exercise intensity on cardiovascular fitness, total body composition, and visceral adiposity of obese adolescents. Am J Clin Nutr 2002; 75: 818–26
Gutin B, Cucuzzo N, Islam S, et al. Physical training improves body composition of black obese 7- to 11-year-old girls. Obes Res 1995; 3: 305–12
Schwingshandl J, Sudi K, Eibl B, et al. Effect of an individualised training programme during weight reduction on body composition: a randomised trial. Arch Dis Child 1999; 81: 426–8
Ferguson MA, Gutin B, Le N, et al. Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children. Int J Obes 1999; 22: 889–95
Gutin B, Owens S, Slavens G, et al. Effect of physical training on heart-period variability in obese children. J Pediatr 1997; 130: 938–43
Gutin B, Ramsey L, Barbeau P, et al. Plasma leptin concentrations in obese children: changes during 4-mo periods with and without physical training. Am J Clin Nutr 1999; 69: 388–94
Hayashi T, Fujino M, Shindo M, et al. Echocardiographic and electrocardiographic measures in obese children after an exercise program. Int J Obes 1987; 11: 465–72
Treuth MS, Hunter GR, Pichon C, et al. Fitness and energy expenditure after strength training in obese prepubertal girls. Med Sci Sports Exerc 1998; 30: 1130–6
Treuth MS, Hunter GR, Figueroa-Colon R, et al. Effects of strength training on intra-abdominal adipose tissue in obese prepubertal girls. Med Sci Sports Exerc 1998; 30: 1738–43
Pollock ML, Gaesser GA, Butcher JD, et al. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc 1998; 30: 975–91
McArdle WD, Katch FI, Katch VL. Exercise physiology: energy, nutrition, and human performance. 4th ed. Baltimore (MD): Williams & Wilkins, 1996
Epstein LH, Wing RR, Koeske R, et al. A comparison of lifestyle change and programmed aerobic exercise on weight and fitness changes in obese children. Behav Ther 1982; 13: 651–65
Epstein LH, Valoski A, Wing RR, et al. Ten year outcomes of behavioural family-based treatment for childhood obesity. Health Psychol 1994; 13: 373–83
Bloomfield J, Ackland TR, Elliott BC. Applied anatomy and biomechanics in sport. Melbourne: Blackwell Scientific Publications, 1994
Ivy JL. Role of exercise training in the prevention and treatment of insulin resistance and non-insulin-dependent diabetes mellitus. Sports Med 1997; 24: 321–36
Dulloo AG, Jacquet J. Adaptive reduction in basal metabolic rate in response to food deprivation in humans: a role for negative feedback signals from fat stores. Am J Clin Nutr 1998; 68: 599–606
Blimkie C. Resistance training during preadolescence: issues and controversies. Sports Med 1993; 15: 389–407
Lillegard W, Terrio J. Appropriate strength training. Med Clin North Am 1994; 78: 457–77
American Academy of Pediatrics. Strength training, weight and power lifting, and body building by children and adolescents. Pediatrics 1990; 86: 801–3
Buemann B, Tremblay A. Effects of exercise training on abdominal obesity and related metabolic complications. Sports Med 1996; 3: 191–212
Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996; 334: 292–5
Lahlou N, Landais P, De Boissieu D, et al. Circulating leptin in normal children and during the dynamic phase of juvenile obesity: relation to body fatness, energy metabolism, caloric intake, and sexual dimorphism. Diabetes 1997; 46: 989–93
Celermajer DS, Sorensen KE, Gooch VM, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111–5
Joannides R, Haefeli WE, Linder L, et al. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 1995; 91: 1314–9
Doshi SN, Naka KK, Payne N, et al. Flow-mediated dilatation following wrist and upper arm occlusion in humans: the contribution of nitric oxide. Clin Sci 2001; 101: 629–35
Vita JA, Keaney JF. Endothelial function: a barometer for cardiovascular risk? Circulation 2002; 106: 640–2
Maiorana A, O’Driscoll G, Cheetham C, et al. The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes. J Am Coll Cardiol 2001; 38: 860–6
Green DJ, Maiorana A, O’Driscoll G, et al. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol (Lond) 2004; 561: 1–25
Tounian P, Aggoun Y, Dubern B, et al. Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet 2001; 358: 1400–4
Pohl U, Holtz J, Busse R, et al. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 1986; 8: 37–44
Hambrecht R, Adams V, Erbs S, et al. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 2003; 107: 3152–8
Modena MG, Bonetti L, Coppi F, et al. Prognostic role of reversible endothelial dysfunction in hypertensive postmenopausal women. J Am Coll Cardiol 2002; 40: 505–10
Maiorana A, O’Driscoll GJ, Taylor RR, et al. Exercise and the nitric oxide vasodilator system. Sports Med 2003; 33: 1013–35
Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000; 101 (16): 1899–906
Al Suwaidi J, Hamasaki S, Higano ST, et al. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 2000; 101: 948–54
Halcox JP, Schenke WH, Zalos G, et al. Prognostic value of coronary vascular endothelial function. Circulation 2002; 106: 653–8
Heitzer T, Schlinzig T, Krohn K, et al. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673–8
Perticone F, Ceravolo R, Puji A, et al. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 2001; 104: 191–6
Gocke N, Keaney JF, Hunter LM, et al. Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 2002; 105: 1567–72
Neunteufl T, Heher S, Katzenschlager R, et al. Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain. Am J Cardiol 2000; 86: 207–10
O’Driscoll JG, Green DJ, Maiorana A, et al. Improvement in endothelial function by ACE inhibition in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 1999; 33: 1506–11
O’Driscoll G, Green D, Taylor R. Simvastatin, an HMG-Coenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997; 95: 1126–31
Hambrecht R, Wolf A, Geilen S, et al. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 2000; 342: 454–60
Belardinelli R, Georgiou D, Cianci G, et al. Randomised, controlled trial of long-term moderate exercise training in chronic heart failure: effects on functional capacity, quality of life, and clinical outcome. Circulation 1999; 99: 1173–82
Farrell SW, Braun L, Barlow CE, et al. The relation of body mass index, cardiorespiratory fitness, and all-cause mortality in women. Obes Res 2002; 10: 417–23
Barlow CE, Kohl HW, Gibbons LW, et al. Physical fitness, mortality and obesity. Int J Obes 1995; 19 Suppl. 4: S41–4
Blair SN, Cheng YJ, Holder JS. Is physical activity or physical fitness more important in defining health benefits. Med Sci Sports Exerc 2001; 33 Suppl. 6: S379–99
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Supported by the National Heart Foundation of Australia. The authors have no conflicts of interest that are directly relevant to the content of this review.
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Watts, K., Jones, T.W., Davis, E.A. et al. Exercise Training in Obese Children and Adolescents. Sports Med 35, 375–392 (2005). https://doi.org/10.2165/00007256-200535050-00002
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DOI: https://doi.org/10.2165/00007256-200535050-00002
Keywords
- Exercise Training
- Resistance Training
- Obese Child
- Resistance Exercise
- Aerobic Exercise