Abstract
Anterior cruciate ligament (ACL) injuries are recognised with greater frequency in children and adolescents. Non-operative treatment of ACL injuries in children may lead to knee instability and secondary injuries, especially in those who return to sports. ACL reconstruction is controversial in skeletally immature patients because of potential damage to the proximal tibial and distal femoral physes, which may lead to premature arrest and/or leg length discrepancies. This paper reviews studies of ACL injuries in children and adolescents, and examines basic science and clinical studies concerning physeal arrest secondary to ACL reconstruction tunnels. Some animal studies support the conclusion that ACL reconstructions in children have the potential to cause growth disturbances, and there are reports of growth plate complications due to ACL reconstruction in skeletally immature patients. There is evidence that ACL reconstruction can be performed in select skeletally immature patients, but the risk of growth plate complications must be considered.
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References
Auringer ST, Anthony EY. Common pediatric sports injuries. Semin Musculoskelet Radiol 1999; 3: 247–56
Iobst CA, Stanitski CL. Acute knee injuries. Clin Sports Med 2000; 19: 621–35
Micheli LJ. Pediatric and adolescent sports injuries: recent trends. Exerc Sport Sci Rev 1986; 14: 359–74
Tohyama H, Kutsumi K, Yasuda K. Avulsion fracture at the femoral attachment of the anterior cruciate ligament after intercondylar eminence fracture of the tibia. Am J Sports Med 2002; 30: 279–82
Micheli LJ, Metzl JD, Di Canzio J, et al. Anterior cruciate ligament reconstructive surgery in adolescent soccer and basketball players. Clin J Sport Med 1999; 9: 138–41
Shea K, Wang J, Pfeiffer R, et al. Age related risk factors for ACL injury in pediatric and adolescent soccer players-differences between male and females. American Academy of Orthopaedic Surgeons Annual Meeting; 2001 Feb; San Francisco. Orlando (FL): American Academy of Orthopaedic Surgeons, 2001
Arendt E, Dick R. Knee injury patterns among men and women in collegiate basketball and soccer: NCAA data and review of literature. Am J Sports Med 1995; 23: 694–701
Powell JW, Barber-Foss KD. Sex-related injury patterns among selected high school sports. Am J Sports Med 2000; 28: 385–91
Hewett TE. Neuromuscular and hormonal factors associated with knee injuries in female athletes: strategies for intervention. Sports Med 2000; 29: 313–27
Harmon KG, Dick R. The relationship of skill level to anterior cruciate ligament injury. Clin J Sport Med 1998; 8: 260–5
Rozzi SL, Lephart SM, Gear WS, et al. Knee joint laxity and neuromuscular characteristics of male and female soccer and basketball players. Am J Sports Med 1999; 27: 312–9
Barrett GR, Rose JM, Ried EM. Relationship of anterior cruciate ligament injury to notch width index (a roentgenographic study). J Miss State Med Assoc 1992; 33: 279–83
Good L, Odensten M, Gillquist J. Intercondylar notch measurements with special reference to anterior cruciate ligament surgery. Clin Orthop 1991; 263: 185–9
Teitz CC, Lind BK, Sacks BM. Symmetry of the femoral notch width index. Am J Sports Med 1997; 25: 687–90
Myklebust G, Maehlum S, Holm I, et al. A prospective cohort study of anterior cruciate ligament injuries in elite Norwegian team handball. Scand J Med Sci Sports 1998; 8: 149–53
Wolman RL. Association between the menstrual cycle and anterior cruciate ligament in female athletes. Am J Sports Med 1999; 27: 270–1
Aichroth PM, Patel DV, Zorrilla P. The natural history and treatment of rupture of the anterior cruciate ligament in children and adolescents: a prospective review. J Bone Joint Surg Br 2002; 84: 38–41
Angel KR, Hall DJ. Anterior cruciate ligament injury in children and adolescents. Arthroscopy 1989; 5: 197–200
Graf BK, Lange RH, Fujisaki CK, et al. Anterior cruciate ligament tears in skeletally immature patients: meniscal pathology at presentation and after attempted conservative treatment. Arthroscopy 1992; 8: 229–33
Janarv PM, Nystrom A, Werner S, et al. Anterior cruciate ligament injuries in skeletally immature patients. J Pediatr Orthop 1996; 16: 673–7
McCarroll JR, Rettig AC, Shelbourne KD. Anterior cruciate ligament injuries in the young athlete with open physes. Am J Sports Med 1988; 16: 44–7
McCarroll JR, Shelbourne KD, Porter DA, et al. Patellar tendon graft reconstruction for midsubstance anterior cruciate ligament rupture in junior high school athletes: an algorithm for management. Am J Sports Med 1994; 22: 478–84
Mizuta H, Kubota K, Shiraishi M, et al. The conservative treatment of complete tears of the anterior cruciate ligament in skeletally immature patients. J Bone Joint Surg Br 1995; 77: 890–4
Pressman AE, Letts RM, Jarvis JG. Anterior cruciate ligament tears in children: an analysis of operative versus nonoperative treatment. J Pediatr Orthop 1997; 17: 505–11
Woods GW, O’Connor DP. Delayed anterior cruciate ligament reconstruction in skeletally immature adolescents. Am J Sports Med. In press
Tegner Y, Lysholm J. Derotation brace and knee function in patients with anterior cruciate ligament tears. Arthroscopy 1985; 1: 264–7
Kocher MS, Micheli LJ, Zurakowski D, et al. Partial tears of the anterior cruciate ligament in children and adolescents. Am J Sports Med 2002; 30: 697–703
Campbell CJ, Grisolia A, Zanconato G. The effects produced in the cartilagenous epiphyseal plate of immature dogs by experimental surgical trauma. J Bone Joint Surg 1959; 41A: 1221–42
Ford LT, Key J. A study of experimental trauma to the distal femoral epiphysis in rabbits. J Bone Joint Surg 1956; 38:84–92
Guzzanti V, Falciglia F, Gigante A, et al. The effect of intra-articular ACL reconstruction on the growth plates of rabbits. J Bone Joint Surg Br 1994; 76: 960–3
Mäkelä EA, Vainionpaa S, Vihtonen K, et al. The effect of trauma to the lower femoral epiphyseal plate: an experimental study in rabbits. J Bone Joint Surg Br 1988; 70: 187–91
Nordentoft EL. Experimental epiphyseal injuries: grading of traumas and attempts at treating traumatic epiphyseal arrest in animals. Acta Orthop Scand 1969; 40: 176–92
Janarv PM, Wikstrom B, Hirsch G. The influence of transphyseal drilling and tendon grafting on bone growth: an experimental study in the rabbit. J Pediatr Orthop 1998; 18: 149–54
Ono T, Wada Y, Takahashi K, et al. Tibial deformities and failures of anterior cruciate ligament reconstruction in immature rabbits. J Orthop Sci 1998; 3: 150–5
Stadelmaier DM, Arnoczky SP, Dodds J, et al. The effect of drilling and soft tissue grafting across open growth plates: a histologic study. Am J Sports Med 1995; 23: 431–5
Haas S. Restriction of bone growth by pins through the epiphyseal cartilaginous growth plate. J Bone Joint Surg 1950; 22A: 338–43
Kocher MS, Saxon HS, Hovis WD, et al. Management and complications of anterior cruciate ligament injuries in skeletally immature patients: survey of the Herodicus Society and The ACL Study Group. J Pediatr Orthop 2002; 22: 452–7
Edwards TB, Greene CC, Baratta RV, et al. The effect of placing a tensioned graft across open growth plates: a gross and histologic analysis. J Bone Joint Surg Am 2001; 83: 725–34
Phemister D. Operative arrestment of longitudinal growth of bones in the treatment of deformities. J Bone Joint Surg 1933; 15: 1–5
Houle JB, Letts M, Yang J. Effects of a tensioned tendon graft in a bone tunnel across the rabbit physis. Clin Orthop 2001; 391: 275–81
Shea K, Apel P, Showalter LD, et al. ACL reconstruction in children: minimizing the injury to the proximal tibia physis with variation in tibial drill hole placement. American Academy of Orthopaedic Surgeons Annual Meeting; 2001 Feb; San Francisco. Orlando (FL): American Academy of Orthopaedic Surgeons, 2001
Behr CT, Potter HG, Paletta Jr GA. The relationship of the femoral origin of the anterior cruciate ligament and the distal femoral physeal plate in the skeletally immature knee: an anatomic study. Am J Sports Med 2001; 29: 781–7
Gelbke H. The influence of pressure and tension on growing bone in experiments with animals. J Bone Joint Surg 1951; 33: 947–53
Porter RW. The effect of tension across a growing epiphysis. J Bone Joint Surg Br 1978; 60B: 252–5
Yasuda K, Tsujino J, Tanabe Y, et al. Effects of initial graft tension on clinical outcome after anterior cruciate ligament reconstruction: autogenous doubled hamstring tendons connected in series with polyester tapes. Am J Sports Med 1997; 25: 99–106
Yoshiya S, Kurosaka M, Ouchi K, et al. Graft tension and knee stability after anterior cruciate ligament reconstruction. Clin Orthop 2002; 394: 154–60
Shea KG, Apel PJ, Pfeiffer RP, et al. The tibial attachment of the anterior cruciate ligament in children and adolescents: analysis of magnetic resonance imaging. Knee Surg Sports Traumatol Arthrosc 2002; 10: 102–8
Matava MJ, Siegel MG. Arthroscopic reconstruction of the ACL with semitendinosus-gracilis autograft in skeletally immature adolescent patients. Am J Knee Surg 1997; 10: 60–9
Lo IK, Kirkley A, Fowler PJ, et al. The outcome of operatively treated anterior cruciate ligament disruptions in the skeletally immature child. Arthroscopy 1997; 13: 627–34
Koman JD, Sanders JO. Valgus deformity after reconstruction of the anterior cruciate ligament in a skeletally immature patient: a case report. J Bone Joint Surg Am 1999; 81: 711–5
Lipscomb AB, Anderson AF. Tears of the anterior cruciate ligament in adolescents. J Bone Joint Surg Am 1986; 68:19–28
Oni OO. Physeal arrest [letter]. J Bone Joint Surg Am 2000; 82A: 1204
Sanders JO. Anterior cruciate ligament reconstruction in the skeletally. Arthroscopy 2000; 16(4): 392–3
Kocher MS, Steadman RJ, Briggs K, et al. Determinants of patient satisfaction with outcome after anterior cruciate ligament reconstruction. J Bone Joint Surg Am 2002; 84A: 1560–72
DeLee JC, Curtis R. Anterior cruciate ligament insufficiency in children. Clin Orthop 1983; 172: 112–8
Engebretsen L, Benum P, Sundalsvoll S. Primary suture of the anterior cruciate ligament: a 6-year follow-up of 74 cases. Acta Orthop Scand 1989; 60: 561–4
Engebretsen L, Svenningsen S, Benum P. Poor results of anterior cruciate ligament repair in adolescence. Acta Orthop Scand 1988; 59: 684–6
Marshall JL, Warren RF, Wickiewicz TL, et al. The anterior cruciate ligament: a technique of repair and reconstruction. Clin Orthop 1979; 143: 97–106
Brief LP. Anterior cruciate ligament reconstruction without drill holes. Arthroscopy 1991; 7: 350–7
Micheli LJ, Rask B, Gerberg L. Anterior cruciate ligament reconstruction in patients who are prepubescent. Clin Orthop 1999; 364: 40–7
Robert H, Bonnard C. The possibilities of using the patellar tendon in the treatment of anterior cruciate ligament tears in children. Arthroscopy 1999; 15: 73–6
Andrews M, Noyes FR, Barber-Westin SD. Anterior cruciate ligament allograft reconstruction in the skeletally immature athlete. Am J Sports Med 1994; 22: 48–54
Bisson LJ, Wickiewicz T, Levinson M, et al. ACL reconstruction in children with open physes. Orthopedics 1998; 21: 659–63
Aronowitz ER, Ganley TJ, Goode JR, et al. Anterior cruciate ligament reconstruction in adolescents with open physes. Am J Sports Med 2000; 28: 168–75
Parker AW, Drez Jr D, Cooper JL. Anterior cruciate ligament injuries in patients with open physes. Am J Sports Med 1994; 22(1): 44–7
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No funding was used to assist in the preparation of this manuscript and there are no conflicts of interest with respect to any of the authors and the information presented in this paper.
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Shea, K.G., Apel, P.J. & Pfeiffer, R.P. Anterior Cruciate Ligament Injury in Paediatric and Adolescent Patients. Sports Med 33, 455–471 (2003). https://doi.org/10.2165/00007256-200333060-00006
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DOI: https://doi.org/10.2165/00007256-200333060-00006