Skip to main content
SpringerLink
Log in

Aspirin and Exercise as a Prophylaxis for Heart Disease

Is it Safe?

  • Leading Article
  • Published:
Sports Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Aspirin Myocardial Infarction Study Research Group. A randomized controlled trial of aspirin in persons recovered from myocardial infarction. Journal of the American Medical Association 243: 661–669, 1980

    Article  Google Scholar 

  • Carlson LA, Ostman J. Effect of salicylates on plasma free fatty acid in normal and diabetic subjects. Metabolism 10: 781–787, 1960

    Google Scholar 

  • Chakrabarti R, Hocking ED, Fearnley GR, Mann RD, Attwell TN, et al. Fibrinolytic activity and coronary artery disease. Lancet 1: 987–990, 1968

    Article  PubMed  CAS  Google Scholar 

  • Cryglewski RJ. Structure activity relationship of some prosta-glandin synthetase inhibitors. In Robinson & Vans (Eds) Prostaglandin synthetase inhibitors, pp. 33–52, Raven Press, New York, 1974

    Google Scholar 

  • De Meersman RE. Effects of acetylsalicylic acid on respiration during exercise in women. Current Therapeutic Research 41: 194–198, 1987

    Google Scholar 

  • De Meersman, RE. The effects of acetylsalicylic acid upon carbohydrate metabolism during exercise. International Journal of Clinical Pharmacology Therapy and Toxicology 26: 461–464, 1988

    Google Scholar 

  • De Meersman RE. Thermal, ventilatory and glucoregulatory responses during exercise following short term acetylsalicylic acid ingestion. International Journal of Clinical Pharmacology Research VIII(6): 477–483, 1988

    Google Scholar 

  • Downey JA, Darling RC. Effects of salicylates on elevation of body temperature during exercise. Journal of Applied Physiology 17: 323, 1962

    PubMed  CAS  Google Scholar 

  • Dunn NJ, Zambraski EJ. Renal effects of drugs that inhibit prostaglandin synthesis. Kidney International 18: 609–622, 1980

    Article  PubMed  CAS  Google Scholar 

  • Fclig P, Wahren J. Fuel homeostasis in exercise. New England Journal of Medicine 293: 1078–1084, 1975

    Article  Google Scholar 

  • Folts JD, Crowcll Jr EB, Rowe GG. Platelet aggregation in partially obstructed vessels and its elimination with aspirin. Circulation 54: 365–370, 1976

    Article  PubMed  CAS  Google Scholar 

  • Fred HL. Reflections on a 10 mile run: effects of aspirin therapy. Medicine and Science in Sports and Exercise 12: 212–215, 1980

    Article  PubMed  CAS  Google Scholar 

  • Harker LA, Ritchie JL. The role of platelets in acute vascular events. Circulation 62(Suppl. 5): V–13–8, 1980

    Google Scholar 

  • Hennekens CH, Eberlein KA (for the Physicians’ Health Study Research Group) A randomized trial of aspirin and B carotene among US physicians. Preventative Medicine 14: 165–168, 1985

    Article  CAS  Google Scholar 

  • Hermanssen L, Hultman E, Saltin B. Muscle glycogen during prolonged severe exercise. Acta Physiologica Scandinavica 71: 129–139, 1967

    Article  Google Scholar 

  • Hetzel BS. Metabolic effects of salicylates in man. Metabolism 8: 205, 1959

    PubMed  CAS  Google Scholar 

  • Heyden S, Fodor GJ. Does regular exercise prolong life expectancy? Sports Medicine 6: 63–71, 1988

    Article  PubMed  CAS  Google Scholar 

  • Johnson SC, Ruhling, RO. Aspirin in exercise induced hyper-thermia; evidence for and against its role. Sports Medicine 2: 1–7, 1985

    Article  PubMed  CAS  Google Scholar 

  • Joslin E, Root H, White P. The treatment of diabetes mellitus. 9th ed., Kimpton, London, 1952

    Google Scholar 

  • Kernoff PBA, McNicol GP. Normal and abnormal fibrinolysis. British Medical Bulletin 33: 239–244, 1977

    PubMed  CAS  Google Scholar 

  • Micossi P, Ponteirelli AE, Baron SH. Aspirin stimulates insulin and glucagon secretion and increased glucose tolerance in normal and diabetic subjects. Diabetes 27(12): 1196–1204, 1978

    Article  PubMed  CAS  Google Scholar 

  • Morris JN, Crawford MD. Coronary heart disease and physical activity at work. British Medical Journal 2: 1485–1496, 1958

    Article  PubMed  CAS  Google Scholar 

  • Morris JN, Everitt MG, Pollard R, Chave SPW, Semmence AM. Vigorous exercise in leisure time: protection against coronary heart disease. Lancet 2: 1207–1210, 1980

    Article  PubMed  CAS  Google Scholar 

  • Nadel ER. Temperature regulation during exercise. In Houdas & Guieu (Eds) New trends in thermal physiology, pp. 143–153, Paris, Masson, 1978

    Google Scholar 

  • Nadel ER. Control of sweating rate while exercising in the heat. Medicine and Science in Sports 11(1): 31–35, 1979

    PubMed  CAS  Google Scholar 

  • Paffenberger Jr RS, Hyde RT, Wing AL, Hsieh CC. Physical activity, all-cause mortality and longevity of college alumni. New England Journal of Medicine 314: 605–613, 1986

    Article  Google Scholar 

  • Rowell LB. Human cardiovascular adjustments to exercise and thermal stress. Physiological Reviews 54: 75–159, 1974

    PubMed  CAS  Google Scholar 

  • Saynavalammi P, Pyykonen ML, Veitalo P, Vapaatalo A. Prostaglandins in the regulation of circulation and blood pressure. Medical Biology 57: 35–51, 1979

    Google Scholar 

  • Senay Jr LC. Plasma volume and constituents of heat exposed men before and after acclimatization. Journal of Applied Physiology 38: 570–575, 1975

    PubMed  Google Scholar 

  • Senay JR LC. Early response of plasma contents on exposure of working men to heat. Journal of Applied Physiology 44: 166–170, 1978

    PubMed  Google Scholar 

  • Smith MJH. Salicylates and metabolism. Journal of Pharmacy and Pharmacology 11: 705, 1959

    Article  PubMed  CAS  Google Scholar 

  • Sproull DH. The glycogenolytic action of sodium salicylate. British Journal of Pharmacology 9: 121, 1954

    CAS  Google Scholar 

  • Physicians’ Health Study Research Group. Preliminary report. New England Journal of Medicine 318: 262–265, 1988

    Article  Google Scholar 

  • Wasserman K, Whipp BJ. Exercise physiology in health and disease. American Reviews of Respiratory Diseases 112: 219–249, 1975

    CAS  Google Scholar 

  • Weiss H, Aledort L, Kochwa S. The effect of salicyaltes on the hemostatic properties of platelets in man. Journal of Clinical Investigations 47: 2169, 1968

    Article  CAS  Google Scholar 

  • Whitney AL, Ryan AJ. The effects of acetylsalicylic acid on free fatty acids in blood and possible relationship to aerobic performance. Sports Medicine and Physical Fitness 11(2): 93, 1971

    CAS  Google Scholar 

  • Williams SR, Logue EE, Lewis JL, Barton T, Stead NW, et al. Physical conditioning augments the fibrinolytic response to venous occlusion in healthy adults. New England Journal of Medicine 302: 987–991, 1980

    Article  PubMed  CAS  Google Scholar 

  • Zambraski EJ, Rofrano TA, Ciccone CD. Effects of aspirin treatment on kidney function in exercising man. Medicine and Science in Sports and Exercise 14: 419–423, 1980

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Applied Physiology Laboratory, Teachers College - Columbia University, Box 199, 323D Thompson Hall, New York, NY, 10027, USA

    Ronald E. De Meersman

Authors
  1. Ronald E. De Meersman
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

De Meersman, R.E. Aspirin and Exercise as a Prophylaxis for Heart Disease. Sports Med 9, 71–75 (1990). https://doi.org/10.2165/00007256-199009020-00001

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00007256-199009020-00001

Keywords

Search

Navigation