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Recombinant Full-Length Parathyroid Hormone (1–84)

A Viewpoint by James Whitfield

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References

  1. Tregear GW, van Rietschoten J, Greene E, et al. Solid-phase synthesis of the biologically active N-terminal 1–34 peptide of the human parathyroid hormone. Hoppe Seylers Z Physiol Chem 1974; 355 (4): 415–421

    Article  PubMed  CAS  Google Scholar 

  2. Whitfield JF. Osteoporosis-treating parathyroid hormone peptides: What are they? What do they do? How do they do it? Curr Opin Invest Drugs 2006; 7 (4): 349–359

    CAS  Google Scholar 

  3. NPS® Pharmaceuticals. NPS receives approvable letter for PREOS NDA. 2006 Mar 10 [online]. Available from URL: http://www.npsp.com/news/releasetxt.php?ReqId=830043 [Accessed 2006 Nov 15]

  4. Whitfield JF, Morley P, Willick G, et al. Stimulation of the growth of femoral trabecular bone in ovariectomized rats by the novel parathyroid hormone fragment hPTH-(1-31)NH2 (ostabolin). Calcif Tissue Int 1996; 58 (2): 81–87

    Article  PubMed  CAS  Google Scholar 

  5. Whitfield JF, Morley P, Willick G, et al. Comparison of the ability of recombinant human parathyroid hormone, rhPTH-(1–84) and hPTH-(1–31)NH2 to stimulate femoral trabecular bone growh in ovariectomized rats. Calcif Tissue Int 1997; 60 (1): 26–29

    Article  PubMed  CAS  Google Scholar 

  6. Vahle JL, Long GG, Sandusky, G, et al. Bone neoplasms in F344 rats given teriparatide [rhPTH(1–34)] are dependent on duration of treatment and dose. Toxicol Pathol 2004; 32 (4): 426–438

    Article  PubMed  CAS  Google Scholar 

  7. Morley P. Delivery of parathyroid hormone for the treatment of osteoporosis. Expert Opin Drug Deliv 2005; 2 (6): 993–1002

    Article  PubMed  CAS  Google Scholar 

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  1. Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada

    James Whitfield

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  1. James Whitfield
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Whitfield, J. Recombinant Full-Length Parathyroid Hormone (1–84). Drugs 66, 2382 (2006). https://doi.org/10.2165/00003495-200666180-00009

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  • DOI: https://doi.org/10.2165/00003495-200666180-00009

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