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Recent Developments in the Treatment of Otitis Media with Effusion

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Abstract

The management of otitis media with effusion (OME) has received much attention recently as a result of, among other factors, the development of resistant bacteria and the finding of less long-term impact of middle-ear effusion (MEE) on development than previously believed. Guidelines have recently been published for the management of OME promoting more accurate diagnosis, particularly distinguishing acute otitis media from OME, and recommending the ‘judicious’ use of antibacterials. Today, more emphasis is being placed on prevention of disease by reducing risk factors and the development of vaccines. The identification of susceptibility genes may lead to better understanding of the pathogenesis of otitis media, which in turn may lead to the development of more innovative and satisfactory methods for prevention and treatment.

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No sources of funding were used to assist in the preparation of this review. The authors have no conflicts of interest directly related to the contents of this review.

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  1. ENT Research Center, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Ellen M. Mandel & Margaretha L. Casselbrant

  2. Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

    Ellen M. Mandel & Margaretha L. Casselbrant

  3. Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

    Ellen M. Mandel

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Correspondence to Ellen M. Mandel.

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Mandel, E.M., Casselbrant, M.L. Recent Developments in the Treatment of Otitis Media with Effusion. Drugs 66, 1565–1576 (2006). https://doi.org/10.2165/00003495-200666120-00003

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