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Nicotine Replacement Therapy

What Has Been Accomplished — Can We Do Better?

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An Erratum to this article was published on 01 May 1993

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References

  • Abelin T, Buehler A, Muller P, Vesanen K, Imhof PR. Controlled trial of trahsdermal nicotine patch in tobacco withdrawal. Lancet 1: 7–10, 1989

    Article  PubMed  CAS  Google Scholar 

  • Benowitz NL. Pharmacologic aspects of cigarette smoking and nicotine addiction. New England Journal of Medicine 319: 1318–1330, 1988

    Article  PubMed  CAS  Google Scholar 

  • Benowitz NL. Pharmacokinetic considerations in understanding nicotine dependence. In Bock G & Marsh J (Eds) The biology of nicotine dependence, pp. (186–209), Wiley, Chichester, 1990

  • Benowitz NL. Nicotine and coronary heart disease. Trends in Cardiovascular Medicine 1: 315–321, 1991a

    Article  PubMed  CAS  Google Scholar 

  • Benowitz NL. Nicotine replacement therapy during pregnancy. Journal of the American Medical Association 266: 3174–3177, 1991b

    Article  PubMed  CAS  Google Scholar 

  • Benowitz NL. Pharmacodynamics of nicotine. Implications for rational treatment of nicotine addiction. British Journal of Addiction 86: 495–499, 1991c

    Article  PubMed  CAS  Google Scholar 

  • Benowitz, NL. Cigarette smoking and nicotine addiction. Medical Clinics of North America 76: 415–438, 1992

    PubMed  CAS  Google Scholar 

  • Benowitz NL, Jacob P III. Daily intake of nicotine during cigarette smoking. Clinical Pharmacology and Therapeutics 35: 499–504, 1984

    Article  PubMed  CAS  Google Scholar 

  • Benowitz NL, Jacob P III. Intravenous nicotine replacement suppresses nicotine intake from cigarette smoking. Journal of Pharmacology and Experimental Therapeutics 254: 1000–1005, 1990

    PubMed  CAS  Google Scholar 

  • Benowitz NL, Jacob P III, Savanapridi C. Determinants of nicotine intake while chewing nicotine polacrilex gum. Clinical Pharmacology and Therapeutics 41: 467–473, 1987

    Article  PubMed  CAS  Google Scholar 

  • Blondal T. Controlled trial of nicotine polacrilex gum with supportive measures. Archives of Internal Medicine 149: 1818–1821, 1989

    Article  PubMed  CAS  Google Scholar 

  • Cummings SR, Hansen B, Richard RJ, Stein MJ, Coates TJ. Internists and Nicotine Gum. Journal of the American Medical Association 260: 1565–1569, 1988

    Article  PubMed  CAS  Google Scholar 

  • Daughton DM, Heatley SA, Prendergast JJ, Causey D, Knowles M, et al. Effect of transdermal nicotine delivery as an adjunct to low-intervention smoking cessation therapy. Archives of Internal Medicine 151: 749–752, 1991

    Article  PubMed  CAS  Google Scholar 

  • Emont SL, Cummings KM. Weight gain following smoking cessation: A possible role for nicotine replacement in weight management. Addictive Behaviors 12: 151–155, 1987

    Article  PubMed  CAS  Google Scholar 

  • Fagerstrom KO. Reducing the weight gain after stopping smoking. Addictive Behaviors 12: 91–93, 1987

    Article  PubMed  CAS  Google Scholar 

  • Glassman AH, Heizer JE, Covey LS, Cottier LB, Stetner F, et al. Smoking, Smoking cessation, and major depression. Journal of the American Medical Association 264: 1546–1549, 1990

    Article  PubMed  CAS  Google Scholar 

  • Gross J, Stitzer ML. Nicotine replacement: Ten-week effects on tobacco withdrawal symptoms. Psychopharmacology 93: 334–341, 1989

    Article  Google Scholar 

  • Hall SM, Tunstall C, Rugg D, Jones RT, Benowitz N. Nicotine gum and behavioral treatment in smoking cessation. Journal of Consulting and Clinical Psychology 53: 256–258, 1985

    Article  PubMed  CAS  Google Scholar 

  • Hughes JE, Gust SW, Keenan RM, Fenwick J, Healy ML. Nicotine vs placebo gum in general medical practice. Journal of the American Medical Association 261: 1300–1305, 1989

    Article  PubMed  CAS  Google Scholar 

  • Hughes JR, Hatsukami DK, Pickens RW, Krahn D, Malin S, et al. Effect of nicotine on the tobacco withdrawal syndrome. Psychopharmacology 83: 82–87, 1984

    Article  PubMed  CAS  Google Scholar 

  • Hughes JR, Hatsukami DK, Skoog KP. Physical dependence on nicotine in gum. Journal of the American Medical Association 255: 3277–3279, 1986

    Article  PubMed  CAS  Google Scholar 

  • Hurt RD, Lauger GG, Offord KP, Kottke TE, Dale LC. Nicotine-replacement therapy with use of a transdermal nicotine patch. A randomized double-blind placebo-controlled trial. Mayo Clinic Proceedings 65: 1529–1537, 1990

    PubMed  CAS  Google Scholar 

  • Jarvis M, Raw M, Russell MA, Feyerabend C. Randomised controlled trial of nicotine chewing gum. British Medical Journal 285: 537–540, 1982

    Article  PubMed  CAS  Google Scholar 

  • Killen JD, Fortmann SP, Newman B, Varady A. Evaluation of a treatment approach combining nicotine gum with self-guided behavioral treatments for smoking relapse prevention. Journal of Consulting Clinical Psychology 58: 85–92, 1990

    Article  CAS  Google Scholar 

  • Killen JD, Maccoby N, Taylor CB. Nicotine gum and self regulation training in smoking relapse prevention. Behavior Therapy 15: 234–248, 1984

    Article  Google Scholar 

  • Lam W, Sze PC, Sacks HS, Chalmers TC. Meta-analysis of randomised controlled trials of nicotine chewing-gum. Lancet 2: 27–30, 1987

    Article  PubMed  CAS  Google Scholar 

  • Palmer KJ, Buckley MM, Faulds D. Transdermal nicotine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy as an aid to smoking cessation. Drugs 44: 498–529, 1992

    Article  PubMed  CAS  Google Scholar 

  • Pinney JM. Factors affecting availability of treatment. In Henningfield JE & Stitzer ML (Eds) New developments in nicotine-delivery systems, pp. 79–87, Cortland Communications, Ossing, New York, 1990

    Google Scholar 

  • Rose JE, Levin ED, Behm FM, Adivi C, Schur C. Transdermal nicotine facilitates smoking cessation. Clinical Pharmacology and Therapeutics 47: 323–330, 1990

    Article  PubMed  CAS  Google Scholar 

  • Russell MAH, Jarvis MJ, Feyerabend C, Fernö O. Nasal nicotine solution: a potential aid to giving up smoking? British Medical Journal 286: 683–684, 1983b

    Article  PubMed  CAS  Google Scholar 

  • Russell MA, Merriman R, Stapleton J, Taylor W. Effects of nicotine chewing gum as an adjunct to general practitioner’s advice against smoking. British Medical Journal 287: 1782–1785, 1983

    Article  PubMed  CAS  Google Scholar 

  • Russell MAH, Feyerabend C, Cole PV. Plasma nicotine levels after cigarette smoking and chewing nicotine gum. British Medical Journal 1: 1043–1046, 1976a

    Article  PubMed  CAS  Google Scholar 

  • Russell MAH, Wilson C, Feyerabend C, Cole PV. Effect of nicotine chewing gum on smoking behavior and as an aid to cigarette withdrawal. British Medical Journal 2: 391–393, 1976b

    Article  PubMed  CAS  Google Scholar 

  • Sachs DPL, Säwe U, Leischow SJ. Effectiveness of a 16-hour transdermal nicotine patch in a medical practice setting, without intensive group counselling. Archives of Internal Medicine, in press, 1993

  • Schneider NG. Nicotine therapy in smoking cessation: pharmacokinetic considerations. Clinical Pharmacokinetics 23: 169–172, 1992

    Article  PubMed  CAS  Google Scholar 

  • Schneider NG, Jarvik ME, Forsythe AB, Read LL, Elliott ME, et al. Nicotine gum in smoking cessation: a placebo controlled, double-blind trial. Addictive Behaviors 8: 253–261, 1983

    Article  PubMed  CAS  Google Scholar 

  • Stitzer ML. Nicotine-delivery products: Demonstrated and desirable effects. In Henningfield JE & Stitzer ML (Eds) New developments in nicotine-delivery systems, pp. 35–45, Cortland Communications, Ossing, New York, 1991

    Google Scholar 

  • Sutherland G, Stapleton JA, Russell MAH, Jarvis MJ, Hajek P, et al. Randomised controlled trial of nasal nicotine spray in smoking cessation. Lancet 340: 324–329, 1992

    Article  PubMed  CAS  Google Scholar 

  • Tonnesen P, Fryd V, Hansen M, Helsted J, Gunnerson AB, et al. Effect of nicotine chewing gum in combination with group counselling on the cessation of smoking. New England Journal of Medicine 318: 15–18, 1988

    Article  PubMed  CAS  Google Scholar 

  • Tonnesen P, Nørregaard J, Simonsen K Säwe U. A double-blind trial of a 16-hour transdermal nicotine patch in smoking cessation. New England Journal of Medicine 325: 311–315, 1991

    Article  PubMed  CAS  Google Scholar 

  • Transdermal Nicotine Study Group. Transdermal nicotine for smoking cessation. Journal of the American Medical Association 266: 3133–3138, 1991

    Article  Google Scholar 

  • US Department of Health and Human Services. The health consequences of smoking: nicotine addiction. A Report of the Surgeon General 1988

  • West RJ, Jarvis MJ, Russell MAH, Carruthers ME, Feyerabend C. Effect of nicotine replacement on the cigarette withdrawal syndrome. British Journal of Addiction 79: 215–219, 1984

    PubMed  CAS  Google Scholar 

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An erratum to this article is available at http://dx.doi.org/10.1007/BF03259103.

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Benowitz, N.L. Nicotine Replacement Therapy. Drugs 45, 157–170 (1993). https://doi.org/10.2165/00003495-199345020-00001

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