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Superficial Fungal Infections of the Skin

Diagnosis and Current Treatment Recommendations

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Summary

Superficial fungal infections are common. Most diagnoses of fungal infections of the skin can be made by physical examination, assisted by the use of a Wood’s lamp, skin scrapings for microscopic examination, and fungal cultures.

Dermatophyte infections are common at all ages, in both sexes, and they have a worldwide distribution. These infections include tinea capitis, tinea cruris, tinea pedis, tinea corporis, tinea manuum and tinea barbae. Tinea versicolor, caused by Malassezia furfur, and candidal infections are also common.

Treatment modalities include oral and topical agents. Good personal hygiene is an important adjunct to antifungal therapy. Decisions regarding the appropriateness of therapy in a given patient must take into account the extent and location of the infection, the benefits and risks of each of the treatments, and cost.

Oral therapies include griseofulvin, ketoconazole, and itraconazole. There are a large variety of topical treatments, including nystatin, selenium sulfide, tolnaftate, haloprogin, miconazole, clotrimazole, and sodium thiosulfate. Important to successful treatment is compliance with what is sometimes a long course of treatment, and good personal hygiene.

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References

  • Allen HB, Honig PJ, Leyden JJ, McGinley K. Selenium sulfide. Adjunctive therapy for tinea capitis. Pediatrics 69: 81–83, 1982

    PubMed  CAS  Google Scholar 

  • Caputo RV. Fungal infections in children. Dermatology Clinics 4: 137–149, 1986

    Article  CAS  Google Scholar 

  • Caravati C, Hudgins EM, Kelly L. Tinea pedis in children. Cutis 17: 313–314, 1976

    PubMed  Google Scholar 

  • Fitzpatrick RE, Newcomer VD. Dermatophytes and candidiasis. In Feigin et al. (Eds) Textbook of pédiatric infectious diseases, Vol. 1, pp. 818–855, WB Saunders Co, Philadelphia, 1987

    Google Scholar 

  • Frieden IJ. Diagnosis and management of tineas capitis. Pediatric Annals 16: 39–48, 1987

    PubMed  CAS  Google Scholar 

  • Friedman AD. Superficial bacterial and fungal infections of the skin. In Aronoff (Ed.) Advances in pediatric infectious diseases, Vol. 5, pp. 205–219, Year Book Medical Publishers, Chicago, 1990

    Google Scholar 

  • Gan VN, Petruska M, Ginsburg CM. Epidemiology and treatment of tinea capitis. Ketoconazole versus griseofulvin. Pediatric Infectious Disease Journal 1: 46–49, 1987

    Google Scholar 

  • Grant SM, Clissold SP. Itraconazole. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycoses. Drugs 37: 310–344, 1989

    Article  PubMed  CAS  Google Scholar 

  • Hay RJ, Dupont B, Graybill JR. First international symposium on itraconazole. Reviews of Infectious Diseases 9 (Suppl. 1): 100–138, 1987

    Article  Google Scholar 

  • Heel RC, Brogden RN, Carmine PA. Ketoconazole. A review of its therapeutic efficacy in superficial and systemic fungal infections. Drugs 23: 1–36, 1982

    Article  PubMed  CAS  Google Scholar 

  • Lewis JH, Zimmerman HJ, Brenson GD. Hepatic injury associated with ketoconazole therapy. Gastroenterology 86: 503–513, 1984

    PubMed  CAS  Google Scholar 

  • Louse DS, Kan PB, Hirst MA. Ketoconazole blocks adrenal steroid genesis by inhibiting cytochrome P450-dependent enzymes. Journal of Clinical Investigation 71: 1495–1499, 1983

    Article  Google Scholar 

  • Lucky AW. Epidemiology, diagnosis, and management of tinea capitis in the 1980s. Pediatric Dermatology 2: 226–228, 1985

    Google Scholar 

  • Martin-Roig A, Torres-Rodriquez JM, Barlet-Coma A. Double blind study of ketoconazole and griseofulvin in dermatophytes. Pediatric Infectious Disease Journal 7: 37–40, 1988

    Article  Google Scholar 

  • Nelson J. Pocketbook of Pediatric Antimicrobial Therapy. 9th ed, pp. 56–57, Williams and Wilkins, Baltimore, 1991

    Google Scholar 

  • Peter G, Lepow M, McCracken G, Phillips C. Report of the Committee on Infectious Diseases. 22nd edition pp. 470–475, 546–577, American Academy of Pediatrics, Elk Grove Village, 1991

    Google Scholar 

  • Prevost E. The rise and fall of fluorescent tinea capitis. Pediatric Dermatology 1: 127–133, 1983

    Article  PubMed  CAS  Google Scholar 

  • Stein D. Superficial fungal infections. Pediatric Clinics of North America 30: 545–561, 1983

    PubMed  CAS  Google Scholar 

  • Tanz RR, Stagl S, Esterly NB. Comparison of ketoconazole and griseofulvin for treatment of tinea capitis in childhood: a preliminary study. Pediatric Emergency Care 1: 16–18, 1985

    Article  PubMed  CAS  Google Scholar 

  • Tunnessen WW. Practical aspects of bacterial skin infections in children. Pediatric Dermatology 2: 255–265, 1985

    Article  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pediatrics, St Louis University School of Medicine, Cardinal Glennon Children’s Hospital, 1465 S Grand Boulevard, St Louis, Missouri, 63104, USA

    Allan D. Friedman

Authors
  1. George H. Rezabek
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  2. Allan D. Friedman
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Rezabek, G.H., Friedman, A.D. Superficial Fungal Infections of the Skin. Drugs 43, 674–682 (1992). https://doi.org/10.2165/00003495-199243050-00004

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  • DOI: https://doi.org/10.2165/00003495-199243050-00004

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