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Cyclosporin for Crohn’s Disease?

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References

  • Allison MC, Pounder RE. Cyclosporin for Crohns’ disease. Alimentary Pharmacology and Therapeutics 1: 39–43, 1987

    Article  PubMed  CAS  Google Scholar 

  • Ardizzone S, Fasoli R, Sangaletti O, Petrillo M, Bianchi Porro G. The treatment of chronically active Crohn’s disease with cyclosporin A. Current Therapeutic Research 48: 1–4, 1980

    Google Scholar 

  • Baker K, Jewell DP. Cyclosporin for the treatment of severe inflammatory bowel disease. Alimentary Pharmacology and Therapeutics 3: 143–149, 1989

    Article  PubMed  CAS  Google Scholar 

  • Brynskov J, Freund L, Rasmussen SN, Lauritsen K, de Muckadell OS, et al. A placebo-controlled, double-blind randomized trial of cyclosporine therapy in active chronic Crohn’s disease. New England Journal of Medicine 321: 845–850, 1989

    Article  PubMed  CAS  Google Scholar 

  • Brynskov J, Freund L, Rasmussen SN, Lauritsen K, de Muckadell OS, et al. Final report on a placebo-controlled, double-blind, randomized, multicentre trial of cyclosporin treatment in active chronic Crohn’s disease. Scandinavian Journal of Gastroenterology 26: 689–695, 1991

    Article  PubMed  CAS  Google Scholar 

  • Brynskov J, Thomsen H, Nielsen SL. Renographic monitoring of renal function in patients with Crohn’s disease treated with low dose cyclosporin: a controlled study. British Medical Journal 300: 1438–1439, 1990

    Article  PubMed  CAS  Google Scholar 

  • Fukushima T, Sugita A, Masuzawa S, Yamazaki Y, Tsuchiya S. Effects of cyclosporin A on Crohn’s active disease. Gastroen-terologia Japonica 24: 12–15, 1989

    CAS  Google Scholar 

  • Harris DT, Kozumbo WJ, Cerutti PA, Cerottini JC. Mechanisms of cyclosporin A-induced immunosuppression. Cellular Immunology 109: 104–114, 1987

    Article  PubMed  Google Scholar 

  • Lobo AJ, Juby LD, Axon ATR. Cyclosporine in Crohn’s disease. New England Journal of Medicine 322: 636, 1990

    Article  Google Scholar 

  • Lobo AJ, Juby LD, Rothwell J, Poole TW, Axon ATR. Long-term treatment of Crohn’s disease with cyclosporine: the effect of a very low dose on maintenance of remission. Journal of Clinical Gastroenterology 13: 42–45, 1991

    Article  PubMed  CAS  Google Scholar 

  • Lofberg R, Angelin B, Einarsson K, Gabrielsson N, Ost L. Unsatisfactory effect of cyclosporin A treatment in Crohn’s disease: a report of five cases. Journal of Internal Medicine 226: 157–161, 1989

    Article  PubMed  CAS  Google Scholar 

  • Mitchell IC, Turk JL. Effect of the immunemodulating agents cyclophosphamide, methotrexate, hydrocortisone and cyclosporin A on an animal model of granulomatous bowel disease. Gut 31: 674–678, 1990

    Article  PubMed  CAS  Google Scholar 

  • Parrott NR, Taylor RMR, Venables CW, Record OC. Treatment of Crohn’s disease in relapse with cyclosporin A. British Journal of Surgery 75: 1185–1188, 1988

    Article  PubMed  CAS  Google Scholar 

  • Peltekian KM, Williams CN, MacDonald AS, Roy PD, Czolpinska E. Open trial of cyclosporine in patients with severe active Crohn’s disease refractory to conventional therapy. Canadian Journal of Gastroenterology 2: 5–11, 1988

    Google Scholar 

  • Ranzi T, Campanini MC, Quarto di Palo F, Velio P, Bianchi PA. Cyclosporin A in Crohn’s disease. Current Therapeutic Research 45: 245–252, 1989

    Google Scholar 

  • Sachar DB. Cyclosporin in Crohn’s disease. New England Journal of Medicine 322: 637, 1990

    Article  Google Scholar 

  • Stange EF, Fleig WE, Rehklau E, Ditschuneit H. Cyclosporin A treatment in inflammatory bowel disease. Digestive Diseases and Sciences 34: 1387–1392, 1989

    Article  PubMed  CAS  Google Scholar 

  • Summers RW, Switz DM, Sessions Jr JT, Becktel JM, Best WR, et al. National cooperative Crohn’s disease study: results of drug treatment. Gastroenterology 77: 847–869, 1979

    PubMed  CAS  Google Scholar 

  • Thomson AW, Neild GH. Cyclosporin: use outside transplantation. British Journal 302: 4–5, 1991

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Gastroenterology Unit, S. Raffaele Hospital, University of Milan, Milan, Italy

    Mario Guslandi & A. Tittobello

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  1. Mario Guslandi
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  2. A. Tittobello
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Guslandi, M., Tittobello, A. Cyclosporin for Crohn’s Disease?. Drugs 43, 440–442 (1992). https://doi.org/10.2165/00003495-199243040-00002

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  • DOI: https://doi.org/10.2165/00003495-199243040-00002

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