Skip to main content

Advertisement

SpringerLink
Log in

Round-Table Discussion

  • Published:
Drugs Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Anwer MS, Engelkind LR, Nolan K, Sullivan D, Zimniak P, et al. Hepatotoxic bile acids increase cyostolic Ca++ activity of isolated rat hepatocytes. Hepatology 8: 887–891, 1988

    Article  PubMed  CAS  Google Scholar 

  • Baldessarini RJ. Neuropharmacology of 5-adenosyl-L-methionine. American Journal of Medicine 83(Suppl. 5A): 95–103, 1987

    Article  PubMed  CAS  Google Scholar 

  • Batlle AM del C. Lead intoxication and acute porphyria: development and positive experience in their therapy. In Nordmann Y (Ed.) Porphyrins and porphyrias, pp. 189–200, Libbey Eurotext, London, 1986

    Google Scholar 

  • Batlle AM del C, Paredes SR, Fukuda H, Kozicki PA, Rossetti MV. S-adenosyl-L-methionine, a mechanism for its action on lead mobilization and disposal in lead poisoning. Biochemical Archives 2: 293–303, 1986

    CAS  Google Scholar 

  • Batlle AM del C, Stella AM, DeKaminsky AR, Kaminsky C, Mariano HG. Two cases of infantile porphyria cutanea tarda: successful treatment with oral S-adenosyl-L-methionine and low-dose oral chloroquine. British Journal of Dermatology 116: 407–415, 1987

    Article  Google Scholar 

  • Batlle A, Stella AM, Melito V, Gomez HL, Pietropaolo N, et al. Erythropoietic protoporphyria and S-adenosyl-L-methionine. International Journal of Biochemistry, in press

  • Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. American Journal of Medicine 83(Suppl. 5A): 84–88, 1987

    Article  PubMed  CAS  Google Scholar 

  • Bonfirraro G, Chieffi O, Quinti R, Tedesco R, Le Grazie C, et al. S-adenosyl-L-mcthionine (SAMe)-induced amelioration of intrahepatic cholestasis of pregnancy. Results of an open study. Drug Investigation 2: 125–128, 1990

    Google Scholar 

  • Cantoni L, Budillon G, Cuomo R, Rodinò S, Le Grazie C, et al. Protective effect of S-adenosyl-L-methionine in hepatic uroporphyria. Evaluation in an experimental model. Scandinavian Journal of Gastroenterology 25: 1039–1040, 1990

    Article  Google Scholar 

  • Combettes L, Berthon B, Doucet E, Erlinger S, Claret M. Characteristics of bile acid-mediated Ca2+ release from permeabilized liver cells and liver microsomes. Journal of Biological Chemistry 264: 157–167, 1989

    PubMed  CAS  Google Scholar 

  • Crabb DW. Biological markers for increased risk of alcoholism and for quantitation of alcohol consumption. Journal of Clinical Investigation 85: 311–315, 1990

    Article  PubMed  CAS  Google Scholar 

  • Crivelli O, Lavarini C, Chiaberge E, et al. Microsomal autoantibodies in chronic infections with the HBsAg associated delta (δ) agent. Clinical and Experimental Immunology 54: 232–238, 1983

    PubMed  CAS  Google Scholar 

  • Cuomo R, Rodinò S, Cantoni L, Rizzoli R, Simoni P, et al. Bile and biliary lipid secretion in rats with hexachlorobenzene-induced porphyria. Effect of S-adenosyl-L-methionine administration. Journal of Hepatology, in press

  • Everson GT, Ahnen D, Harper PC, Krawitt EL. Benign recurrent intrahepatic cholestasis: treatment with S-adenosylmethionine. Gastroenterology 96: 1354–1357, 1989

    PubMed  CAS  Google Scholar 

  • Farrell GC, Duddy SK, Kass GEN, Liopis J, Gahm A, et al. Release of Ca2+ from the endoplasmic reticulum is not the mechanism for bile acid-induced cholestasis and hepatotoxicity in the intact rat liver. Journal of Clinical Investigation 85(4): 1255–1259, 1990

    Article  PubMed  CAS  Google Scholar 

  • Fazio C, Andreoli V, Agnoli A, Cassacchia M, Cerbo R. Effecti terapeutici e meccanismo d’azione della S-adenosil-L-metionina (SAMe) nella sindromi depressive. Minerva Medica 64: 1515–1529, 1973

    PubMed  CAS  Google Scholar 

  • Frezza M, Di Padova C, Pozzato G, Terpin M, Baraona E, et al. High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. New England Journal of Medicine 322: 95–99, 1990

    Article  PubMed  CAS  Google Scholar 

  • Frezza M, Pozzato G, Chiesa L, Stramentinoli G, Di Padova C. Reversal of intrahepatic cholestasis of pregnancy in women after high dose S-adenosyl-L-methionine administration. Hepatology 4: 274–278, 1984

    Article  PubMed  CAS  Google Scholar 

  • Frezza M, Surrenti C, Manzillo G, Fiaccadori F, Bortolini M, et al. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology 99: 211–215, 1990

    PubMed  CAS  Google Scholar 

  • Fricker G, Landmann L, Meier PJ. Ethinylestradiol (EE) induced structural and functional alterations of rat liver plasma membranes and their, reversal by S-adenosylmethionine (SAMe) in vitro. Hepatology 8: 1224, 1988

    Google Scholar 

  • Fricker G, Landmann L, Meier PJ. Extra-hepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocytes. Journal of Clinical Investigation 84: 876–885, 1989

    Article  PubMed  CAS  Google Scholar 

  • Goedde HW, Agarwal DP. Polymorphism of aldehyde dehydrogenase and alcohol sensitivity. Enzyme 37: 29–44, 1987

    PubMed  CAS  Google Scholar 

  • Hagenbuch B, Lübbert H, Stieger B, Meier PJ. Expression of the hepatocyte Na+/bile acid cotransporter in Xenopus laevis oocytes. Journal of Biological Chemistry 265: 5357–5360, 1990

    PubMed  CAS  Google Scholar 

  • Hong WJ, Petell JK, Swank D, Sanford J, Hixson DC, et al. Expression of dipeptidyl peptidase IV in rat tissues is mainly regulated at the mRNA levels. Experimental Cell Research 182: 256–266, 1989

    Article  PubMed  CAS  Google Scholar 

  • Jackson PA, Morgan DB. The relationship between membrane cholesterol and phospholipid and sodium efflux in erythrocytes from healthy subjects and patients with chronic cholestasis. Clinical Science 62: 104–107, 1982

    Google Scholar 

  • James DFW. Ursodeoxycholic acid treatment for chronic cholestatic liver disease. Journal of Hepatology 11: 5–8, 1990

    Article  PubMed  CAS  Google Scholar 

  • Kamimoto Y, Gatmaitan Z, Hsu J, Arias IM. The function of Gp 170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles. Journal of Biological Chemistry 264: 11693–11698, 1989

    PubMed  CAS  Google Scholar 

  • Koga Y. Anticholestatic and cytoprotective properties of ursodeoxycholic acid — studies in vivo and in vitro. Acta Hepatologica Japonica 28: 1597–1604, 1987

    Article  CAS  Google Scholar 

  • Lafuenti G, Plotti G, Nicolanti G, Caruso A, Tibollo FG, et al. Valutazione delle modificazioni di parametri clinici e biochimici in gravide con colestasi in terapia con S-adenosyl-l-methionine per os. Giornale Italiano Ostetricia e Ginecologia 5: 357–361, 1988

    Google Scholar 

  • Lenzi M, Ballardini G, Fusconi M, Cassani F, Selleri L, et al. Type 2 autoimmune hepatitis and hepatitis C virus infection. Lancet 335: 258–259, 1990

    Article  PubMed  CAS  Google Scholar 

  • Lieber CS, Casini A, De Carli LM, Kim C-I, Lowe N, et al. S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon. Hepatology 11: 165–172, 1990

    Article  PubMed  CAS  Google Scholar 

  • Lin SH, Guidotti G. Cloning and expression of a cDNA coding for a rat liver plasma membrane ecto-ATPase. The primary structure of the ecto-ATPase is similar to that in the human biliary glycoprotein I. Journal of Biological Chemistry 264: 14408–14414, 1989

    PubMed  CAS  Google Scholar 

  • McFarlane IG, Smith HM, Johnson PJ, Bray GP, Vergani D, et al. Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false positive result? Lancet 1: 754–757, 1990

    Article  Google Scholar 

  • Muriel P, Mourelle M. Prevention and reversion of erythrocyte membrane alterations in cirrhosis by S-adenosylmethionine. Hepatology 10: 742, 1989

    Google Scholar 

  • Rafique S, Guardascione M, Burroughs AK, Owen JS. S-Adenosylmethionine (SAMe) reduces cholesterol deposition in erythrocyte membranes of cirrhotic patients. Journal of Hepatology 11(2): S51, 1990

    Article  Google Scholar 

  • eichen J, Berr F, Le M, Warren GH. Characterization of calcium deprivation-induced cholestasis in the perfused rat liver. American Journal of Physiology 249: G48–G57, 1985

    Google Scholar 

  • Schachter D. Fluidity and function of hepatocyte plasma membranes. Hepatology 4: 140–151, 1984

    Article  PubMed  CAS  Google Scholar 

  • Scharschmidt BF, Lake JR. Hepatocellular bile acid transport and ursodeoxycholic acid hypercholeresis. Digestive Diseases and Sciences 34 (Suppl.): 5S–15S, 1989

    Article  PubMed  CAS  Google Scholar 

  • Schölmerich J, Baumgartner U, Miyoi K, Gerok W. Taurourso-deoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver. Journal of Hepatology 10: 280–283, 1990

    Article  PubMed  Google Scholar 

  • Schreiber AJ, Simon FR. Estrogen-induced cholestasis: clues to pathogenesis and treatment. Hepatology 3: 607–613, 1983

    Article  PubMed  CAS  Google Scholar 

  • Scott PD, Knoop M, McMahon RT, Braganza JM, Hutchinson IV. Usefulness of sulphadenosylmethionine (SAMe) in a transplant model of acute haemorrhagic pancreatitis (AHP). Digestion 46: 176–177, 1990

    Google Scholar 

  • Sellinger M, Boyer JL. Physiology of bile secretion and cholestatis. Progress in Liver Diseases 9: 237–259, 1990

    PubMed  CAS  Google Scholar 

  • Stammler L, Reichen J, Oehler R, Bianchi L, Landmann L. Decreased hepatocellular volume and intact morphology of tight junctions in calcium deprivation-induced cholestasis. Journal of Hepatology 10: 318–326, 1990

    Article  PubMed  CAS  Google Scholar 

  • Stramentinoli G. Pharmacologic aspects of S-adenosyl methionine. American Journal of Medicine 83(Suppl. 5A): 35–42, 1987

    Article  PubMed  CAS  Google Scholar 

  • Stramentinoli G, Gualano M, Galli-Kienle M. Intestinal absorption of S-adenosyl-L-methionine. Journal of Pharmacology and Experimental Therapeutics 209: 323–326, 1979

    PubMed  CAS  Google Scholar 

  • Stricker & Spoelstra (Eds) Drug-induced hepatic injury, Elsevier, Amsterdam, 1985

    Google Scholar 

  • Thomas CE, Reed DJ. Current status of calcium in hepatocellular injury. Hepatology 10: 375–384, 1989

    Article  PubMed  CAS  Google Scholar 

  • Tolbert LC. MAT kinetics in affective disorders and schizophrenia. An account. Alabama Journal of Medical Science 25: 291–296, 1988

    CAS  Google Scholar 

  • Traver J, Varela I, Mato JM. Effect of exogenous S-adenosyl-L-methionine on phosphatidylcholine synthesis by isolated rat hepatocytes. Biochemical Pharmacology 33: 1562–1564, 1984

    Article  PubMed  CAS  Google Scholar 

  • Vendemiale G, Altomare E, Trizio T, Le Grazie C, Di Padova C, et al. Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease. Scandinavian Journal of Gastroenterology 24(4): 407–415, 1989

    Article  PubMed  CAS  Google Scholar 

  • von Dippe P, Levy D. Expression of the bile acid transport protein during liver development and in hepatoma cells. Journal of Biological Chemistry 265: 5942–5945, 1990

    Google Scholar 

  • Yoshida T, Bonkovsky H, Ansari A, Danner D. Antibodies against mitochondrial dehydrogenase complexes in primary biliary cirrhosis. Gastroenterology 99: 187–194, 1990

    PubMed  CAS  Google Scholar 

  • Yoshihara H, Sato N, Kamada T, Abe H. Low Km ALDH isozymes and alcoholic liver injury. Pharmacology, Biochemistry and Behaviour 18(Suppl. 1): 425–428, 1983

    Article  Google Scholar 

  • Zimmermann HJ, Lewis JH. Drug induced cholestasis. Medical Toxicology 2: 112–160, 1987

    Google Scholar 

Download references

Rights and permissions

Reprints and permissions

About this article

Cite this article

Round-Table Discussion. Drugs 40 (Suppl 3), 129–138 (1990). https://doi.org/10.2165/00003495-199000403-00013

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00003495-199000403-00013

Keywords

Search

Navigation