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Maternal and Fetal Cardiovascular Changes After Intravenous Injections of Isradipine to Pregnant Women

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Conclusion

The results suggest that isradipine might be a suitable drug for antihypertensive treatment in pregnancy. Intravenous bolus injections had no adverse effects on fetal circulation and, in contrast to other calcium antagonists of a similar type, had little effect on uterine activity. Doses of isradipine 0.3mg promptly normalised blood pressure in hypertensive pregnant women.

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References

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  • Wide-Swensson D, Ingemarsson I, Arulkumaran S, Andersson K-E. Effects of isradipine, a new calcium antagonist, on maternal cardiovascular system and uterine activity in labour. British Journal of Obstetrics and Gynaecology, in press

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Authors and Affiliations

  1. Departments of Obstetrics and Gynaecology, University of Lund, Lund, Sweden

    I. Ingemarsson & D. Wide-Swensson

  2. Department of Clinical Pharmacology, University of Lund, Lund, Sweden

    K. -E. Andersson

  3. National University of Singapore, Singapore, Malaysia

    S. Arulkumaran

Authors
  1. I. Ingemarsson
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  2. D. Wide-Swensson
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  3. K. -E. Andersson
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  4. S. Arulkumaran
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Ingemarsson, I., Wide-Swensson, D., Andersson, K.E. et al. Maternal and Fetal Cardiovascular Changes After Intravenous Injections of Isradipine to Pregnant Women. Drugs 40 (Suppl 2), 58–59 (1990). https://doi.org/10.2165/00003495-199000402-00014

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  • DOI: https://doi.org/10.2165/00003495-199000402-00014

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