Skip to main content
Log in

A New Selective Antagonist of Vascular Serotonin Receptors Lowers Blood Pressure in Spontaneously Hypertensive Rats

  • Short Communication
  • Poster Presentations: Pharmacology of Serotonin Antagonists
  • Published:
Drugs Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Arunlakshana O, Schild HO. Some quantitative uses of drug antagonism. British Journal of Pharmacology 14: 48–58, 1959

    CAS  Google Scholar 

  • De Crée J, Leempoels J, Geukens H, De Cock W, Verhaegen H. The antihypertensive effect of ketanserin (R 41 468) a novel 5-HT blocking agent, in patients with essential hypertension. Clinical Science 61: 473s–476s, 1981

    PubMed  Google Scholar 

  • Fozard JR. Mechanism of the hypotensive effect of ketanserin. Journal of Cardiovascular Pharmacology 4: 829–838, 1982

    Article  PubMed  CAS  Google Scholar 

  • Vanhoutte PM. Serotonin and the cardiovascular system, Raven Press, New York, 1985

    Google Scholar 

  • Van Nueten JM, Janssen PAJ, Van Beek J, Xhonneux R, Verbeuren TJ, et al. Vascular effects of ketanserin (R 41 468), a novel antagonist of 5-HT serotonergic receptors. Journal of Pharmacology and Experimental Therapeutics 218: 217–230, 1981

    PubMed  Google Scholar 

  • Waud DR, Parker RB. Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation II. Competitive antagonists. Journal of Pharmacology and Experimental Therapeutics 177: 13–24, 1971

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Salvati, P., Vaghi, F., Colombo, M. et al. A New Selective Antagonist of Vascular Serotonin Receptors Lowers Blood Pressure in Spontaneously Hypertensive Rats. Drugs 36 (Suppl 1), 105–109 (1988). https://doi.org/10.2165/00003495-198800361-00019

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00003495-198800361-00019

Keywords

Navigation