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Sulbactam and Clavulanic Acid: Studies of Enzyme Kinetics and Synergy with Ampicillin and Mezlocillin

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References

  • Buschcr K.H., Cullmann W., Dick W., Stieglitz M. Selection frequency of resistant variants by various β-lactam antibiotics in clinical Enterobacter cloacae isolates. Chemotherapy 33: 40–51. 1987

    Article  Google Scholar 

  • Cullmann W., Dick W. Investigations on β-lactamase stability of recently developed β-lactam compounds: study of enzyme kinetics. Zentralblatt fur Bakteriologie und Hygiene. I. Abteilung Originale A 254: 413–422. 1983

    CAS  Google Scholar 

  • Cullmann W., Stieglitz M. Das Antibiotikum Aztrconam: Untersuchungen zur plasmidbedingtcn Resistenzausbildung. Immunität und Infektion 11: 30–34. 1983

    PubMed  CAS  Google Scholar 

  • Cullmann W., Dalhoff A., Dick W. Nonspecific induction of β-lactamase in Enterobacter cloacae. Journal of General Microbiology 130: 1781–1786. 1984

    PubMed  CAS  Google Scholar 

  • Fisher J., Charnas RL., Knowles JR. Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid. Biochemistry 17: 2180–2184. 1978

    Article  PubMed  CAS  Google Scholar 

  • Fisher J., Charnas RL., Bradley SM., Knowles JR. Inactivation of the RTEM β-lactamase from Escherichia coli. Interaction of penam sulfones with enzyme. Biochemistry 20: 2726–2731, 1981

    Article  PubMed  CAS  Google Scholar 

  • Hartman BJ., Tomasz A. Low affinity penicillin-binding protein associated with β-lactam resistance in Staphylococcus aureus. Journal of Bacteriology 158: 513–516. 1984

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Medical Microbiology, Ruhr University, Bochum, D-4630

    W. Cullmann, M. Stieglitz & W. Opferkuch

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  1. W. Cullmann
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  2. M. Stieglitz
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  3. W. Opferkuch
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Cullmann, W., Stieglitz, M. & Opferkuch, W. Sulbactam and Clavulanic Acid: Studies of Enzyme Kinetics and Synergy with Ampicillin and Mezlocillin. Drugs 35 (Suppl 7), 71–76 (1988). https://doi.org/10.2165/00003495-198800357-00016

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  • DOI: https://doi.org/10.2165/00003495-198800357-00016

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