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Importance of β- Lactamases and Clinical Implications of their Inhibitors

  • Problems of Resistance in clinical Infection
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Summary

The production of β- lactamases has constituted the main line of defence of bacteria exposed to β- lactam antibiotics. β- Lactamases may be part of the natural constitution of the cell, acquired by DNA transferred from other bacteria or induced by exposure to a β- lactam antibiotic. Many different types of β- lactamases have been described in a variety of bacteria.

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References

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Authors and Affiliations

  1. Department of Medical Microbiology, The London Hospital Medical College, University of London, London, E1 2AD, England

    J. D. Williams

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  1. J. D. Williams
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Williams, J.D. Importance of β- Lactamases and Clinical Implications of their Inhibitors. Drugs 35 (Suppl 7), 3–11 (1988). https://doi.org/10.2165/00003495-198800357-00003

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  • DOI: https://doi.org/10.2165/00003495-198800357-00003

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