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Effects of Enalapril on Different Aspects of the Clinical State in Congestive Heart Failure

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Summary

In patients with moderate to severe CHF, enalapril improves symptoms and is well tolerated. It increases functional capacity in the form of exercise time and reduces the left ventricular dimensions. Enalapril also has favourable effects on electrolytes and, although it increases renal blood flow, it reduces the glomerular filtration rate.

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References

  • Cleland JGF, Dargie HJ, Gillen G, et al. Effects of enalapril in heart failure: a double blind study of effects on exercise performance, renal function, hormones and metabolic state. British Heart Journal 54: 305, 1985

    Article  PubMed  CAS  Google Scholar 

  • Cleland JGF, Dargie HJ, Hodsman P, et al. Captopril in heart failure: a double blind study. British Heart Journal 52: 530, 1984

    Article  PubMed  CAS  Google Scholar 

  • Cleland JGF, Dargie HJ, Gillen G, et al. Captopril in heart failure: a double-blind study of the effects on renal function. Journal of Cardiovascular Pharmacology 8: 700, 1986

    PubMed  CAS  Google Scholar 

  • Franciosa JA, Wilen M, Zieschi S, Cohn JN. Survival in men with severe chronic left ventricular failure due to either coronary heart disease or idiopathic dilated cardiomyopathy. American Journal of Cardiology 51: 831, 1983

    Article  PubMed  CAS  Google Scholar 

  • Hall JE, Deighton AC, Jackson TE, et al. Control of glomerular filtration rate by the renin angiotensin system. American Journal of Physiology 5: 366–372, 1977

    Google Scholar 

  • Peach MJ. Renin angiotensin system: biochemistry and mechanism of action. Physiological Reviews 57: 313, 1977

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. MRC Blood Pressure Unit, Western Infirmary, Glasgow, G11 6NT, Scotland

    H. J. Dargie

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  1. H. J. Dargie
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Dargie, H.J. Effects of Enalapril on Different Aspects of the Clinical State in Congestive Heart Failure. Drugs 32 (Suppl 5), 45–49 (1986). https://doi.org/10.2165/00003495-198600325-00007

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  • DOI: https://doi.org/10.2165/00003495-198600325-00007

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