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An Open Comparison of Amiodarone with Diltiazem and Glyceryl Trinitrate in Patients with Stable Exertional Angina

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Summary

The haemodynamic and electrocardiographic effects of amiodarone, diltiazem, and glyceryl trinitrate (nitroglycerin) were compared in an open study of 18 patients with stable exertional angina using a graded treadmill exercise test, Amiodarone and diltiazem exerted similar antianginal effectiveness as assessed by increases in exercise performance and duration of exercise, as well as decreases in ST-segment depression, The antianginal efficacy of glyceryl trinitrate was somewhat lower than that of the other 2 agents, All the drugs were well tolerated

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Authors and Affiliations

  1. Department of Cardiology, University Hospital, Amiens

    J. P. Lesbre & J. P. Eloy

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  1. J. P. Lesbre
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  2. J. P. Eloy
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Amiodarone is marketed by Sanofi Labaz under the trademarks Cordarone (France), Cordarex (Germany), Cordarone-X (UK), Trangorex (Spain), Amiodar (Italy)

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Lesbre, J.P., Eloy, J.P. An Open Comparison of Amiodarone with Diltiazem and Glyceryl Trinitrate in Patients with Stable Exertional Angina. Molecular Diagnosis 29 (Suppl 3), 31–36 (1985). https://doi.org/10.2165/00003495-198500293-00005

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  • DOI: https://doi.org/10.2165/00003495-198500293-00005

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