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State-of-the-Art: Comparative Pharmacology of the β-Adrenoceptor Blocking Drugs

  • Section 2A: Pharmacodynamics, Pharmacokinetics and Drug Interactions
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Summary

There are certain pharmacological differences among the many β- adrenoceptor blocking drugs (β- blockers) available today. These properties may influence the clinical selection of a β- blocker and include cardioselectivity, partial agonist activity, membrane stabilising activity and lipophilicity. These properties are reviewed to assess their relevance and relative importance in clinical and experimental situations.

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Authors and Affiliations

  1. Burroughs Wellcome Scholar in Clinical Pharmacology, Division of Clinical Pharmacology, Duke University Medical Center, Durham, N.C., 27710, USA

    David G. Shand

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  1. David G. Shand
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Shand, D.G. State-of-the-Art: Comparative Pharmacology of the β-Adrenoceptor Blocking Drugs. Drugs 25 (Suppl 2), 92–99 (1983). https://doi.org/10.2165/00003495-198300252-00031

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  • DOI: https://doi.org/10.2165/00003495-198300252-00031

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