Skip to main content
SpringerLink
Log in

Experience with β-Adrenoreceptor Blockers in Hypertension

  • Session VII: Use of β-Adrenoreceptor Blocking Drugs in Hypertension
  • Chairman: Dr G.S.M. Kellaway (Auckland)
  • Published:
Drugs Aims and scope Submit manuscript

Summary

At the Dunedin Hypertension Clinic β-blockers are the drugs of choice for most hypertensive patients, usually in combination with diuretics (especially in older subjects) and often with other drugs in the more severe cases. All β-blockers have an antihypertensive effect, regardless of other characteristics (e.g. cardio-selectivity, instrinsic sympathomimetic effect, or membrane activity). d-Propranolol has no significant effect on blood pressure. β-Blockers do not prevent stress-induced (mental arithmetic) rises in blood pressure in hypertensive subjects though the level of blood pressure reached during stress tends to be lower because the base line is lower. Twice-daily dosage of β-blockers is usually satisfactory.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Olsson, S.B. and Varnauskas, F.: Duration of betareceptor blockade after oral administration of LB-46. European Journal of Clinical Pharmacology 5: 214 (1973).

    Article  CAS  Google Scholar 

  • Waal-Manning, HJ.: Propranolol-induced depression. British Medical Journal 2: 50 (1967).

    Article  Google Scholar 

  • Waal-Manning, H.J.: Comparative studies on the hypotensive effects of beta-adrenergic receptor blockers; in Simpson (Ed.) Beta-adrenergic Receptor Blocking Drugs, p.64–72, Ciba Symposium, Auckland 1970 (Australasian Drug Information Services, Auckland 1970).

    Google Scholar 

  • Waal-Manning, H.J. and Simpson, F.O.: Pindolol: A comparison with other antihypertensive drugs and a double-blind placebo trial. New Zealand Medical Journal 80: 151–157 (1974).

    PubMed  CAS  Google Scholar 

  • Waal-Manning, H.J. and Simpson, F.O.: Paradoxical effect of pindolol. British Medical Journal 2: 155–156 (1975).

    Article  Google Scholar 

  • Waal-Manning, H.J. and Wood, A.J.: Pindolol in hypertension: Twice-daily versus thrice-daily dosage. Medical Journal of Australia 2: 274–275 (1975).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Wellcome Medical Research Institute, Department of Medicine, University of Otago Medical School, P.O. Box 913, Dunedin, New Zealand

    Hendrika J. Waal-Manning

Authors
  1. Hendrika J. Waal-Manning
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Waal-Manning, H.J. Experience with β-Adrenoreceptor Blockers in Hypertension. Drugs 11 (Suppl 1), 164–171 (1976). https://doi.org/10.2165/00003495-197600111-00034

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00003495-197600111-00034

Keywords

Search

Navigation