Beclomethasone Dipropionate: II: Allergic Rhinitis and Other Conditions

Summary

At doses similar to those used in the treatment of chronic bronchial asthma, intranasal beclomethasone dipropionate is effective in alleviating nasal symptoms of seasonal allergic and perennial rhinitis in about three-quarters of patients. Eye symptoms are not relieved. The carry-over effect of the evening dose is useful in preventing early morning attacks of sneezing. Intranasal beclomethasone dipropionate is useful in controlling symptoms persisting after polypectomy and may possibly delay or eliminate the need for the surgical removal of nasal polyps, which may shrink after several weeks or months of treatment.

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Correspondence to R. N. Brogden or R. M. Pinder or Phyllis R. Sawyer or T. M. Speight or G. S. Avery.

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Manuscript reviewed by: H.M. Brown, Derby Chest Clinic, Derby, England; T.J.H. Clark, Guy’s Hospital, London, England; C. Collins-Williams, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada; E.A. Espiner, Christchurch Clinical School, Department of Medicine, The Princess Margaret Hospital, Christchurch, New Zealand; W. Franklin, Allergy Unit, Massachusetts General Hospital, Boston, USA; G.J. Gibson, Royal Postgraduate Medical School, University of London, Hammersmith Hospital, London, England; I.W.B. Grant, Respiratory Unit, Northern General Hospital, Edinburgh, Scotland; S. Lal, Bury Area Health Authority, Bury General Hospital, Lancashire, England; J.B. Mackay, Chest Department, Wellington Hospital, Wellington, New Zealand; T. Miyamoto, Faculty of Medicine, University of Tokyo, Tokyo, Japan; N. Mygind, Otopathological Laboratory, University ENT Department, Rigshospitalet, Copenhagen, Denmark; T.V. O’Donnell, Department of Medicine, Wellington Hospital, Wellington, New Zealand; M. Turner-Warwick, Cardiothoracic Unit, University of London, London, England; R. Vandenberg, The Royal North Shore Hospital of Sydney, Sydney, NSW, Australia; J. Vilsvik, Lungeavdelingen, Regionsykehuset i Trondheim, Norway; M. Weston, Cameron Wing, St. Vincent’s Hospital, Darlinghurst, NSW, Australia

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Brogden, R.N., Pinder, R.M., Sawyer, P.R. et al. Beclomethasone Dipropionate: II: Allergic Rhinitis and Other Conditions. Drugs 10, 211–217 (1975). https://doi.org/10.2165/00003495-197510030-00003

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Keywords

  • Rhinitis
  • Allergic Rhinitis
  • Nasal Polyp
  • Beclomethasone
  • Sodium Cromoglycate