Skip to main content
SpringerLink
Log in

Hexachlorophane and Skin Care of Newborn Infants

  • Special Article
  • Published:
Drugs Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • American Academy of Pediatrics: Committee on Fetus and Newborn, Hexachlorophene and skin care of newborn infants. Pediatrics 49: 625 (1972).

    Google Scholar 

  • Alder, V.D.; Burman, D.; Coroner, Beryl D. and Gillespie, W.A.: Absorption of hexachlorophene from infants’ skin. Lancet 2: 384 (1972).

    Article  PubMed  CAS  Google Scholar 

  • Cunningham, M.D.: The growth and development of new-borns with known hexachlorophene levels. Paper read at the American Academy of Paediatrics Meeting at the Hilton Hotel in New York on October 19 (1972).

  • Curley, A. and Hawk, R.E.: Hexachlorophene I. Analysis in body fluids and tissues of experimental animals. Paper read at the 161st National Meeting of the American Chemical Society, in Los Angeles, California, March 28 to April 2 (1971).

  • Curley, A.; Hawk, R.E.; Kimbrough, R.D.; Nathenson, G. and Finberg, L.: Dermal absorption of hexachlorophene in infants. Lancet 2: 296 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Curley, A; Hawk, R.E. and Under, R.E.: Hexachlorophene II. Percutaneous absorption in rabbits. Presented at the 161st National Meeting of the American Chemical Society, in Los Angeles, California, March 28 to April 2 (1971).

  • Dewar, J.; Porter, I.A. and Smylie, H.G.: Staphylococcal infection in cervical glands of infants. Lancet 2: 712 (1972).

    Article  PubMed  CAS  Google Scholar 

  • Edwards, C.C.: Food and Drug Administration, Press Conference, September 22 (1972).

  • Food and Drugs: Hexachlorophene as a component in drug and cosmetic products for human use. Federal Register 37: 20160 (1972).

    Google Scholar 

  • Gaines, T.B. and Kimbrough, R.D.: Paper read at the Tenth Annual Meeting of the Society of Toxicology in Washington DC, March 7 to 11 (1971).

  • Gandolfi, A.J.; Dost, F.N. and Buhler, D.R.: Absorption, excretion and metabolism of hexachlorophene in the rat and rabbit. Paper read at the 56th Annual Meeting of the Federation of American Societies for Experimental Biology, at Atlantic City, New Jersey, April 9 to 14 (1972).

  • Gump W.S.: Dihydroxyhexachlorodiphenyl methane and method of producing same. US Patent number 2,250,480 (1941).

  • Gump, W.S.: Toxicological properties of hexachlorophene. Journal of the Society of Cosmetic Chemists 20: 173 (1969).

    CAS  Google Scholar 

  • Hart, E.R.: Toxicity of pHisoHex on 90-day skin applications to infant rhesus monkeys. Report submitted to Sterling-Winthrop Research Institute by Bionetics Research Laboratories, December 3 (1971).

  • Herter, W.B.: Hexachlorophane poisoning. Kaiser Foundation Medical Bulletin 7: 228 (1959).

    Google Scholar 

  • Hills, S.: The isolation of Cl. tetani from infected talc. New Zealand Medical Journal 45: 419 (1946).

    PubMed  CAS  Google Scholar 

  • Industrial Bio-Test Laboratories Inc.: Report to Givaudan Corporation: Persistence of hexachlorophene in blood of rats following 14 days of hexachlorophene treatment (1971a).

  • Industrial Bio-Test Laboratories Inc.: Report to Givuadan Corporation: Distribution and excretion study of hexachlorophene following dermal application to a rhesus monkey (1971b).

  • Jones, R.: Tetanus Neonatorum: A report of three cases. New Zealand Medical Journal 45: 423 (1946).

    PubMed  CAS  Google Scholar 

  • Kimbrough, R.D. and Gaines, T.B.: Hexachlorophene effects on the rat brain. Archives of Environmental Health 23: 114 (1971).

    PubMed  CAS  Google Scholar 

  • Larson, D.L.: Studies show hexachlorophene causes burn syndrome. Hospitals, JAHA 42: 63 (1968).

    CAS  Google Scholar 

  • Lockhart, J.D.: How toxic is hexachlorophene? Pediatrics 50: 299 (1972a).

    Google Scholar 

  • Lockhart, J.D.: Human adverse reactions associated with hexachlorophene: Summary from FDA Experimental files, September (1972b).

  • Morbidity and Mortality Weekly Report: US Department of Health, Education and Welfare 21: 37 (1972a).

    Google Scholar 

  • Morbidity and Mortality Weekly Report: US Department of Health, Education and Welfare 21: 253 (1972b).

    Google Scholar 

  • Nachman, R.L. and Esterly, Nancy B.: Increased skin permeability in preterm infants. Pediatrics 79: 528 (1971).

    Google Scholar 

  • Pittman, K.A.: Sterling-Winthrop Research Institute, Rensselaer, NY, Inter-Office memo: Plasma hexachlorophene concentrations in monkeys given chronic subcutaneous doses of hexachlorophene, July 16 (1971).

  • Plueckhahn, V.D.: The staphylococcus and the newborn child. British Medical Journal 2: 779 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Plueckhahn, V.D.: Infant antiseptic skin care, blood hexachlorophene concentrations and hexachlorophene neurotoxicity. Conference on hexachlorophene in the nursery, Stowe, Vermont, USA. Paediatrics 51 (Suppl.): 368–382 (1973).

    CAS  Google Scholar 

  • Plueckhahn, V.D.: Infant antiseptic skin care and hexachlorophene. Medical Journal of Australia 1: 93 (1973).

    PubMed  CAS  Google Scholar 

  • Plueckhahn, V.D. and Banks, J.: The ubiquitous staphylococcus. Medical Journal of Australia 1: 664 (1958).

    Google Scholar 

  • Plueckhahn, V.D. and Banks, J.: Hexachlorophene toxicity, the new born child and the staphylococcus. Medical Journal of Australia 1: 897 (1972).

    PubMed  CAS  Google Scholar 

  • Shuman, R.M.; Leech, R.W. and Alvord, E.C.: Neurotoxicity of hexachlorophene in human infants: A histopathologic study of 250 infants. Personal Communication, October 1972.

  • Tremewan, H.C.: Tetanus neonatorum in New Zealand. New Zealand Medical Journal 45: 312 (1946).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, The Geelong Hospital, Victoria, 3220, Australia

    V. D. Plueckhahn (Director)

Authors
  1. V. D. Plueckhahn
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Plueckhahn, V.D. Hexachlorophane and Skin Care of Newborn Infants. Drugs 5, 97–107 (1973). https://doi.org/10.2165/00003495-197305020-00001

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00003495-197305020-00001

Keywords

Search

Navigation