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Rifampicin: A Review

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References

  • Acocella, G.; Nicolis, F.B., and Lamarina, A.: A study on the kinetics of rifampicin in men. Chemotherapia 5: 87 (1967).

    Google Scholar 

  • Annotation. Lancet 1: 976 (1969).

  • Arioli, V.; Pallanza, R.; Furesz, S., and Carniti, G.: Rifampicin: a new rifamycin. 1. Bacteriological studies. Arzneimittel-Forschung 17: 523 (1967).

    PubMed  CAS  Google Scholar 

  • Atlas, E. and Turck, M.: Laboratory and clinical evaluation of rifampicin. American Journal of the Medical Sciences 256: 247 (1968).

    CAS  Google Scholar 

  • Balea, T.; Marche, C., and Marche, J.: Effets hépato-biliaires de l’association rifampicine-isoniazide. Thérapie 25: 125 (1970).

    PubMed  CAS  Google Scholar 

  • Bariffi, F.; DiFilippo, A., and Marinelli, M.: L’attività terapeutica della rifampicina nei processi cronici della tubercolosi polmonare. Archivio di tisiologia e delle malattie dell’apparato respiratorio 23: 329 (1968).

    Google Scholar 

  • Baronti, A. and Lukinovitch, N.: A pilot trial of rifampicin in tuberculosis. Tubercle (Lond.) 49: 80 (1968).

    Google Scholar 

  • Batten, J.: Rifampicin in treatment of experimental tuberculosis in mice. Tubercle (Lond.) 50: 294 (1969).

    CAS  Google Scholar 

  • Becker, Y.; Asher, Y.; Himmel, N., and Zakay-Rones, Z.: Rifampicin inhibition of trachoma agent in vivo. Nature 224: 33 (1969b).

    PubMed  CAS  Google Scholar 

  • Becker, Y. and Zakay-Rones, Z.: Rifampicin: a new antitrachoma drug. Nature 222: 851 (1969a).

    PubMed  CAS  Google Scholar 

  • Ben-Ishai, Z.; Heller, E.; Goldblum, N., and Becker, Y.: Rifampicin poxvirus and trachoma agent. Nature 224: 29 (1969).

    PubMed  CAS  Google Scholar 

  • Blajchman, M.A.; Lowry, R.C.; Pettit, J.E, and Stradling, P.: Rifampicin-induced immune thrombocytopenia. British Medical Journal 3: 24 (1970).

    PubMed  CAS  Google Scholar 

  • Boman, G.; Borgå, O.; Hanngren, Å.; Malmborg, Anna-Stina, and Sjöqvist, F.: Pharmacokinetic interactions between the tuberculostatics rifampicin, para-aminosalicylic acid and isoniazid. Acta Pharmacologica et Toxicologica 28 (suppl. 1): 15 (1970).

    PubMed  CAS  Google Scholar 

  • Boman, G.; Hanngren, Å.; Malmborg, Anna-Stina; Borgå, O., and Sjöqvist, F.: Drug interaction: decreased serum concentrations of rifampicin when given with PAS. Lancet 1: 800 (1971).

    PubMed  CAS  Google Scholar 

  • Brickner, P.W.: Rifampicin: clinical studies with a new antibiotic. Journal of Clinical Pharmacology and New Drugs 9: 243 (1969).

    Google Scholar 

  • Canetti, G.; Le Lirzin, M.; Porven, G.; Rist, N., and Grumbach, F.: Some comparative aspects of rifampicin and isoniazid. Tubercle (Lond.) 49: 367 (1968).

    CAS  Google Scholar 

  • Carratu, L.; Piazza, R., and Massei, V.: The integrity of various organs and systems in patients treated with rifampicin. Archivio di tisiologia e delle malattie dell’apparato respiratorio 22: 463 (1967).

    PubMed  CAS  Google Scholar 

  • Citron, K.M. and May, J.R.: Rifampicin antibiotics in chronic purulent bronchitis. Lancet 2: 982 (1969).

    PubMed  CAS  Google Scholar 

  • Clark, J. and Wallace, A.: The susceptibility of mycobacteria to rifamide and rifampicin. Tubercle (Lond.) 48: 144 (1967).

    CAS  Google Scholar 

  • Cobbold, R.J.C.; Morrison, G.D., and Willcox, R.R.: Treatment of gonorrhoea with single oral doses of rifampicin. British Medical Journal 4: 681 (1968).

    PubMed  CAS  Google Scholar 

  • Cohn, H.D.: Clinical studies with a new rifampicin derivative. Journal of Clinical Pharmacology and New Drugs 9: 118 (1969).

    CAS  Google Scholar 

  • Curci, G. and Loscalzo, B.: Atti del 18mo Congresso Italiano di Tisiologia, Milano 23: 293 (1966).

    Google Scholar 

  • Curci, G.; Ninni, A., and Di Mezza, F.: Indagini sperimentali sulla farmacocinetica della rifampicina. Archivio di tisiologia e delle malattie dell’apparato respiratorio 23: 293 (1968).

    PubMed  CAS  Google Scholar 

  • Daddi, G.; Cornia, F.; Grossi, C.; Perna, G., and Scarpazza, G.: Prime osservazioni sull’attivitá della rifampicina per via orale nella tubercolosi polmonare cronica. Giornale italiano delle malattie del torace 21: 131 (1967).

    PubMed  CAS  Google Scholar 

  • Dans, P.E.; McGehee, R.F.; Wilcox, Claire, and Finland, M.: Rifampicin: Antibacterial activity in vitro and absorption and excretion in normal young men. American Journal of the Medical Sciences 259: 120 (1970).

    PubMed  CAS  Google Scholar 

  • Deal, W.B. and Sanders, E.: Efficacy of rifampicin in treatment of meningococcal carriers. New England Journal of Medicine 281: 641 (1969).

    PubMed  CAS  Google Scholar 

  • De la Roy, Y. de R.; Beauchant, G.; Breuil, K., and Patte,F.: Diminution du taux sérique de rifampicine par le phénobarbital. Presse Méd. 79: 350 (1971).

    Google Scholar 

  • Del Bono, M.; DiFilippo, A., and Lorenzoni, E.: Comportamento dell’allergia tubercolinica in corso di trattamento con rifampicina. Archivio di tisiologia e delle malattie dell’apparato respiratorio 22: 477 (1967).

    PubMed  Google Scholar 

  • Del Bono, M. and Sisti, F.: Su di un caso di ipersensibilità alle rifamicine. Archivio di tisiologia e delle malattie dell’apparato respiratorio 22: 507 (1967).

    PubMed  Google Scholar 

  • De Michele, F.; Iodice, F., and Lappa, B.: Prime osservazioni sull’attività terapeutica della rifampicina associata alla streptomicina o alla isomazide. Archivio di tisiologia e delle malattie dell’apparato respiratorio 23: 377 (1968).

    PubMed  Google Scholar 

  • Dettli, L. and Spring, P.: Factors influencing drug elimination in man II. Farmaco 23: 105 (1968).

    Google Scholar 

  • Devine, L.F.; Johnson, D.P.; Hagerman, C.R.; Pierce, W.E.; Rhode, S.L., and Peckinpaugh, R.O.: Rifampicin levels in serum and saliva and effect on the meningococcal carrier state. Journal of the American Medical Association 214: 1055 (1970).

    PubMed  CAS  Google Scholar 

  • Dickinson, J.M. and Mitchison, D.A.: In vitro studies on the choice of drugs for intermittent chemotherapy of tuberculosis. Tubercle (Lond.) 47: 370 (1966).

    Google Scholar 

  • Dickinson, J.M. and Mitchison, D.A.: Suitability of rifampicin for intermittent administration in the treatment of tuberculosis. Tubercle (Lond.) 51: 82 (1970).

    CAS  Google Scholar 

  • Dickinson, J.M.; Ellard, G.A., and Mitchison, D.A.: Suitability of isoniazid and ethambutol for intermittent administration in the treatment of tuberculosis. Tubercle (Lond.) 49: 351 (1968).

    CAS  Google Scholar 

  • Diggelmann, Heidi and Weissmann, C.: Rifampicin inhibits focus formation in chick fibroblasts infected with Rous Sarcoma virus. Nature 224: 1277 (1969).

    PubMed  CAS  Google Scholar 

  • Engbaek, H.C. and Vergmann, B.: Rifampicin in the treatment of drug-resistant tuberculosis. Scandinavian Journal of Respiratory Disease 51: 11 (1970).

    CAS  Google Scholar 

  • Ezekiel, D.H. and Hutchins, J.E: Another mutant of E. coli containing an altered RNA polymerase. Nature 220: 276 (1968).

    PubMed  CAS  Google Scholar 

  • Faine, S. and Knight, D.C.: Rapid microbiological assay of antibiotic in blood and other body fluids. Lancet 2: 375 (1968).

    PubMed  CAS  Google Scholar 

  • Fortuni, M.; Cicogna, A.; Princiotta, M.; Vagni, E., and Grossholz, G.: Primi risultati del trattamento della tubercolosi polmonare con rifampicina. Rivista della tubercolosi e delle malattie dell’apparato respiratorio 16: 290 (1968).

    Google Scholar 

  • Furesz, S.: Chemical and biological properties of rifampicin; in Freerksen, Orlowski and Thumim Antibiotica et Chemotherapia, vol. 16, p. 316 (Karger, Basel 1970).

  • Furesz, S.; Scotti, R.; Pallanza, R., and Mapelli, E.: Rifampicin: a new rifamycin absorption, distribution and elimination in man. Arzneimittel-Forschung 17: 534 (1967).

    PubMed  CAS  Google Scholar 

  • Grumbach, F.: Experimental in vivo studies of new antituberculosis drugs: capreomycin, ethambutol, rifampicin. Tubercle (suppl.) 50: 12 (1969).

    Google Scholar 

  • Grumbach, F.; Canetti, G., and Le Lirzin, M.: Rifampicin in daily and intermittent treatment of experimental murine tuberculosis with emphasis on late results. Tubercle (Lond.) 50: 280 (1969).

    CAS  Google Scholar 

  • Grumbach, F. and Rist, N.: The experimental tuberculostatic effect of rifampicin, a derivative of rifamycin SV. Revue de Tuberculose et de Pneumologie 31: 749 (1967).

    PubMed  CAS  Google Scholar 

  • Gyselen, A. and Simon-Pouthier, F.: Clinical results in first treatment and retreatment of advanced pulmonary tuberculosis with rifampicin. Tubercle (Lond.) 50: 328 (1969).

    Google Scholar 

  • Gyselen, A.; Verbist, L.; Cosemans, J.; Lacquet, L.M., and Vandenperch, E.: Rifampicin and ethambutol in the retreatment of advanced pulmonary tuberculosis. American Review of Respiratory Diseases 98: 933 (1968).

    CAS  Google Scholar 

  • Hartmann, G.; Honikel, K.O.; Knusel, F., and Neusch, J.: The specific inhibition of the DNA-directed RNA synthesis by rifampicin. Biochemica et Biophysica Acta 145: 843 (1967).

    CAS  Google Scholar 

  • Havel, A.; Adámek, L., and Šimonová, S.: Rifampicin in experimental investigations on mice; in Freerksen, Orlowski and Thumim Antibiotica et Chemotherapia, vol. 16, p. 406 (Karger, Basel 1970).

  • Heller, E.; Argaman, M.; Levy, H., and Goldblum, N.: Selective inhibition of vaccinia virus by the antibiotic rifampicin. Nature 222: 273 (1969).

    PubMed  CAS  Google Scholar 

  • Hellström, P-E. and Repo, U.K.: Capreomycin, ethambutol and rifampicin in apparently incurable pulmonary tuberculosis. Scandinavian Journal of Respiratory Diseases (suppl.) 69: 69 (1969)

    Google Scholar 

  • Hobby, Gladys L. and Lenert, Tulita F.: The antimycobacterial activity of rifampicin. American Review of Respiratory Diseases 97: 713 (1968).

    CAS  Google Scholar 

  • Hobby, Gladys L. and Lenert, Tulita F.: The action of rifampicin alone and in combination with other antituberculosis drugs. American Review of Respiratory Diseases 102: 462 (1970).

    CAS  Google Scholar 

  • Hollins, P.J. and Simmons, A.V: Jaundice associated with rifampicin. Tubercle (Lond.) 51: 328 (1970).

    CAS  Google Scholar 

  • Hugues, F.-C.; Marche, C., and Marche, J.: Effets hepatobiliaires de l’association rifampicine-isoniazide. Thérapie 24: 899 (1969).

    PubMed  CAS  Google Scholar 

  • Hugues, F.-C.; Marche, C., and Marche, J.: Effets hépatobiliaires de l’association rifampicine-prothionamide. Thérapie 25: 131 (1970).

    PubMed  CAS  Google Scholar 

  • Jouhar, A.J.: The rifamycin antibiotics — in retrospect and prospect. Journal of Therapeutics and Clinical Research 2: 17(1968).

    Google Scholar 

  • Kaspar, M.C. and Regli, J.: Rifampicin-Monotherapie bei chronischer, bazillärer Lungentuberkulose. Chemotherapia 4: 43 (1967).

    Google Scholar 

  • Konig, K.: Rifampicin in the treatment of urogenital tuberculosis. Cited in abstracts of papers presented at the 6th International Congress of Chemotherapy, August 10–15, 1969 and Post-Congress Symposium I, August 16–17, 1969, Tokyo, Japan, p. 280 (1969).

  • Konopka, E.A.; Zoganas, H.C.; Lewis, L., and Gelzer, J.: Chemotherapeutic activity of rifampicin against Gram-negative bacteria with reference to urinary tract infection in rats. Antimicrobial Agents and Chemotherapy 13: 519 (1968).

    Google Scholar 

  • Kradolfer, F.: Analyse der Wirksamkeit von Rifamycin-Derivaten und bekannten Therapeutika erster Ordnung und der murinen Tuberkulose. Chemotherapia 12: 369 (1967).

    Google Scholar 

  • Kunin, C.M.; Brandt, D., and Wood, H.: Bacteriologic studies of rifampicin, a new semisynthetic antibiotic. Journal of Infectious Diseases 119: 132 (1969).

    PubMed  CAS  Google Scholar 

  • Laumen, F.: Monotherapie und Kombinationstherapie mit Rifampicin bei 156 Tuberkuloseerkrankungen. Prax. Pneumol. 24: 158 (1970).Abstract in German Medi-cal Monthly 15: 654 (1970).

    PubMed  CAS  Google Scholar 

  • Leading article: British Medical Journal 2: 588(1969).

  • Lees, A.W.; Asgher, B.; Hashem, M.A., and Sinha, B.N.; Jaundice after rifampicin. British Journal of Diseases of the Chest 64: 90 (1970).

    PubMed  CAS  Google Scholar 

  • Lesobre, R.; Ruffino, J.; Teyssier, L.; Achard, F., and Brefort, G.: Les ictères au cours du traitement par la rifampicine. Revue de Tuberculose et de Pneumologie 33: 393 (1969).

    PubMed  CAS  Google Scholar 

  • Lorian, V. and Finland, M.: In vitro effect of rifampicin on mycobacteria. Applied Microbiology 17: 202 (1969).

    PubMed  CAS  Google Scholar 

  • Lucchesi, M. and Mancini, P.: Antimycobacterial activity of rifampicin; in Freerksen, Orlowski and Thumim Antibiotica et Chemotherapia, vol. 16, p. 431 (Karger, Basel 1970).

  • Lucchesi, M.; Pallotta, G.; Rossi, P., and Sbampato, M.: L’azione terapeutica della rifampicina, derivato 3-(4-metil-1-piperazinil-iminometil)-rifampicina SV, nella tubercolosi polmonare. Annali dell’Istituto “Carlo Forlanini” 27: 199 (1967).

    CAS  Google Scholar 

  • Lucchesi, M. and Rossi, P.: Impiego clinico della rifampicina nella tubercolosi polmonare dell’adulto. Rivista della tubercolosi e delle malattie dell’apparato respiratorio 16: 260 (1968).

    Google Scholar 

  • Maggi, N.F.; Furesz, S.; Pallanza, R., and Pelizza, G.: Rifampicin de-acetylation in the human organism. Arzneimittel-Forschung 19: 643 (1969).

    Google Scholar 

  • Maggi, N.; Pasqualucci, C.R.; Ballotta, R., and Sensi, P.: Rifampicin: a new orally active rifamycin. Chemotherapia 11: 285 (1966).

    CAS  Google Scholar 

  • Manten, A. and Van Wijngaarden, L.J.: Development of drug resistance to rifampicin. Chemotherapy 14: 93 (1969).

    PubMed  CAS  Google Scholar 

  • di Mauro, E.; Synder, L.; Marino, P.; Lamberti, A.; Coppo, A., and Tocchini-Valentini, G.P.: Rifampicin sensitivity of the components of DNA-dependent RNA polymerase. Nature 222: 533 (1969).

    PubMed  Google Scholar 

  • May, P.: Clinical findings with rifampicin in tuberculosis of the urogenital tract; in Freerksen, Orlowski and Thumim Antibiotica et Chemotherapia, vol. 16, p. 480 (Karger, Basel 1970).

  • McCabe, W.R. and Lorian, V.: Comparison of the antibacterial activity of rifampicin and other antibiotics. American Journal of the Medical Sciences 256: 255 (1968).

    PubMed  CAS  Google Scholar 

  • Michot, F.; Bürgi, M., and Büttner, J.: Rimactan (Rifampizin) und Antikoagulantientherapie. Schweizerische medizinische Wochenschrift 100: 583 (1970).

    PubMed  CAS  Google Scholar 

  • Monaco, A.: Il trattamento della tubercolosi polmonare con rifampicina practica sanatoriale. Rivista della tubercolosi e delle malattie dell’apparato respiratorio 16: 273 (1968).

    Google Scholar 

  • Moncalvo, F. and Moreo, G.: Ulteriori ricerche cliniche sull’impiego di una nuova rifamicina orale (rifampicinao rifaldazina) nella terapia della tubercolosi polmonare. Rivista di patologia e clinica della tubercolosi 40: 782 (1967).

    Google Scholar 

  • Moss, B.; Rosenblum, Edith N.; Katz, E., and Grimley, P.M.: Rifampicin: a specific inhibitor of vaccina virus assembly. Nature 224: 1280 (1969).

    PubMed  CAS  Google Scholar 

  • Murdoch, J.McC.; Spiers, C.F.; Wright, N., and Wallace, Edith T.: Rifampicin. Lancet 1: 1094(1969).

    PubMed  CAS  Google Scholar 

  • Nitti, V.: L’attività della rifampicina in vitro sui micobatteri atipici. Archivio di tisiologia e delle malattie dell’apparato respiratorio 22: 498 (1967).

    PubMed  CAS  Google Scholar 

  • Nitti, V.; Catena, E.; Bariffi, F., and Delli Veneri, F.: L’attività terapeutica della rifampicina nella tubercolosi polmonare. Archivio di tisiologia e delle malattie dell’apparato respiratorio 22: 417 (1967a).

    PubMed  CAS  Google Scholar 

  • Nitti, V.; Catena, E.; Ninni, A., and DiFilippo, A.: Indagini sperimentali sull’attività antimicobatterica della rifampicina. Archivio di tisiologia e delle malattie dell’apparato respiratorio 21: 867 (1966).

    PubMed  CAS  Google Scholar 

  • Nitti, V.; Catena, E.; Ninni, A., and DiFilippo, A.: Activity of rifampicin in experimental tuberculosis of the guinea pig. Chemotherapia 12: 369 (1967b).

    CAS  Google Scholar 

  • Nitti, V. and Ninni, A.: In vivo bactericidal activity of rifampicin in combination with other antimycobacterial agents. Chemotherapy 14: 356 (1969).

    PubMed  CAS  Google Scholar 

  • Pallanza, R.; Arioli, V.; Furesz, S., and Bolzoni, G.: Rifampicin: a new rifamycin. Arzneimittel-Forschung 17: 529 (1967).

    PubMed  CAS  Google Scholar 

  • Peard, Mary C.; Fleck, D.G.; Garrod, L.P., and Waterworth, Pamela M.: Combined rifampicin and erythromycin for bacterial endocarditis. British Medical Journal 4: 410 (1970).

    PubMed  CAS  Google Scholar 

  • Pechère, J.C. and Tancrède, C.: Changes in the levels of rifampicin in the serum and urine during the course of treatment. Pathologie et biologie 17: 155 (1969). Abstract in Abstracts of World Medicine 43: 564 (1969).

    PubMed  Google Scholar 

  • Pines, A.; Raafat, H., and Bundi, R.: The rifamycins with other drugs in the treatment of pulmonary tuberculosis: a report of 9 cases. Tubercle (Lond.) 48: 281 (1967).

    CAS  Google Scholar 

  • Pines, A.; Raafat, H., and Siddiqui, G.M.: Rifampicin and ethambutol in the treatment of drug resistant and far advanced pulmonary tuberculosis. Journal of the Irish Medical Association 63: 82 (1970).

    PubMed  CAS  Google Scholar 

  • Porpáczy, P.: Rifampicin in the treatment of chronic urinary tract infections with Gram-negative bacteria. Proceedings of the 6th International Congress of Chemotherapy, Tokyo. A10d-6: 230, abstract (1969).

    Google Scholar 

  • Radenbach, K.L.: Results of clinical studies with capreomycin, ethambutol and rifampicin in the Heckeshorn Hospital, Berlin. Scandinavian Journal of Respiratory Diseases (suppl.) 69: 43 (1969).

    CAS  Google Scholar 

  • Rees, R.J.W.; Pearson, J.M.H., and Walters, M.F.R.: Experimental and clinical studies of rifampicin in treatment of leprosy. British Medical Journal 1: 89 (1970).

    PubMed  CAS  Google Scholar 

  • Rocha, H.P. and Sanchez, A.S.: Use of a new rifamycin SV derivative in chronic urinary infections. Arzneimittel-Forschung 20: 101 (1970).

    Google Scholar 

  • Sanchez Sañudo, L.; Ricart, J.M., and Perli, E.: Tratamiento de la gonorrea con rifampicina. D’ia médico (Argentina) 41: 952 (1969).

    Google Scholar 

  • Spring, P. and Dettli, L.: Über die Pharmakokinetik des Rifampizins bei normaler und bei pathologisch veränderter Elimination. Chemotherapia 5: 95 (1967).

    Google Scholar 

  • Stottmeier, K.D.; Kubica, G.P., and Woodley, C.L.: Antimycobacterial activity of rifampicin. Applied Microbiology 17: 862 (1969).

    Google Scholar 

  • Subak-Sharpe, J.; Timbury, M.C., and Williams, J.F.: Rifampicin inhibits the growth of some mammalian viruses. Nature 222: 341 (1969).

    PubMed  CAS  Google Scholar 

  • Tafton, H.M. and Lind, H.E.: The treatment of urinary tract infections with a new antibiotic. Clinical Medicine 77: 30 (1970).

    Google Scholar 

  • Tan, K.B. and McAuslan, B.R.: Effect of rifampicin on poxvirus protein synthesis. Journal of Virology 6: 326 (1970).

    PubMed  CAS  Google Scholar 

  • Tocchini-Valentini, G.P.; Marino, P., and Colvill, A.J.: Mutant of E. coli containing an altered RNA polymerase. Nature 220: 275 (1968).

    PubMed  CAS  Google Scholar 

  • Vall-Spinosa, A.; Lester, W.; Moulding, R.; Davidson, P.T., and McClatchy, J.K.: Rifampin in the treatment of drug-resistant Mycobacterium tuberculosis infections. New England Journal of Medicine 283: 616 (1970).

    PubMed  CAS  Google Scholar 

  • Verbist, L.: Tuberculostatic activity of rifampicine in vitro and in vivo presented at 5th International Congress of Chemotherapy, Vienna, 1967, p. 521 (1967).

  • Verbist, L. and Gyselen, A.: Antituberculous activity of rifampicin in vitro and in vivo and the concentrations obtained in human blood. American Review of Respiratory Diseases 98: 923 (1968).

    CAS  Google Scholar 

  • Virchow, Chr. and Flemming, J.: Rifampizin als Tuberkulostatikum. Deutsche medizinische Wochenschrift 92: 2217 (1967).

    PubMed  CAS  Google Scholar 

  • Viswanathan, R.; Rao, P.U.; Dusaj, M.; Sarkar, D.K., and Bhakta, U.S.: Control clinical trial with rimactane in fresh, untreated cases of pulmonary tuberculosis. Indian Journal of Medical Research 58: 519 (1970).

    PubMed  CAS  Google Scholar 

  • Wardell, W.M. and McQueen, E.G.: Urinary excretion of rifampicin and its metabolites as an index of rifampicin blood levels. New Zealand Medical Journal 72: 393 (1970).

    PubMed  CAS  Google Scholar 

  • Wardell, W.M.; Yule, A.G.; Ballard, D.L., and Forsyth, A.: Modification of the pH method of antibiotic bioassay for penicillins, cephalosporins and other antibiotics. Proceedings of the University of Otago Medical School 48: 24 (1970).

    Google Scholar 

  • Wäre, M.: Rifampicin in the treatment of resistant pulmonary tuberculosis. Scandinavian Journal of Respiratory Diseases (suppl.) 72: 113 (1970).

    Google Scholar 

  • Wäre, M.; Heinivaara, O.; Elo, R., and Tola, E.: Clinical experience of the treatment of drug-resistant pulmonary tuberculosis with rifampicin combined with ethambutol and capreomycin. Scandinavian Journal of Respiratory Diseases (suppl.) 69: 59 (1969).

    Google Scholar 

  • Wehrli, W. and Staehelin, M.: Interaction of rifamycin with RNA polymerase. Proceedings of the 6th International Congress of Chemotherapy, Tokyo. B1-5: 392, abstract (1969).

    Google Scholar 

  • Zakay-Rones, Z. and Becker, Y.: Antipoxvirus activity of rifampicin associated with hydrazone side chain. Nature 226: 1162 (1970).

    PubMed  CAS  Google Scholar 

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Rifampicin: A Review. Drugs 1, 354–398 (1971). https://doi.org/10.2165/00003495-197101050-00002

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