Conclusions
The intrathecal route of administration should no longer be thought of as an exotic way of treating diseases of the nervous system. With current implantable technology, access to the lumbar subarachnoid space is clinically acceptable and carries a low risk of infection. Moreover, the pharmacokinetics of drugs delivered intrathecally can be as predictable as with any other route of administration.
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Kroin, J.S. Intrathecal Drug Administration. Clin. Pharmacokinet. 22, 319–326 (1992). https://doi.org/10.2165/00003088-199222050-00001
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DOI: https://doi.org/10.2165/00003088-199222050-00001
Keywords
- Morphine
- Baclofen
- GABAB Receptor
- Intrathecal Morphine
- Intrathecal Baclofen