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Uses and Limitations of Positron Emission Tomography in Clinical Pharmacokinetics/Dynamics (Part I)

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  • Clinical Pharmacokinetic Concepts
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Summary

Positron emission tomography (PET) involves imaging the biodistribution and tissue localisation of small amounts of radiolabelled biomolecules or drugs. In Part I of this article, the applications of pharmacokinetics in PET are discussed in order to derive quantitative measures of physiological function. Part II will examine the use of PET imaging as a tool to study the pharmacokinetics and pharmacodynamics of specific drugs.

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Authors and Affiliations

  1. PET Imaging Center, Department of Radiology, University of Iowa, Iowa City, Iowa, USA

    Laura L. Boles Ponto & James A. Ponto

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  1. Laura L. Boles Ponto
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  2. James A. Ponto
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A complete reference list will appear in Part II of this article in the next issue of the Journal.

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Ponto, L.L.B., Ponto, J.A. Uses and Limitations of Positron Emission Tomography in Clinical Pharmacokinetics/Dynamics (Part I). Clin. Pharmacokinet. 22, 211–222 (1992). https://doi.org/10.2165/00003088-199222030-00003

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  • DOI: https://doi.org/10.2165/00003088-199222030-00003

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