Skip to main content
Log in

Drug Consumption During the Last Decade Among Persons Born in 1902 in Umeå Sweden

A Longitudinal Population Study

  • Original Research Article
  • Published:
Drugs & Aging Aims and scope Submit manuscript

Summary

A population study of drug consumption among people born in 1902 was performed in Umeå, Sweden. The cohort was followed between 79 and 88 years of age. The number of persons in the study varied between 124 and 72. Mean consumption increased from 2.5 to 5.2 drugs per man and from 3.3 to 5.3 per woman. The main correlate of this increase was shown to be the aging individuals’ greater morbidity. Cardiovascular preparations, analgesics, psychoactive substances and drugs used to alleviate gastrointestinal symptoms were the most common. At the age of 88 years, 45 to 55% of the individuals used drugs belonging to each one of these drug groups. Furthermore, during the 9 years of study there was a substantial increase in use of these drug groups except for the cardiovascular agents, of which the consumption was constant. The proportion of subjects on regular drugs increased from 82% at 79 years to 95% at 88 years of age. Benzodiazepines were, at 88 years, used by almost 40% of the population; at the same age, 43% were using laxatives and 37% diuretics. Paracetamol (acetaminophen) was the most common analgesic used. Total consumption of drugs prescribed for hypertension decreased considerably, from 23 to 10%, despite an increase in the use of loop diuretics and vasodilating agents.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Amery A, Birkenhäger W, Brixko P, Bulpitt C, Clement D, et al. Mortality and morbidity results from the European Working Party on high blood pressure in the elderly trial. Lancet 1: 1349–1354, 1985

    Article  PubMed  CAS  Google Scholar 

  • Amery A, Hansson L, Andrén L, Gudbrandsson T, Sivestsson R, et al. Hypertension in the elderly. Acta Medica Scandinavie 210: 221–229, 1981

    Article  CAS  Google Scholar 

  • Bergman U, Wiholm B-E. Patient medication on admission to a medical clinic. European Journal of Clinical Pharmacology 20: 185–191, 1981

    Article  PubMed  CAS  Google Scholar 

  • Boethius G. Recording of drug prescriptions in the county of Jämtland, Sweden. Acta Medica Scandinavica 202: 241–251, 1977

    Article  PubMed  CAS  Google Scholar 

  • Burns E, Austin CA, Bax NDS. Elderly patients’ understanding of their drug therapy: the effect of cognitive function. Age and Ageing 19: 236–240, 1990

    Article  PubMed  CAS  Google Scholar 

  • Chen LH, Liu S, Cook Newell ME, Barnes K. Survey of drug use by the elderly and possible impact of drugs on nutritional status. Drug-Nutrient Interactions 3: 73–86, 1985

    PubMed  CAS  Google Scholar 

  • Fry J. Natural history of hypertension: a case for selective non-treatment. Lancet 2: 431–433, 1974

    Article  PubMed  CAS  Google Scholar 

  • Gardner P, Cluff LE. The epidemiology of adverse drug reactions. A review and perspective. Johns Hopkins Medical Journal 126: 77–87, 1970

    PubMed  CAS  Google Scholar 

  • Greenblatt DJ, Sellers EM, Shader RI. Drug disposition in old age. New England Journal of Medicine 306: 1081–1088, 1982

    Article  PubMed  CAS  Google Scholar 

  • Guttman D. Patterns of legal drug use by older Americans. Addictive Diseases 3: 337–356, 1978

    Google Scholar 

  • Hale WE, Perkins LL, May FE, Marks RG, Stewart RB. Symptom prevalence in the elderly. An evaluation of age, sex, disease and medication use. Journal of the American Geriatrics Society 34: 333–340, 1986

    PubMed  CAS  Google Scholar 

  • Helling DK, Lemke JH, Semla TP, Wallace RB, Lipson DP, et al. Medication use characteristics in the elderly: the Iowa 65 + rural health study. Journal of the American Geriatrics Society 35: 4–12, 1987

    PubMed  CAS  Google Scholar 

  • Hendriksen C, Lund E, Strømgård E. Intake of drugs among elderly people in a Danish municipality, Rødovre. Acta Medica Scandinavica 214: 67–71, 1983

    Article  PubMed  CAS  Google Scholar 

  • Holme I, Waaler HT. Five-year mortality in the city of Bergen, Norway, according to age, sex and blood pressure. Acta Medica Scandinavica 200: 229–239, 1976

    Article  PubMed  CAS  Google Scholar 

  • Holstein BE, Almind G, Due P, Holst E. Aeldres selvrapporterede helbred og laegemiddelforbrug. Ugeskrift for laeger 152: 386–391, 1990

    PubMed  CAS  Google Scholar 

  • Hulka BS, Kupper LL, Cassel JC, Efird RL. Medication use and misuse: physiciain-patient discrepancies. Journal of Chronic Diseases 28: 7–21, 1975

    Article  PubMed  CAS  Google Scholar 

  • Hurwitz N. Predisposing factors in adverse reactions to drugs. British Medical Journal 1: 536–539, 1969

    Article  PubMed  CAS  Google Scholar 

  • Knapp DA, Knapp DA, Wiser TH, Michocki RJ, Nuessle SJ, et al. Drug prescribing for ambulatory patients 85 years of age and older. Journal of the American Geriatrics Society 32: 138–143, 1984

    PubMed  CAS  Google Scholar 

  • Lamy PP. Over-the-counter medications: The drug interactions we overlook. Journal of the American Geriatrics Society 30: 69–75, 1982

    Google Scholar 

  • Landahl S. Drug treatment in 70–82-year-old persons. Acta Medica Scandinavica 221: 179–184, 1987

    Article  PubMed  CAS  Google Scholar 

  • Law R. Chalmers C. Medicines and elderly people: a general practice survey. British Medical Journal 1: 565–568, 1976

    Article  PubMed  CAS  Google Scholar 

  • May FE, Stewart RB, Hale WE, Marks RG. Prescribed and non-prescribed drug use in an ambulatory elderly population. Southern Medical Journal 75: 522–528, 1982

    Article  PubMed  CAS  Google Scholar 

  • Montamat SC, Cusack BJ, Vestal RE. Management of drug therapy in the elderly. New England Journal of Medicine 321: 303–309, 1989

    Article  PubMed  CAS  Google Scholar 

  • Nolan L, O’Malley K. Prescribing for the elderly. Part I: Sensitivity of the elderly to adverse drug reactions. Journal of the American Geriatrics Society 36: 142–149, 1988

    PubMed  CAS  Google Scholar 

  • Nordic Council on Medicines. Nordic Statistics on Medicines 1981–1983. Guidelines for ATC classification. NLN Publication No. 14, Uppsala, 1986

  • Österlind P-O, Löfgren A-C, Sandman P-O, Steen B, Winblad B. Health, disorders and drug consumption in an elderly population in northern Sweden. Gerontology 32: 52–59, 1986

    Article  PubMed  Google Scholar 

  • Ouslander JG. Drug therapy in the elderly. Annals of Internal Medicine 95: 711–722, 1981

    PubMed  CAS  Google Scholar 

  • Rozzini R, Bianchetti A, Zanetti O, Trabucchi M. Are too many drugs prescribed for the elderly after all? Journal of the American Geriatrics Society 37: 89–90, 1989

    PubMed  CAS  Google Scholar 

  • Schmucker DL. Drug disposition in the elderly: a review of the critical factors. Journal of the American Geriatrics Society 32: 144–149, 1984

    PubMed  CAS  Google Scholar 

  • Shapiro S, Avery KT, Carpenter RD. Drug utilization by a non-institutionalized ambulatory elderly population. Gerodontics 2: 99–103, 1986

    PubMed  CAS  Google Scholar 

  • Skegg DCG, Doll R, Perry J. Use of medicines in general practice. British Medical Journal 1: 1561–1563, 1977

    Article  PubMed  CAS  Google Scholar 

  • Spagnoli A, Ostino G, Borga AD, DÁmbrosio R, Maggiorotti P, et al. Drug compliance and unreported drugs in the elderly. Jounrnal of the American Geriatrics Society 37: 619–624, 1989

    CAS  Google Scholar 

  • Stewart RB. Noncompliance in the elderly: is there a cure? Drugs and Aging 1: 163–167, 1991

    Article  PubMed  CAS  Google Scholar 

  • Stewart RB, Cluff LE. Studies on the epidemiology of adverse drug reactions VI: utilization and interactions of prescription and nonprescription drugs in outpatients. Johns Hopkins Medical Journal 129: 319–331, 1971

    PubMed  CAS  Google Scholar 

  • Stoller EP. Prescribed and over-the-counter medicine use by the ambulatory elderly. Medical Care 26: 1149–1157, 1988

    Article  PubMed  CAS  Google Scholar 

  • Verbrugge LM. Gender and health: an update on hypotheses and evidence. Journal of Health and Social Behavior 26: 156–182, 1985

    Article  PubMed  CAS  Google Scholar 

  • Verbrugge LM, Steiner RP. Prescribing drugs to men and women. Health Psychology 4: 79–98, 1985

    Article  PubMed  CAS  Google Scholar 

  • Vestal RE. Drug use in the elderly: a review of problems and special considerations. Drugs 16: 358–382, 1978

    Article  PubMed  CAS  Google Scholar 

  • Vestal RE. Pharmacology and aging. Journal of the American Geriatrics Society 30: 191–200, 1982

    PubMed  CAS  Google Scholar 

  • Weedle PB, Poston JW, Parish PA. Drug prescribing in residential homes for elderly people in the United Kingdom. DICP: Annals of Pharmacotherapy 24: 533–536, 1990

    PubMed  CAS  Google Scholar 

  • Wilkinson L. SYSTAT: the system for statistics. SYSTAT, Inc., Evanston, Illinois, 1989

    Google Scholar 

  • Williamson J. Prescribing problems in the elderly. Practitioner 220: 749–755, 1978

    PubMed  CAS  Google Scholar 

  • Williamson J, Chopin JM. Adverse reactions to prescribed drugs in the elderly: a multicentre investigation. Age and Aging 9: 73–80, 1980

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Österlind, PO., Bucht, G. Drug Consumption During the Last Decade Among Persons Born in 1902 in Umeå Sweden. Drugs & Aging 1, 477–486 (1991). https://doi.org/10.2165/00002512-199101060-00007

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00002512-199101060-00007

Keywords

Navigation