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Might Pentoxifylline Have a Role as Adjuvant Therapy for Patients with Giant Cell Arteritis?

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References

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    Schmidt J, Warrington KJ. Polymyalgia rheumatica and giant cell arteritis in older patients: diagnosis and pharmacological management. Drugs Aging 2011; 28(8): 651–6

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    Weyand CM, Younge BR, Goronzy JJ. IFN-γ and IL-17: the two faces of T-cell pathology in giant cell arteritis. Curr Opin Rheumatol 2011 Jan; 23(1): 43–9

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    Moller DR, Wysocka M, Greenlee BM, et al. Inhibition of human interleukin-12 production by pentoxifylline. Immunology 1997 Jun; 91(2): 197–203

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    Samardzic T, Jankovic V, Stosic-Grujicic S, et al. Pentoxifylline inhibits the synthesis and IFN-gamma-inducing activity of IL-18. Clin Exp Immunol 2001 May; 124(2): 274–81

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Acknowledgements

No sources of funding were used to assist in the preparation of this letter. The author has no conflicts of interest that are potentially relevant to the content of this letter.

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Correspondence to Dr Francisco José Fernández-Fernández.

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Fernández-Fernández, F.J. Might Pentoxifylline Have a Role as Adjuvant Therapy for Patients with Giant Cell Arteritis?. Drugs Aging 28, 847 (2011). https://doi.org/10.2165/11596480-000000000-00000

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Keywords

  • Corticosteroid
  • Pentoxifylline
  • Giant Cell Arteritis
  • Polymyalgia Rheumatica
  • Immunological Disorder