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Pediatric Drugs

, Volume 14, Issue 2, pp 71–77 | Cite as

Medical Management of Nocturnal Enuresis

  • Aniruddh V. Deshpande
  • Patrina H. Y. CaldwellEmail author
Therapy in Practice

Abstract

Nocturnal enuresis, or bedwetting, is the most common cause of urinary incontinence in children. It is known to have a significant psychosocial impact on the child as well as the family.

Nocturnal enuresis typically presents as failure to become dry at night after successful daytime toilet training. It can be primary or secondary (developing after being successfully dry at night for at least 6 months). Children with nocturnal enuresis may have excessive nocturnal urine production, poor sleep arousal and/or reduced bladder capacity. Alarm therapy is the recommended first-line therapy, with treatment choices being influenced by the presence or absence of the abnormalities mentioned above.

Children with nocturnal enuresis may also have daytime urinary urgency, frequency or incontinence of urine. This group (non-monosymptomatic nocturnal enuresis) requires a different clinical approach, with a focus on treating daytime bladder symptoms, which commonly involves pharmacotherapy with anti-cholinergic medications and urotherapy (including addressing bowel problems).

This review discusses the current management of nocturnal enuresis using the terminologies recommended by the International Children’s Continence Society.

Keywords

Detrusor Overactivity Oxybutynin Desmopressin Tolterodine Nocturnal Enuresis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The authors have no potential conflicts of interest and no funding was received by any of the authors involved in the writing of this manuscript.

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Copyright information

© Adis Data Information BV 2012

Authors and Affiliations

  • Aniruddh V. Deshpande
    • 1
    • 2
    • 3
  • Patrina H. Y. Caldwell
    • 2
    • 4
    Email author
  1. 1.Department of UrologyThe Children’s Hospital at WestmeadWestmeadAustralia
  2. 2.Centre for Kidney ResearchThe Children’s Hospital at WestmeadWestmeadAustralia
  3. 3.School of Public Health, Sydney Medical SchoolUniversity of SydneyAustralia
  4. 4.Discipline of Paediatrics and Child Health, Sydney Medical SchoolUniversity of SydneyAustralia

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