American Journal of Clinical Dermatology

, Volume 12, Issue 3, pp 181–190 | Cite as

Honey and Wound Healing

An Overview
  • David S. Lee
  • Sammy Sinno
  • Amor Khachemoune
Review Article Honey and Wound Healing


Honey has been used to treat wounds throughout the ages. This practice was rooted primarily in tradition and folklore until the late 19th century, when investigators began to characterize its biologic and clinical effects. This overview explores both historic and current insights into honey in its role in wound care. We describe the proposed antimicrobial, immunomodulatory, and physiologic mechanisms of action, and review the clinical evidence of the efficacy of honey in a variety of acute and chronic wound types. We also address additional considerations of safety, quality, and the cost effectiveness of medical-grade honeys. In summary, there is biologic evidence to support the use of honey in modern wound care, and the clinical evidence to date also suggests a benefit. However, further large, well designed, clinical trials are needed to confirm its therapeutic effects.


Pressure Ulcer Chronic Wound Pyoderma Gangrenosum Venous Ulcer Manuka Honey 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Adis Data Information BV 2011

Authors and Affiliations

  1. 1.Stritch School of MedicineLoyola University ChicagoMaywoodUSA
  2. 2.Veterans Affairs Medical CenterBrooklynUSA
  3. 3.Dermatology ServiceVeterans Affairs HospitalBrooklynUSA

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