Clinical Drug Investigation

, Volume 30, Issue 10, pp 707–710 | Cite as

Aripiprazole as an Augmentation Agent in Treatment-Resistant Body Dysmorphic Disorder

  • Özcan Uzun
  • Barbaros Özdemir
Case Report


Body dysmorphic disorder (BDD) is a relatively common and severe disorder for which pharmacotherapy has been only minimally studied. BDD often appears to respond to selective serotonin reuptake inhibitors (SSRIs), but many patients do not respond or respond only partially. Investigation of SSRI augmentation strategies is therefore needed. We report a case of treatment-resistant BDD that was successfully treated with pharmacological augmentation of fluvoxamine with aripiprazole. The patient, a 43-year-old woman, had been taking a stable dose of fluvoxamine (400 mg/day) for 6 months when she was started on aripiprazole (10 mg/day). After 10 weeks of this treatment, her clinical condition improved markedly, as indicated by a significant decrease in the Body Dysmorphic Disorder Examination score. This case presents some preliminary evidence that addition of the atypical antipsychotic agent aripiprazole may be useful in patients with treatment-resistant BDD. However, results from controlled studies are needed to support this finding.


Aripiprazole Fluvoxamine Pimozide Body Dysmorphic Disorder Augmentation Strategy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



No sources of funding were used to assist in the preparation of this report. The authors have no conflicts of interest that are directly relevant to the content of this report.


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© Adis Data Information BV 2010

Authors and Affiliations

  1. 1.Department of PsychiatryGulhane School of MedicineEtlikTurkey

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