, Volume 28, Issue 10, pp 799–811

Using Comparative Effectiveness Research to Inform Policy and Practice in the UK NHS

Past, Present and Future
International Perspectives Comparative Effectiveness Research in the UK NHS


Health systems that have fixed budgets and a coherent organizational structure generally have found it valuable to have a dedicated primary research capacity to answer decision-oriented value-for-money questions of particular importance to the system. The UK NHS is one example of such a system. Here, we review the historical evolution of building comparative effectiveness research (CER) capacity in the NHS, describe the current situation, with a focus on how this research is used to inform decisions, and discuss present and emerging challenges. We draw some possible lessons for the US, which is currently considering using CER to inform healthcare policy and practice decisions.

Copyright information

© Adis Data Information BV 2010

Authors and Affiliations

  1. 1.NICE International, National Institute for Health and Clinical ExcellenceLondonUK
  2. 2.NIHR Evaluation, Trials and Studies and HTA ProgrammeNational Institute for Health ResearchLondonUK
  3. 3.Clinical PharmacologyLiverpool UniversityLiverpoolUK

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