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American Journal of Clinical Dermatology

, Volume 10, Issue 5, pp 331–335 | Cite as

Generalized Sweet Syndrome Lesions Associated with Behçet Disease

A True Association or Simply Co-Morbidity?
  • Serap Köran Karadoğan
  • Emel Bülbül Başkan
  • Gülçin Alkan
  • Hayriye Saricaoğlu
  • Şükran Tunali
Case Report

Abstract

Sweet syndrome or acute febrile neutrophilic dermatosis is a condition characterized by painful erythematous papules, nodules, and plaques, which demonstrate mature neutrophilic infiltration of the upper dermis histopathologically, and is usually associated with systemic symptoms such as fever and neutrophilia. Generalized Sweet syndrome lesions are usually noted in association with malignancies. Sweet syndrome lesions are rarely seen in patients with Behçet disease and, if present, are usually fewer in number.

In this report, we present two female patients who developed generalized Sweet syndrome lesions during follow-up after the diagnosis of Behçet disease. The clinical and histopathologic findings in our patients together with the data in the literature suggest that generalized Sweet syndrome lesions in a patient with clinically inactive Behçet disease should remind the clinician that a strict differential diagnosis needs to be made between Sweet syndrome associated with Behçet disease and the rare cutaneous manifestation of Behçet disease that resembles the lesions of Sweet syndrome.

Keywords

Human Leukocyte Antigen Elevated Erythrocyte Sedimentation Rate Erythema Nodosum Leukocytoclastic Vasculitis Erythematous Papule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

No sources of funding were used to assist in the preparation of this case report. The authors have no conflicts of interest that are directly relevant to the content of this case report.

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Copyright information

© Adis Data Information BV 2009

Authors and Affiliations

  • Serap Köran Karadoğan
    • 1
  • Emel Bülbül Başkan
    • 2
  • Gülçin Alkan
    • 2
  • Hayriye Saricaoğlu
    • 2
  • Şükran Tunali
    • 2
  1. 1.Eşrefpaşa Hospital, Department of DermatologyBalcova/İzmir-TürkiyeTurkey
  2. 2.Uludag University Medical Faculty, Department of DermatologyBursaTurkey

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