Applied Bioinformatics

, Volume 4, Issue 2, pp 147–150 | Cite as


An Integrated Database and Meta-server of Bacterial Protease Systems
  • Mohd Firdaus Raih
  • Hafiza Aida Ahmad
  • Mohd Yunus Sharum
  • Norazah Azizi
  • Rahmah MohamedEmail author
Application Note


Bacterial proteases are an important group of enzymes that have very diverse biochemical and cellular functions. Proteases from prokaryotic sources also have a wide range of uses, either in medicine as pathogenic factors or in industry and therapeutics. ProLysED (Prokaryotic Lysis Enzymes Database), our meta-server integrated database of bacterial proteases, is a useful, albeit very niche, resource. The features include protease classification browsing and searching, organism-specific protease browsing, molecular information and visualisation of protease structures from the Protein Data Bank (PDB) as well as predicted protease structures.

Availability: ProLysED is integrated into the ProLysES (Prokaryotic Lysis Enzymes Site) website at Access to the ProLysED database is free for academic users upon registration.

Contact: M. Firdaus Raih ( or


Protein Data Bank Perl Script Enzyme Commission Enzyme Commission Number Protein Data Bank File 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We acknowledge the National Biotechnology and Bioinformatics Network (NBBnet), Malaysia, which is hosting ProLysED, and funding from the Microbial Genomics for Gene and Natural Product Discovery IRPATOPDOWN grant (09-02-02-002 BTK/TD/03) from the Ministry of Science, Technology and Innovation, Malaysia. We thank Fuad Muhammad and Noraslinda for miscellaneous technical input and feedback.

The authors have provided no information on conflicts of interest directly relevant to the content of this article.


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Copyright information

© Adis Data Information BV 2005

Authors and Affiliations

  • Mohd Firdaus Raih
    • 1
    • 2
  • Hafiza Aida Ahmad
    • 2
  • Mohd Yunus Sharum
    • 2
  • Norazah Azizi
    • 2
  • Rahmah Mohamed
    • 1
    • 2
    Email author
  1. 1.School of Biosciences and Biotechnology, Faculty of Science and TechnologyUniversiti Kebangsaan MalaysiaBangiMalaysia
  2. 2.Malaysia Genome InstituteUniversiti Kebangsaan Malaysia - Malaysia Technology Development Corporation (UKM-MTDC) Smart Technology CentreBangiMalaysia

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