Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Clarithromycin/hydrocodone/valproic acid interactions

First report of an interaction, leading to fatal hydrocodone overdose in a child: case report

    • 13 Accesses

    This is a preview of subscription content, log in to check access.


    1. 1.

      Madadi P, Hildebrandt D, Gong IY, Schwarz UI, Ciszkowski C, Ross CJD, Sistonen J, Carleton BC, Hayden MR, Lauwers AE, Koren G.Fatal hydrocodone overdose in a child: Pharmacogenetics and drug interactions. Pediatrics 126: e986-e989, No. 4, Oct 2010. Available from: URL: - Canada

    Download references

    Rights and permissions

    Reprints and Permissions

    About this article

    Cite this article

    Clarithromycin/hydrocodone/valproic acid interactions. React. Wkly. 1326, 12–13 (2010).

    Download citation


    • Valproic Acid
    • Clarithromycin
    • Hydromorphone
    • Hydrocodone
    • CYP2D6 Activity