Clinical Drug Investigation

, Volume 22, Issue 3, pp 205–207 | Cite as

Stevens-Johnson Syndrome Associated with Codeine in a Child

  • Rada Boskovic
  • Adriana Costei
  • Leora Horn
  • Gideon Koren
Case Report

Notes

Acknowledgements

This report was supported in part by the Institutes for Health Research and the Research Leadership for Better Pharmacotherapy during Pregnancy and Lactation.

References

  1. 1.
    Schopf E, Stuhmar A, Rzany A, et al. Toxic epidermal necrolysis and Stevens-Johnson syndrome. An epidemiologic study from West Germany. Arch Dermatol 1991; 127: 839–42PubMedCrossRefGoogle Scholar
  2. 2.
    Chan HL, Stern RS, Arndt KA, et al. The incidence of erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis. A population-based study with particular reference to reactions caused by drugs among outpatients. Arch Dermatol 1990; 126: 43–7PubMedCrossRefGoogle Scholar
  3. 3.
    Roujea JC, Kelly JP, Naldi L, et al. Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med 1995; 333: 1600–7CrossRefGoogle Scholar
  4. 4.
    Roujeau JC, Stern RS. Severe adverse cutaneous reactions to drugs. N Engl J Med 1994; 331: 1272–85PubMedCrossRefGoogle Scholar
  5. 5.
    Revuz J, Penso D, Roujeau JC, et al. Toxic epidermal necrolysis. Clinical findings and prognosis factors in 87 patients. Arch Dermatol 1987; 123: 1160–5PubMedCrossRefGoogle Scholar
  6. 6.
    Binaghi M, Koso M, Saiag P, et al. Ocular involvement in Lyell’s syndrome. Incidence, evolution, prognosis. Ophtalmologie 1998; 2: 121–2Google Scholar
  7. 7.
    Hunskaar S, Dragsund S. Scarlatiniform rash and urticaria due to codeine. Ann Allergy 1985; 54: 240–1PubMedGoogle Scholar
  8. 8.
    Monnat A. Etude comparative des syndromes de Lyell et de Steven-Johnson: role etioloque des medicaments. Scheweiz Med Wochenschr 1972; 102(52): 1906–11Google Scholar
  9. 9.
    Eckhardt K, Li S, Ammon S, et al. Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation. Pain 1998; 76(1–2): 27–33PubMedCrossRefGoogle Scholar
  10. 10.
    Berther T, Conroy MC, de Weck AL. Urtikarielle Quaddelreaktion der Haut auf Codein, en Mass der Mastzellenreaktivitat. Scheweiz med Wochenschr 1980; 110: 758–63Google Scholar
  11. 11.
    Shanahan EC, Marshall AG, Garrett CPO. Adverse reactions to intravenous codeine phosphate in children. Anaesthesia 1983; 38: 40–3PubMedCrossRefGoogle Scholar
  12. 12.
    Meyler L. Side effects of drugs. Amsterdam: Elsevier Publishing Company, 1952Google Scholar
  13. 13.
    Compendium of Pharmaceuticals and Specialties. Ottawa (ON): The Canadian Pharmacists Association, 2001Google Scholar
  14. 14.
    Levy M, Sher NH. Mycoplasma pneumoniae infections and Stevens-Johnson syndrome. Report of eight cases and review of the literature. Clin Pediatr (Phila) 1991; 30(1): 42–9CrossRefGoogle Scholar

Copyright information

© Adis International Limited 2002

Authors and Affiliations

  • Rada Boskovic
    • 1
  • Adriana Costei
    • 1
  • Leora Horn
    • 1
  • Gideon Koren
    • 1
  1. 1.Division of Clinical Pharmacology/ToxicologyThe Hospital for Sick ChildrenOntarioCanada

Personalised recommendations