Drugs & Therapy Perspectives

, Volume 17, Issue 5, pp 9–12

Non-nicotine pharmacotherapy may prove useful in smoking cessation

New drugs and disease management


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Covey LS, Sullivan MA, Johnston JA, et al. Advances in non-nicotine therapy for smoking cessation. Drugs 2000; 59(1): 17–31PubMedCrossRefGoogle Scholar
  2. 2.
    Hughes JR, Goldstein MG, Hurt RD, et al. Recent advances in the pharmacotherapy of smoking. JAMA 1999; 281: 72–6PubMedCrossRefGoogle Scholar
  3. 3.
    Fiore MC, Smith SS, Jorenby DE, et al. The effectiveness of nicotine patch for smoking cessation: a meta-analysis. JAMA 1994; 263: 2760–5CrossRefGoogle Scholar
  4. 4.
    Glassman AH, Jackson WK, Walsh BT, et al. Cigarette craving, smoking withdrawal, and clonidine. Science 1984; 226: 864–6PubMedCrossRefGoogle Scholar
  5. 5.
    Gourlay SG, Benowitz NL. Is clonidine an effective smoking cessation therapy? Drugs 1995; 50: 197–207PubMedCrossRefGoogle Scholar
  6. 6.
    Covey LS, Glassman AH. A meta-analysis of double-blind placebo-controlled trials of clonidine for smoking cessation. Br J Addict 1991; 86: 991–8PubMedCrossRefGoogle Scholar
  7. 7.
    Glassman AH, Stetner F, Walsh BT, et al. Heavy smokers, smoking cessation, and clonidine: results of a double-blind, randomized trial. JAMA 1988; 259: 2863–6PubMedCrossRefGoogle Scholar
  8. 8.
    Benowitz NL, Wilson Peng W. Non-nicotine pharmacotherapy for smoking cessation: mechanisms and prospects. CNS Drugs 2000; 13(4): 265–85CrossRefGoogle Scholar
  9. 9.
    AHFS Drug Information 2000. Bethesda MD: American Society of Health System Pharmacists, Inc., 2000Google Scholar
  10. 10.
    British National Formulary No. 39. London: The Pharmaceutical Press, 2000 MarGoogle Scholar
  11. 11.
    Ferry LH, Robbins AS, Scariati PD, et al. Enhancement of smoking cessation using the antidepressant, bupropion hydrochloride [abstract]. Circulation 1992; 86: I–671Google Scholar
  12. 12.
    Ferry LH, Burchette RJ. Efficacy of bupropion for smoking cessation in non-depressed smokers [abstract]. J Addict Dis 1994; 13: 249Google Scholar
  13. 13.
    Hurt RD, Sachs DL, G’Lover ED, et al. A comparison of sustained-release bupropion and placebo for smoking cessation. N Eng J Med 1997; 337: 1195–202CrossRefGoogle Scholar
  14. 14.
    Hall SM, Reus VI, Munoz F, et al. Nortriptyline and cognitive behavioural therapy for the treatment of cigarette smoking. Arch Gen Psychiatry 1998; 55: 683–90PubMedCrossRefGoogle Scholar
  15. 15.
    Prochazka AV, Weaver MJ, Keller RT, et al. A randomised trial of nortriptyline for smoking cessation. Arch Intern Med 1998; 158: 2035–9PubMedCrossRefGoogle Scholar
  16. 16.
    Fowler JS, Volkow ND, Wang GJ, et al. Inhibition of monoamine oxidase B in the brain of smokers. Nature 1996; 379: 733–6PubMedCrossRefGoogle Scholar
  17. 17.
    Berlin I, Spreux-Varoquaux O, Said S, et al. Effects of past history of major depression on smoking characteristics, monoamine oxidase-A and -B activities and withdrawal symptoms in dependent smokers. Drug Alcohol Depend 1997; 45: 31–7PubMedCrossRefGoogle Scholar
  18. 18.
    Berlin I, Said S, Spreux-Varoquaux O, et al. A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers. Clin Trial Ther 1995; 58: 444–52Google Scholar
  19. 19.
    Houtsmuller EJ, Clemmey PA, Sigler LA, et al. Effects of naltrexone on smoking and abstinence: problems of drug dependence 1996 [abstract]. Problems of drugs dependence. Proceedings of the 58th Annual Scientific Meeting of the College on Problems of Drug Dependence Inc. NIDA Res Monogr 1997; 174: 68Google Scholar
  20. 20.
    Covey LS, Glassman AH, Stetner F. Naltrexone’s effects on short-term and long-term smoking cessation. Addictive Dis 1999; 18: 31–40CrossRefGoogle Scholar
  21. 21.
    Jorenby DE, Leischow SJ, Nides MA, et al. A controlled trial of sustained-release bupropion, nicotine patch or both for smoking cessation. N Eng J Med 1999; 340(9): 685–91CrossRefGoogle Scholar
  22. 22.
    Rose JE, Behm FM, Westman EC, et al. Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone. Clin Trials Ther 1994; 56: 86–9Google Scholar

Copyright information

© Adis International Limited 2001

Personalised recommendations