Sports Medicine

, Volume 33, Issue 3, pp 177–186 | Cite as

Use of Nonsteroidal Anti-Inflammatory Drugs Following Exercise-Induced Muscle Injury

  • Angela Baldwin LanierEmail author
Leading Article


The objective of this article is to examine the use of NSAIDs for attenuating exercise-induced muscle injuries (EIMI), with an emphasis on their safety and usefulness for improving muscle function and reducing soreness. NSAIDs are some of the most widely consumed medications in the world, and NSAID use as therapy for EIMI has increased dramatically over the last 20 years. However, there is a lack of agreement concerning NSAID effectiveness for this purpose. The lack of consensus about the efficacy of NSAID use in relation to EIMI has spawned a recent interest in sports medicine research regarding NSAIDs.

The application of a variety of methods used to induce, assess and quantify muscle injury has contributed to the inconsistency among the findings regarding the efficacy of NSAIDs for EIMI. Therefore, future studies should focus on the evaluation of muscle injury and function, with the use of better functional measurement tools and more uniformity in the assessment tools used. However, from review of the current literature, it is concluded that NSAID use for brief periods of time is beneficial for short-term recovery of muscle function and is an important laboratory tool for the study of EIMI.


PGE2 Creatine Kinase Muscle Function Naproxen Sodium Muscle Injury 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The author thanks Steve Lanier, Dr Erica Jackson, Dr Scott Stevenson, Richard Burke and Scott Kimberly for their assistance in the preparation of this manuscript. No sources of funding were used to assist in the preparation of this manuscript. The author has no conflicts of interest that are directly relevant to the content of this manuscript.


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Authors and Affiliations

  1. 1.Department of Health, Physical Education and Sport ScienceKennesaw State UniversityKennesawUSA

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