Sports Medicine

, Volume 29, Issue 6, pp 373–386 | Cite as

The Effect of Endurance Training on Parameters of Aerobic Fitness

  • Andrew M. Jones
  • Helen Carter
Leading Article


Endurance exercise training results in profound adaptations of the cardiorespiratory and neuromuscular systems that enhance the delivery of oxygen from the atmosphere to the mitochondria and enable a tighter regulation of muscle metabolism. These adaptations effect an improvement in endurance performance that is manifest as a rightward shift in the ‘velocity-time curve’. This shift enables athletes to exercise for longer at a given absolute exercise intensity, or to exercise at a higher exercise intensity for a given duration. There are 4 key parameters of aerobic fitness that affect the nature of the velocity-time curve that can be measured in the human athlete. These are the maximal oxygen uptake (V̇O2max), exercise economy, the lactate/ventilatory threshold and oxygen uptake kinetics. Other parameters that may help determine endurance performance, and that are related to the other 4 parameters, are the velocity at V̇O2max (V-V̇O2max) and the maximal lactate steady state or critical power. This review considers the effect of endurance training on the key parameters of aerobic (endurance) fitness and attempts to relate these changes to the adaptations seen in the body’s physiological systems with training. The importance of improvements in the aerobic fitness parameters to the enhancement of endurance performance is highlighted, as are the training methods that may be considered optimal for facilitating such improvements.


Exercise Intensity Blood Lactate Endurance Training Aerobic Fitness Submaximal Exercise 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Wenger HA, Bell GJ. The interactions of intensity, frequency and duration of exercise training in altering cardiorespiratory fitness. Sports Med 1986; 3: 346–56PubMedGoogle Scholar
  2. 2.
    Pierce EF, Weltman A, Seip RL, et al. Effects of training specificity on the lactate threshold and V̇O2 peak. Int J Sports Med 1990; 11: 267–72PubMedGoogle Scholar
  3. 3.
    Neufer PD. The effect of detraining and reduced training on the physiological adaptations to aerobic exercise training. Sports Med 1989; 8: 302–21PubMedGoogle Scholar
  4. 4.
    McKenzie DC. Markers of excessive exercise. Can J Appl Physiol 1999; 24: 66–73PubMedGoogle Scholar
  5. 5.
    Davies CTM, Thomason MW. Aerobic performance of female marathon and male ultramarathon athletes. Eur J Appl Physiol 1979; 41: 233–45Google Scholar
  6. 6.
    Leger L, Mercier D, Gauvin L. The relationship between % V̇2max and running performance time. In: Landers DM, editor. Sport and elite performers. Champaign (IL): Human Kinetics, 1986:113–20Google Scholar
  7. 7.
    Monod H, Scherrer J. The work capacity of a synergic muscle group. Ergonomics 1965; 8: 329–38Google Scholar
  8. 8.
    Wilkie DR. Equations describing power input by humans as a function of duration of exercise. In: Ceretelli P, Whipp BJ, editors. Exercise bioenergetics and gas exchange. North-Holland: Elsevier, 1980: 75–81Google Scholar
  9. 9.
    Whipp BJ, Ward SA, Lamarra N, et al. Parameters of ventilatory and gas exchange dynamics during exercise. J Appl Physiol 1982; 52: 1506–13PubMedGoogle Scholar
  10. 10.
    Hill DW. Energy system contributions in middle-distance running events. J Sports Sci 1999; 17: 477–83PubMedGoogle Scholar
  11. 11.
    Saltin B, Astrand PO. Maximal oxygen uptake in athletes. J Appl Physiol 1967; 23: 353–8PubMedGoogle Scholar
  12. 12.
    Costill DL, Thomason H, Roberts E. Fractional utilisation of the aerobic capacity during distance running. Med Sci Sports 1973; 5: 248–52PubMedGoogle Scholar
  13. 13.
    Saltin B, Strange S. Maximal oxygen uptake: ‘old’ and ‘new’ arguments for a cardiovascular limitation. Med Sci Sports Exerc 1992; 24: 30–7PubMedGoogle Scholar
  14. 14.
    Spina RJ, Ogawa T, Martin WH, et al. Exercise training prevents decline in stroke volume during exercise in young healthy subjects. J Appl Physiol 1992; 72: 2458–62PubMedGoogle Scholar
  15. 15.
    Paterson DH, Shephard RJ, Cunningham D, et al. Effects of physical training upon cardiovascular function following myocardial infarction. J Appl Physiol 1979; 47: 482–9PubMedGoogle Scholar
  16. 16.
    Spina RJ. Cardiovascular adaptations to endurance exercise training in older men and women. Exerc Sport Sci Rev 1999; 27: 317–32PubMedGoogle Scholar
  17. 17.
    Shephard RJ. Exercise physiology and performance of sport. Sports Sci Rev 1992; 1: 1–12Google Scholar
  18. 18.
    Green HJ, Jones LL, Painter DC. Effects of short-term training on cardiac function during prolonged exercise. Med Sci Sports Exerc 1990; 22: 488–93PubMedGoogle Scholar
  19. 19.
    Tabata I, Irisama K, Kouzaki M, et al. Metabolic profile of high intensity intermittent exercises. Med Sci Sports Exerc 1997; 29: 390–5PubMedGoogle Scholar
  20. 20.
    Carter H, Jones AM, Doust JH. Effect of six weeks of endurance training on the lactate minimum speed. J Sports Sci 1999; 17: 957–67PubMedGoogle Scholar
  21. 21.
    Gibbons E, Jessup G, Wells T, et al. Effects of various training intensity levels on anaerobic threshold and aerobic capacity in females. J Sports Med Phys Fitness 1983; 23: 315–8PubMedGoogle Scholar
  22. 22.
    Gaesser GA, Poole DC, Gardner BP. Dissociation between V̇O2max and ventilatory threshold responses to endurance training. Eur J Appl Physiol 1984; 53: 242–7Google Scholar
  23. 23.
    Spina RJ, Chi MM, Hopkins MG, et al. Mitochondrial enzymes increase in muscle in response to 7–10 days of cycle exercise. J Appl Physiol 1996; 80: 2250–4PubMedGoogle Scholar
  24. 24.
    Mier CM, Turner MJ, Ehsani AA, et al. Cardiovascular adaptations to 10 days of cycle exercise. J Appl Physiol 1997; 83: 1900–6PubMedGoogle Scholar
  25. 25.
    Weston A, Myburgh K, Lindsay F, et al. Skeletal muscle buffering capacity and endurance performance after high intensity interval training by well-trained cyclists. Eur J Appl Physiol 1997; 75: 7–13Google Scholar
  26. 26.
    Franch J, Madsen K, Djurhuus MS, et al. Improved running economy following intensified training correlates with reduced ventilatory demands. Med Sci Sports Exerc 1998; 30: 1250–6PubMedGoogle Scholar
  27. 27.
    Billat VL, Flechet B, Petit B, et al. Interval training at V̇O2max: effects on aerobic performance and overtraining markers. Med Sci Sports Exerc 1999; 31: 156–63PubMedGoogle Scholar
  28. 28.
    Hickson R, Hagberg J, Ehsani A, et al. Time course of the adaptive responses of aerobic power and heart rate to training. Med Sci Sports Exerc 1981; 13: 17–20PubMedGoogle Scholar
  29. 29.
    Convertino V. Blood volume: its adaptation to endurance training. Med Sci Sports Exerc 1991; 23: 1338–48PubMedGoogle Scholar
  30. 30.
    Green HJ, Sutton JR, Coates G, et al. Response of red cell and plasma volume to prolonged training in humans. J Appl Physiol 1991; 70: 1810–5PubMedGoogle Scholar
  31. 31.
    Rusko H. Development of aerobic power in relation to age and training in cross-country skiers. Med Sci Sports Exerc 1992; 24: 1040–7PubMedGoogle Scholar
  32. 32.
    Martin D, Vroon D, May D, et al. Physiological changes in elite male distance runners training for Olympic competition. Physician Sports Med 1986; 14: 152–68Google Scholar
  33. 33.
    Jones AM. A 5-year physiological case study of an Olympic runner. Br J Sports Med 1998; 32: 39–43PubMedGoogle Scholar
  34. 34.
    Conley D, Krahenbuhl G. Running economy and distance running performance of highly trained athletes. Med Sci Sports 1980; 12: 357–60Google Scholar
  35. 35.
    Coyle EF, Feltners ME, Kautz SA, et al. Physiological and biomechanical factors associated with elite endurance cycling performance. Med Sci Sports Exerc 1991; 23: 93–107PubMedGoogle Scholar
  36. 36.
    Morgan D, Craib M. Physiological aspects of running economy. Med Sci Sports Exerc 1992; 24: 456–61PubMedGoogle Scholar
  37. 37.
    Horowitz JF, Sidossis LS, Coyle EF. High efficiency of type I muscle fibers improves performance. Int J Sports Med 1994; 15: 152–7PubMedGoogle Scholar
  38. 38.
    Londeree BR. The use of laboratory test results with long distance runners. Sports Med 1986; 3: 201–13PubMedGoogle Scholar
  39. 39.
    Morgan DW, Bransford DR, Costill DL, et al. Variation in the aerobic demand of running among trained and untrained subjects. Med Sci Sports Exerc 1995; 27: 404–9PubMedGoogle Scholar
  40. 40.
    Pate RR, Macera CA, Bailey SP, et al. Physiological, anthropometric, and training correlates of running economy. Med Sci Sports Exerc 1995; 24: 1128–33Google Scholar
  41. 41.
    Morgan DW, Daniels JT. Relationship between V̇O2max and the aerobic demand of running in elite distance runners. Int J Sports Med 1994; 15: 426–9PubMedGoogle Scholar
  42. 42.
    Conley D, Krahenbuhl G, Burkett L, et al. Following Steve Scott: physiological changes accompanying training. Physician Sports Med 1984; 12: 103–6Google Scholar
  43. 43.
    Wilcox A, Bulbulian R. Changes in running economy relative to V̇O2max during a cross-country season. J Sports Med Phys Fitness 1984; 24: 321–6PubMedGoogle Scholar
  44. 44.
    Overend TJ, Paterson DH, Cunningham DA. The effect of interval and continuous training on the aerobic parameters. Can J Appl Sport Sci 1992; 17: 129–34Google Scholar
  45. 45.
    Lake M, Cavanagh P. Six weeks of training does not change running mechanics or improve running economy. Med Sci Sports Exerc 1996; 28: 860–9PubMedGoogle Scholar
  46. 46.
    Patton J, Vogel J. Cross-sectional and longitudinal evaluations of an endurance training program. Med Sci Sports 1977; 9: 100–3PubMedGoogle Scholar
  47. 47.
    Svedenhag J, Sjodin B. Physiological characteristics of elite male runners in and off-season. Can J Appl Sport Sci 1985; 10: 127–33PubMedGoogle Scholar
  48. 48.
    Jones AM, Carter H, Doust JH. Effect of six weeks of endurance training on parameters of aerobic fitness [abstract]. Med Sci Sports Exerc 1999; 31: S1379Google Scholar
  49. 49.
    Bailey SP, Pate RR. Feasibility of improving running economy. Sports Med 1991; 12: 228–36PubMedGoogle Scholar
  50. 50.
    Coyle EF, Sidossis LS, Horowitz JF, et al. Cycling efficiency is related to the percentage of type I muscle fibers. Med Sci Sports Exerc 1992; 24: 782–8PubMedGoogle Scholar
  51. 51.
    Williams K, Cavanagh P. Relationship between distance running mechanics, running economy, and performance. J Appl Physiol 1987; 63: 1236–45PubMedGoogle Scholar
  52. 52.
    Cavanagh PR, Kram R. Mechanical and muscular factors affecting the efficiency of human movement. Med Sci Sports Exerc 1985; 17: 326–31PubMedGoogle Scholar
  53. 53.
    Godges JJ, MacRae H, Longdon C, et al. The effects of two stretching procedures on hip range of motion and gait economy. J Orthop Sports Phys Ther 1989; 7: 350–7Google Scholar
  54. 54.
    Jones AM, Pringle JSM, Martin J. Running economy is negatively related to lower limb flexibility in international standard male distance runners [abstract]. J Sports Sci. In pressGoogle Scholar
  55. 55.
    Gleim GW, Stachenfeld NS, Nicholas JA. The influence of flexibility on the economy of walking and jogging. J Orthop Res 1990; 8: 814–23PubMedGoogle Scholar
  56. 56.
    Craib MW, Mitchell VA, Fields KB, et al. The association between flexibility and running economy in sub-elite male distance runners. Med Sci Sports Exerc 1996; 28: 737–43PubMedGoogle Scholar
  57. 57.
    Heise GD, Martin PE. ‘Leg spring’ characteristics and the aerobic demand of running. Med Sci Sports Exerc 1998; 30: 750–4PubMedGoogle Scholar
  58. 58.
    Hickson RC, Dvorak BA, Gorostiaga EM, et al. Potential for strength and endurance training to amplify endurance performance. J Appl Physiol 1988; 65: 2285–90PubMedGoogle Scholar
  59. 59.
    Marcinik EJ, Potts J, Schlabach G, et al. Effects of strength training on lactate threshold and endurance performance. Med Sci Sports Exerc 1991; 23: 739–43PubMedGoogle Scholar
  60. 60.
    Bishop D, Jenkins DG. The influence of resistance training on the critical power function and time to fatigue at critical power. Aust J Sci Med Sport 1996; 4: 101–5Google Scholar
  61. 61.
    Bishop D, Jenkins DG, Mackinnon LT, et al. The effects of strength training on endurance performance and muscle characteristics. Med Sci Sports Exerc 1999; 31 (6): 886–91PubMedGoogle Scholar
  62. 62.
    Paavolainen L, Hakkinen K, Hamalainen I, et al. Explosive-strength training improves 5-km running time by improving running economy and muscle power. J Appl Physiol 1999; 86 (5): 1527–33PubMedGoogle Scholar
  63. 63.
    Sale DG. Neural adaptations to strength training. In: Komi PV, editor. Strength and power in sport. London: Blackwell Scientific Publications, 1992: 249–65Google Scholar
  64. 64.
    Hoff J, Helgerud J, Wisloff U. Maximal strength training improves work economy in trained female cross-country skiers. Med Sci Sports Exerc 1999; 31 (6): 870–7PubMedGoogle Scholar
  65. 65.
    Daniels J, Daniels N. Running economy of elite male and elite female runners. Med Sci Sports Exerc 1992; 24: 483–9PubMedGoogle Scholar
  66. 66.
    Morgan DW, Baldini FD, Martin PE, et al. Ten kilometer performance and predicted velocity at V̇O2max among well-trained male runners. Med Sci Sports Exerc 1989; 21: 78–83PubMedGoogle Scholar
  67. 67.
    Babineau C, Leger L. Physiological response of 5/1 intermittent aerobic exercise and its relationship to 5-km running performance. Int J Sports Med 1996; 18: 13–9Google Scholar
  68. 68.
    Hill DW, Rowell AL. Running velocity at V̇O2max. Med Sci Sports Exerc 1996; 28: 114–9PubMedGoogle Scholar
  69. 69.
    Jones AM, Doust JH. The validity of the lactate minimum test for determination of the maximal lactate steady state. Med Sci Sports Exerc 1998; 30: 1304–13PubMedGoogle Scholar
  70. 70.
    Noakes TD, Myburgh KH, Schall R. Peak treadmill velocity during the V̇O2max test predicts running performance. J Sports Sci 1990; 8: 35–45PubMedGoogle Scholar
  71. 71.
    Hawley JA, Noakes TD. Peak power output predicts maximal oxygen uptake and performance time in trained cyclists. Eur J Appl Physiol 1992; 65: 79–83Google Scholar
  72. 72.
    Berthoin S, Manteca F, Gerbeaux M, et al. Effect of a 12-week training programme on maximal aerobic speed (MAS) and running time to exhaustion at 100 % of MAS for students aged 14 to 17 years. J Sports Med Phys Fitness 1995; 35: 251–6PubMedGoogle Scholar
  73. 73.
    Daniels JT, Scardina N, Hayes J, et al. Elite and subelite female middle- and long-distance runners. In: Landers DM, editor. Sport and elite performers. Champaigne (IL): Human Kinetics, 1986: 57–72Google Scholar
  74. 74.
    Poole DC, Ward SA, Gardner G, et al. Metabolic and respiratory profile of the upper limit for prolonged exercise in man. Ergonomics 1988; 31: 1265–79PubMedGoogle Scholar
  75. 75.
    Sloniger MA, Cureton KJ, Carrasco DI, et al. Effect of the slow-component rise in oxygen uptake on V̇O2max. Med Sci Sports Exerc 1996; 28: 72–8PubMedGoogle Scholar
  76. 76.
    Hill DW, Smith JC. Determination of critical power by pulmonary gas exchange. Can J Appl Physiol 1999; 24: 74–86PubMedGoogle Scholar
  77. 77.
    Pate RR, Branch JD. Training for endurance sport. Med Sci Sports Exerc 1992; 24: S340–3Google Scholar
  78. 78.
    Billat VL, Renoux JC, Pinoteau J, et al. Times to exhaustion at 100 % of velocity at V̇O2max, and modelling of the time-limit/velocity relationship in elite long-distance runners. Eur J Appl Physiol 1994; 69: 271–3Google Scholar
  79. 79.
    Billat VL, Koralsztein JP. Significance of the velocity at V̇O2max and time to exhaustion at this velocity. Sports Med 1996; 22: 90–108PubMedGoogle Scholar
  80. 80.
    Billat VL, Petit B, Koralsztein JP. Time to exhaustion at the velocity associated with V̇O2max as a new parameter to determine a rational basis for interval training in elite distance runners. Sci Motricite 1996; 28: 13–20Google Scholar
  81. 81.
    Hill DW, Rowell AL. Response to exercise at the velocity associated with V̇O2max. Med Sci Sports Exerc 1997; 29: 113–6PubMedGoogle Scholar
  82. 82.
    Billat VL, Blondel N, Berthoin S. Determination of the velocity associated with the longest time to exhaustion at maximal oxygen uptake. Eur J Appl Physiol 1999; 80: 159–61Google Scholar
  83. 83.
    Smith TP, McNaughton LR, Marshall KJ. Effects of 4-wk training using Vmax/Tmax on V̇O2max and performance in athletes. Med Sci Sports Exerc 1999; 31 (6): 892–6PubMedGoogle Scholar
  84. 84.
    Farrell P, Wilmore J, Coyle E, et al. Plasma lactate accumulation and distance running performance. Med Sci Sports Exerc 1979; 11: 338–44Google Scholar
  85. 85.
    Tanaka K, Matsuura Y, Kumagai S, et al. Relationship of anaerobic threshold and onset of blood lactate accumulation with endurance performance. Eur J Appl Physiol 1983; 52: 51–6Google Scholar
  86. 86.
    Fay L, Londeree B, Lafontaine T, et al. Physiological parameters related to distance running performance in female athletes. Med Sci Sports Exerc 1989; 21: 319–24PubMedGoogle Scholar
  87. 87.
    Yoshida T, Udo M, Iwai K, et al. Physiological characteristics related to endurance running performance in female distance runners. J Sports Sci 1993; 11: 57–62PubMedGoogle Scholar
  88. 88.
    Zoladz JA, Sargeant AJ, Emmerich J, et al. Changes in acid-base status of marathon runners during an incremental field test. Eur J Appl Physiol 1993; 67: 71–6Google Scholar
  89. 89.
    Davis J, Frank M, Whipp BJ, et al. Anaerobic threshold alterations caused by endurance training in middle aged men. J Appl Physiol 1979; 46: 1039–46PubMedGoogle Scholar
  90. 90.
    Denis C, Fouquet R, Poty P, et al. Effect of 40 weeks of endurance training on the anaerobic threshold. Int J Sports Med 1982; 3: 208–14PubMedGoogle Scholar
  91. 91.
    Tanaka K, Matsuura Y, Matsuzaka A, et al. A longitudinal assessment of anaerobic threshold and distance running performance. Med Sci Sports Exerc 1984; 16: 278–82PubMedGoogle Scholar
  92. 92.
    Henritze J, Weltman A, Schurrer RL, et al. Effects of training at and above the lactate threshold on the lactate threshold and maximal oxygen uptake. Eur J Appl Physiol 1985; 54: 84–8Google Scholar
  93. 93.
    Weltman A, Seip R, Snead D, et al. Exercise training at and above the lactate threshold in previously untrained women. Int J Sports Med 1992; 13: 257–63PubMedGoogle Scholar
  94. 94.
    Wells CL, Pate RR. Training for performance of prolonged exercise. Perspect Exerc Sci Sports Med 1988; 1: 357–91Google Scholar
  95. 95.
    Yoshida T, Suda Y, Takeuchi N. Endurance training regimen based upon arterial blood lactate: effect on anaerobic threshold. Eur J Appl Physiol 1982; 41: 223–30Google Scholar
  96. 96.
    Denis C, Dormois D, Lacour J. Endurance training, V̇O2max, and OBLA: a longitudinal study of two different age groups. Int J Sports Med 1984; 5: 167–73PubMedGoogle Scholar
  97. 97.
    Hurley B, Hagberg J, Allen W, et al. Effect of training on blood lactate levels during sub-maximal exercise. J Appl Physiol 1984; 56: 1260–4PubMedGoogle Scholar
  98. 98.
    Gaesser GA, Poole DC. Blood lactate during exercise: time course of training adaptation in humans. Int J Sports Med 1988; 9: 284–8PubMedGoogle Scholar
  99. 99.
    Katch V, Weltman A, Sady S, et al. Validity of the relative percent concept for equating training intensity. Eur J Appl Physiol 1978; 39: 219–27Google Scholar
  100. 100.
    Simon J, Young JL, Gutin B, et al. Lactate accumulation relative to the anaerobic and respiratory compensation thresholds. J Appl Physiol 1983; 54 (1): 13–7PubMedGoogle Scholar
  101. 101.
    Sahlin K. Metabolic factors in fatigue. Sports Med 1992; 13 (2): 99–107PubMedGoogle Scholar
  102. 102.
    Boyd AE, Giamber SR, Mager M, et al. Lactate inhibition of lipolysis in exercising man. Metabolism 1974; 23: 531–42PubMedGoogle Scholar
  103. 103.
    Mader A. Evaluation of the endurance performance of marathon runners and theoretical analysis of test results. J Sports Med Phys Fitness 1991; 31: 1–19PubMedGoogle Scholar
  104. 104.
    Weltman A, Snead D, Seip R, et al. Percentages of maximal heart rate, heart rate reserve and V̇O2max for determining endurance training intensity in male runners. Int J Sports Med 1990; 11: 218–22PubMedGoogle Scholar
  105. 105.
    MacDougall JD. The anaerobic threshold: its significance for the endurance athlete. Can J Sports Sci 1977; 2: 137–40Google Scholar
  106. 106.
    Weltman A. The lactate threshold and endurance performance. Adv Sports Med Fitness 1989; 2: 91–116Google Scholar
  107. 107.
    Hirvonen J. Background factors in endurance running. Proceedings of the XVI European Athletics Coaching Association Congress; 1991 Jan 17–21; Vierumaki, 17–21Google Scholar
  108. 108.
    Londeree BR. Effect of training on lactate/ventilatory thresholds: a meta-analysis. Med Sci Sports Exerc 1997; 29: 837–43PubMedGoogle Scholar
  109. 109.
    Sjodin B, Jacobs I, Svedenhag J. Changes in onset of blood lactate accumulation (OBLA) and muscle enzymes after training at OBLA. Eur J Appl Physiol 1982; 49: 45–57Google Scholar
  110. 110.
    Acavedo EO, Goldfarb AH. Increased training intensity effects on plasma lactate, ventilatory threshold, and endurance. Med Sci Sports Exerc 1989; 21: 563–8Google Scholar
  111. 111.
    Keith SP, Jacobs I, McLellan TM. Adaptations to training at the individual anaerobic threshold. Eur J Appl Physiol 1992; 65: 316–23Google Scholar
  112. 112.
    Favier RJ, Constable SH, Chen M, et al. Endurance exercise training reduces lactate production. J Appl Physiol 1986; 61: 885–9PubMedGoogle Scholar
  113. 113.
    MacRae HSH, Dennis SC, Bosch AN, et al. Effects of training on lactate production and removal during progressive exercise in humans. J Appl Physiol 1992; 72: 1649–56PubMedGoogle Scholar
  114. 114.
    Donovan CM, Pagliassotti MJ. Endurance training enhances lactate clearance during hyperlactatemia. Am J Physiol 1989; 257: E782–9Google Scholar
  115. 115.
    Freund H, Lonsdorfer J, Oyono-Enguelle S, et al. Lactate exchange and removal abilities in sickle cell patients and in untrained and trained healthy humans. J Appl Physiol 1992; 73: 2580–7PubMedGoogle Scholar
  116. 116.
    Bonen A, Baker SK, Hatta H. Lactate transport and lactate transporters in skeletal muscle. Can J Appl Physiol 1997; 22: 531–52PubMedGoogle Scholar
  117. 117.
    Costill DL, Daniels J, Evans W. Skeletal muscle enzymes and fiber composition in male and female track athletes. J Appl Physiol 1976; 40: 149–54PubMedGoogle Scholar
  118. 118.
    Ivy JL, Withers RT, Van Handel PJ, et al. Muscle respiratory capacity and fibre type as determinants of the lactate threshold. J Appl Physiol 1980; 48: 523–7PubMedGoogle Scholar
  119. 119.
    Weston AR, Karamizrak O, Smith A, et al. African runners exhibit greater fatigue resistance, lower lactate accumulation, and higher oxidative enzyme activity. J Appl Physiol 1999; 86 (3): 915–23PubMedGoogle Scholar
  120. 120.
    Aunola S, Rusko H. Does anaerobic threshold correlate with maximal lactate steady state? J Sports Sci 1992; 10: 309–23PubMedGoogle Scholar
  121. 121.
    Andersen P, Henriksson J. Training induced changes in the subgroups of human type II skeletal muscle fibres. Acta Physiol Scand 1977; 99: 123–5PubMedGoogle Scholar
  122. 122.
    Simoneau J-A, Lortie G, Boulay MR, et al. Human skeletal muscle fibre alteration with high intensity intermittent training. Eur J Appl Physiol 1985; 54: 250–3Google Scholar
  123. 123.
    Sale DG, MacDougall JD, Jacobs I, et al. Interaction between concurrent strength and endurance training. J Appl Physiol 1990; 68: 260–70PubMedGoogle Scholar
  124. 124.
    Fitts RH, Costill DL, Gardetto PR. Effect of swim exercise training on human muscle fiber function. J Appl Physiol 1989; 66: 465–75PubMedGoogle Scholar
  125. 125.
    Zhou MY, Klitgaard H, Saltin B, et al. Myosin heavy chain isoforms of human muscle after short-term spaceflight. J Appl Physiol 1995; 78: 1740–4PubMedGoogle Scholar
  126. 126.
    Ingjer F. Effects of endurance training on muscle fibre ATPase activity, capillary supply and mitochondrial content in man. J Physiol 1979; 294: 419–32PubMedGoogle Scholar
  127. 127.
    Green FU, Chin ER, Ball-Burnett M, et al. Increases in human skeletal muscle Na+-K+-ATPase concentration with short-term training. Am J Physiol 1993; 264: C1538–41Google Scholar
  128. 128.
    Pilegaard H, Bangsbo J, Richter EA, et al. Lactate transport studied in sarcolemmal giant vesicles from human muscle biopsies: relation to training status. J Appl Physiol 1994; 77: 1858–62PubMedGoogle Scholar
  129. 129.
    McCullagh KJA, Poole RC, Halestrap AP, et al. Role of the lactate transporter (MCT1) in skeletal muscles. Am J Physiol 1996; 271 (34): E143–50Google Scholar
  130. 130.
    Harms SJ, Hickson RC. Skeletal muscle mitochondria and myoglobin, endurance, and intensity of training. J Appl Physiol 1983; 54: 798–802PubMedGoogle Scholar
  131. 131.
    Schantz PG, Sjoberg B, Svedenhag J. Malate-aspartate and alpha-glycerophosphate shuttle enzyme levels in human skeletal muscle: methodological considerations and effect of endurance training. Acta Physiol Scand 1986; 128: 397–407PubMedGoogle Scholar
  132. 132.
    Suter E, Hoppeler H, Claassen H, et al. Ultrastructural modification of human skeletal muscle tissue with 6-month moderate-intensity exercise training. Int J Sports Med 1995; 16: 160–6PubMedGoogle Scholar
  133. 133.
    Gollnick PD, Saltin B. Significance of skeletal muscle oxidative enzyme enhancement with endurance training. Clin Physiol 1982; 2: 1–12PubMedGoogle Scholar
  134. 134.
    Wibom R, Hultman E, Johansson M, et al. Adaptation of mitochondrial ATP production in human skeletal muscle to endurance training and detraining. J Appl Physiol 1992; 73: 2004–10PubMedGoogle Scholar
  135. 135.
    Moritani T, Takaishi T, Matsumaato T. Determination of maximal power output at neuromuscular fatigue threshold. J Appl Physiol 1993; 74: 1729–34PubMedGoogle Scholar
  136. 136.
    Dudley GA, Tullson PC, Terjung RL. Influence of mitochondrial content on the sensitivity of respiratory control. J Biol Chem 1987; 262: 9109–14PubMedGoogle Scholar
  137. 137.
    Graham TE, Saltin B. Estimation of the mitochondrial redox state in human skeletal muscle during exercise. J Appl Physiol 1989; 66: 561–6PubMedGoogle Scholar
  138. 138.
    Kiens B, Essen-Gustavsson B, Christensen NJ, et al. Skeletal muscle substrate utilisation during sub-maximal exercise in man: effect of endurance training. J Physiol 1993; 469: 459–78PubMedGoogle Scholar
  139. 139.
    Green HJ, Smith D, Murphy P, et al. Training-induced alterations in muscle glycogen utilisation in fibre-specific types during prolonged exercise. Can J Physiol Pharmacol 1990; 68: 1372–6PubMedGoogle Scholar
  140. 140.
    Green HJ, Jones S, Ball-Burnett M, et al. Adaptations in muscle metabolism to prolonged voluntary exercise and training. J Appl Physiol 1995; 78: 138–45PubMedGoogle Scholar
  141. 141.
    Coggan AR, Kohrt WM, Spina RJ, et al. Endurance training decreases plasma glucose turnover and oxidation during moderate intensity exercise in men. J Appl Physiol 1990; 68:990–6PubMedGoogle Scholar
  142. 142.
    Mendenhall LA, Swanson SC, Habash DL, et al. Ten days of exercise training reduces glucose production and utilisation during moderate intensity exercise. Am J Physiol 1994; 266: E136–43Google Scholar
  143. 143.
    Hurley BE, Nemeth PM, Martin WH. Muscle triglyceride utilisation during exercise: effect of training. J Appl Physiol 1986; 60: 562–7PubMedGoogle Scholar
  144. 144.
    Martin WH, Dalsky GP, Hurley BE, et al. Effect of endurance training on plasma free fatty acid turnover and oxidation during exercise. Am J Physiol 1993; 265: E708–14Google Scholar
  145. 145.
    Costill DL, Fink WJ, Hargreaves M. Metabolic characteristics of skeletal muscle detraining from competitive swimming. Med Sci Sports Exerc 1985; 17: 339–43PubMedGoogle Scholar
  146. 146.
    Greiwe JS, Hickner RC, Hansen PA, et al. Effects of endurance exercise training on muscle glycogen accumulation in humans. J Appl Physiol 1999; 87 (1): 222–6PubMedGoogle Scholar
  147. 147.
    Costill DL, Gollnick PD, Janssen ED, et al. Glycogen depletion pattern in human muscle fibres during distance running. Acta Physiol Scand 1973; 89: 374–83PubMedGoogle Scholar
  148. 148.
    Green HJ, Jones LL, Houston ME, et al. Muscle energetics during prolonged cycling after exercise hypervolemia. J Appl Physiol 1989; 66: 622–31PubMedGoogle Scholar
  149. 149.
    Duan C, Winder WW. Effect of endurance training on activators of glycolysis in muscle during exercise. J Appl Physiol 1994; 76: 846–52PubMedGoogle Scholar
  150. 150.
    Roston WL, Whipp BJ, Davis JA, et al. Oxygen uptake kinetics and lactate concentration during exercise in humans. Am Rev Respir Dis 1987; 135: 1080–4PubMedGoogle Scholar
  151. 151.
    Beneke R, von Duvillard S. Determination of maximal lactate steady state response in selected sports events. Med Sci Sports Exerc 1996; 28: 241–6PubMedGoogle Scholar
  152. 152.
    Moritani TA, Nagata HA, deVries HA, et al. Critical power as a measure of critical work capacity and anaerobic threshold. Ergonomics 1981; 24: 339–50PubMedGoogle Scholar
  153. 153.
    Hughson RL, Orok CJ, Staudt LE. A high velocity running test to assess endurance running potential. Int J Sports Med 1984; 5: 23–5PubMedGoogle Scholar
  154. 154.
    Billat VL, Renoux JC, Pinoteau J, et al. Times to exhaustion at 90, 100 and 105 % of velocity at V̇O2max (maximal aerobic speed) and critical speed in elite long distance runners. Arch Phys Biochem 1995; 103: 129–35Google Scholar
  155. 155.
    Whipp BJ. The slow component of O2 uptake kinetics during heavy exercise. Med Sci Sports Exerc 1994; 26: 1319–26PubMedGoogle Scholar
  156. 156.
    Barstow TJ, Jones AM, Nguyen PH, et al. Influence of muscle fiber type and pedal frequency on oxygen uptake kinetics of heavy exercise. J Appl Physiol 1996; 81: 1642–50PubMedGoogle Scholar
  157. 157.
    Gaesser GA, Poole DC. The slow component of oxygen uptake kinetics in humans. Exerc Sport Sci Rev 1996; 24: 35–70PubMedGoogle Scholar
  158. 158.
    Hagberg JM, Hickson RC, Ehsani AA, et al. Faster adjustment to and recovery from sub-maximal exercise in the trained state. J Appl Physiol 1980; 48: 218–24PubMedGoogle Scholar
  159. 159.
    Phillips SM, Green HJ, MacDonald MJ, et al. Progressive effect of endurance training on V̇O2 kinetics at the onset of sub-maximal exercise. J Appl Physiol 1995; 79: 1914–20PubMedGoogle Scholar
  160. 160.
    Chilibeck PD, Paterson DH, Petrella RJ, et al. The influence of age and cardiorespiratory fitness on kinetics of oxygen uptake. Can J Appl Physiol 1996; 21: 185–96PubMedGoogle Scholar
  161. 161.
    Hochachka PW, Matheson GO. Regulating ATP turnover rates over broad dynamic work ranges in skeletal muscles. J Appl Physiol 1992; 73: 1697–703PubMedGoogle Scholar
  162. 162.
    Cadefau J, Green HJ, Cusso R, et al. Coupling of muscle phosphorylation potential to glycolysis after short-term training. J Appl Physiol 1994; 76: 2586–93PubMedGoogle Scholar
  163. 163.
    Grassi B, Poole DC, Richardson RS, et al. Muscle O2 kinetics in humans: implications for metabolic control. J Appl Physiol 1996; 80: 988–98PubMedGoogle Scholar
  164. 164.
    Poole DC, Ward SA, Whipp BJ. The effects of training on the metabolic and respiratory profile of high-intensity cycle ergometer exercise. Eur J Appl Physiol 1990; 59: 421–9Google Scholar
  165. 165.
    Jenkins DG, Quigley BM. Endurance training enhances critical power. Med Sci Sports Exerc 1992; 24: 1283–9PubMedGoogle Scholar
  166. 166.
    Jenkins DG, Quigley BM. The influence of high intensity exercise training on the Wlim-Tlim relationship. Med Sci Sports Exerc 1993; 25: 275–82PubMedGoogle Scholar
  167. 167.
    Casaburi R, Storer TW, Ben-Dov I, et al. Effect of endurance training on possible determinants of V̇O2 during heavy exercise. J Appl Physiol 1987; 62: 199–207PubMedGoogle Scholar
  168. 168.
    Womack CJ, Davis SE, Blumer JL, et al. Slow component of O2 uptake during heavy exercise: adaptation to endurance training. J Appl Physiol 1995; 79: 838–45PubMedGoogle Scholar
  169. 169.
    Poole DC, Schaffartzik W, Knight DR, et al. Contribution of exercising legs to the slow component of oxygen uptake in humans. J Appl Physiol 1991; 71: 1245–53PubMedGoogle Scholar
  170. 170.
    Bulbulian R, Wilcox AR, Darabos BL. Anaerobic contribution to distance running performance of trained cross-country athletes. Med Sci Sports Exerc 1986; 18: 107–13PubMedGoogle Scholar
  171. 171.
    Houmard JA, Costill DL, Mitchell JB, et al. The role of anaerobic ability in middle distance running performance. Eur J Appl Physiol 1991; 62: 40–3Google Scholar
  172. 172.
    Fukuba Y, Whipp BJ. A metabolic limit on the ability to make up for lost time in endurance events. J Appl Physiol 1999; 87 (2): 853–61PubMedGoogle Scholar

Copyright information

© Adis International Limited 2000

Authors and Affiliations

  1. 1.Department of Exercise and Sport Science, Crewe and Alsager FacultyThe Manchester Metropolitan UniversityAlsagerEngland
  2. 2.Whitelands CollegeUniversity of Surrey RoehamptonLondonEngland

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