Drugs

, Volume 68, Issue 11, pp 1511–1527

Cigarette Smoking and Diffuse Lung Disease

Review Article

Abstract

Cigarette smoke, a toxic collection of more than 4000 chemicals generated from combustion of tobacco plant leaves, is known to cause several respiratory ailments, including chronic bronchitis, emphysema and lung cancer, and is associated with an increase in respiratory infections. In addition, cigarette smoking is considered a principal aetiological factor responsible for the development of certain diffuse interstitial and bronchiolar lung diseases, namely respiratory bronchiolitis-interstitial lung disease (RB-ILD), desquamative interstitial pneumonia (DIP) and adult pulmonary Langerhans’ cell histiocytosis (PLCH). Although not exclusively seen in cigarette smokers, substantial clinical and epidemiological data support a central role for smoking as the primary causative agent of most RB-ILD, DIP and PLCH. Additional evidence in support of cigarette smoke as a primary aetiological agent in RB-ILD, DIP and PLCH is the observation that smoking cessation may lead to disease improvement, while recurrence of these disorders has been observed to occur in the transplanted lung upon re-exposure to tobacco smoke. Furthermore, histopathological changes of respiratory bronchiolitis, DIP and PLCH (with or without co-existent emphysema) may be found on lung biopsy in the same individual, implicating smoking as a common inciting agent of these diverse lesions. Recent studies also suggest a role for cigarette smoking as a potential co-factor in the development of acute eosinophilic pneumonia, usual interstitial pneumonia and rheumatoid arthritis-associated interstitial lung disease. In the current review, we propose a novel classification that takes into account the complex relationship between cigarette smoking and diffuse lung diseases. Investigation on the role of smoking as a potential causative factor or modifier of these diverse diffuse lung diseases is important, as smoking cessation utilizing state-of-the-art tobacco cessation efforts should be a central part of therapy, while pharmacotherapy with corticosteroids or other immune modifying agents should be reserved for selected patients.

References|

  1. 1.
    Fraig M, Shreesha U, Savici D, et al. Respiratory bronchiolitis: a clinicopathologic study in current smokers, ex-smokers, and never-smokers. Am J Surg Pathol 2002 May; 26(5): 647–53PubMedCrossRefGoogle Scholar
  2. 2.
    Friedman PJ, Liebow AA, Sokoloff J. Eosinophilic granuloma of lung: clinical aspects of primary histiocytosis in the adult. Medicine (Baltimore) 1981 Nov; 60(6): 385–96CrossRefGoogle Scholar
  3. 3.
    Moon J, du Bois RM, Colby TV, et al. Clinical significance of respiratory bronchiolitis on open lung biopsy and its relationship to smoking related interstitial lung disease. Thorax 1999 Nov; 54(11): 1009–14PubMedCrossRefGoogle Scholar
  4. 4.
    Myers JL, Veal Jr CF, Shin MS, et al. Respiratory bronchiolitis causing interstitial lung disease: a clinicopathologic study of six cases. Am Rev Respir Dis 1987 Apr; 135(4): 880–4PubMedGoogle Scholar
  5. 5.
    Ryu JH, Myers JL, Capizzi SA, et al. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. Chest 2005 Jan; 127(1): 178–84PubMedCrossRefGoogle Scholar
  6. 6.
    Vassallo R, Ryu JH, Schroeder DR, et al. Clinical outcomes of pulmonary Langerhans’ cell histiocytosis in adults. N Engl J Med 2002 Feb 14; 346(7): 484–90PubMedCrossRefGoogle Scholar
  7. 7.
    Caminati A, Harari S. Smoking-related interstitial pneumonias and pulmonary Langerhans cell histiocytosis. Proc Am Thorac Soc 2006 Jun; 3(4): 299–306PubMedCrossRefGoogle Scholar
  8. 8.
    Miyake Y, Sasaki S, Yokoyama T, et al. Occupational and environmental factors and idiopathic pulmonary fibrosis in Japan. Ann Occup Hyg 2005 Apr; 49(3): 259–65PubMedCrossRefGoogle Scholar
  9. 9.
    Baumgartner KB, Samet JM, Stidley CA, et al. Cigarette smoking: a risk factor for idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1997; 155(1): 242–8PubMedGoogle Scholar
  10. 10.
    Nakajima M, Matsushima T. Acute eosinophilic pneumonia following cigarette smoking. Intern Med 2000 Oct; 39(10): 759–60PubMedCrossRefGoogle Scholar
  11. 11.
    Watanabe K, Fujimura M, Kasahara K, et al. Acute eosinophilic pneumonia following cigarette smoking: a case report including cigarette-smoking challenge test. Intern Med 2002 Nov; 41(11): 1016–20PubMedCrossRefGoogle Scholar
  12. 12.
    Kitahara Y, Matsumoto K, Taooka Y, et al. Cigarette smokinginduced acute eosinophilic pneumonia showing tolerance in broncho-alveolar lavage findings. Intern Med 2003 Oct; 42(10): 1016–21PubMedCrossRefGoogle Scholar
  13. 13.
    Shorr AF, Scoville SL, Cersovsky SB, et al. Acute eosinophilic pneumonia among US Military personnel deployed in or near Iraq. JAMA 2004; 292(24): 2997–3005PubMedCrossRefGoogle Scholar
  14. 14.
    Girard M, Israel-Assayag E, Cormier Y. Pathogenesis of hypersensitivity pneumonitis. Curr Opin Allergy Clin Immunol 2004 Apr; 4(2): 93–8PubMedCrossRefGoogle Scholar
  15. 15.
    Vassallo R, Jensen EA, Colby TV, et al. The overlap between respiratory bronchiolitis and desquamative interstitial pneumonia in pulmonary Langerhans cell histiocytosis: high-resolution CT, histologic, and functional correlations. Chest 2003 Oct; 124(4): 1199–205PubMedCrossRefGoogle Scholar
  16. 16.
    Travis WD, Borok Z, Roum JH, et al. Pulmonary Langerhans cell granulomatosis (histiocytosis X): a clinicopathologic study of 48 cases. Am J Surg Pathol 1993 Oct; 17(10): 971–86PubMedCrossRefGoogle Scholar
  17. 17.
    Shiota Y, Kawai T, Matsumoto H, et al. Acute eosinophilic pneumonia following cigarette smoking. Intern Med 2000 Oct; 39(10): 830–3PubMedCrossRefGoogle Scholar
  18. 18.
    Al-Saieg N, Moammar O, Kartan R. Flavored cigar smoking induces acute eosinophilic pneumonia. Chest 2007 Apr; 131(4): 1234–7PubMedCrossRefGoogle Scholar
  19. 19.
    Miki K, Miki M, Okano Y, et al. Cigarette smoke-induced acute eosinophilic pneumonia accompanied with neutrophilia in the blood. Intern Med 2002 Nov; 41(11): 993–6PubMedCrossRefGoogle Scholar
  20. 20.
    Donaghy M, Rees AJ. Cigarette smoking and lung haemorrhage in glomerulonephritis caused by autoantibodies to glomerular basement membrane. Lancet 1983 Dec 17; II(8364): 1390–3CrossRefGoogle Scholar
  21. 21.
    Saag KG, Kolluri S, Koehnke RK, et al. Rheumatoid arthritis lung disease: determinants of radiographic and physiologic abnormalities. Arthritis Rheum 1996 Oct; 39(10): 1711–9PubMedCrossRefGoogle Scholar
  22. 22.
    Wolfe F. The effect of smoking on clinical, laboratory, and radiographie status in rheumatoid arthritis. J Rheumatol 2000 Mar; 27(3): 630–7PubMedGoogle Scholar
  23. 23.
    Peros-Golubicic T, Ljubic S. Cigarette smoking and sarcoidosis. Acta Med Croatica 1995; 49(4-5): 187–93PubMedGoogle Scholar
  24. 24.
    Israel-Assayag E, Dakhama A, Lavigne S, et al. Expression of costimulatory molecules on alveolar macrophages in hypersensitivity pneumonitis. Am J Respir Crit Care Med 1999 Jun; 159(6): 1830–4PubMedGoogle Scholar
  25. 25.
    Colby TV, Lombard C. Histiocytosis X in the lung. Human Pathol 1983 Oct; 14(10): 847–56CrossRefGoogle Scholar
  26. 26.
    Yousem SA, Colby TV, Gaensler EA. Respiratory bronchiolitis-associated interstitial lung disease and its relationship to desquamative interstitial pneumonia. Mayo Clin Proc 1989 Nov; 64(11): 1373–80PubMedCrossRefGoogle Scholar
  27. 27.
    Delobbe A, Durieu J, Duhamel A, et al. Determinants of survival in pulmonary Langerhans’ cell granulomatosis (histiocytosis X). Groupe d’Etude en Pathologie Interstitielle de la Societe de Pathologie Thoracique du Nord. Eur Respir J 1996 Oct; 9(10): 2002–6PubMedCrossRefGoogle Scholar
  28. 28.
    Craig PJ, Wells AU, Doffman S, et al. Desquamative interstitial pneumonia, respiratory bronchiolitis and their relationship to smoking. Histopathology 2004 Sep; 45(3): 275–82PubMedCrossRefGoogle Scholar
  29. 29.
    Nakajima M, Manabe T, Niki Y, et al. A case of cigarette smoking-induced acute eosinophilic pneumonia showing tolerance. Chest 2000 Nov; 118(5): 1517–8PubMedCrossRefGoogle Scholar
  30. 30.
    Luukkainen R, Saltyshev M, Pakkasela R, et al. Relationship of rheumatoid factor to lung diffusion capacity in smoking and non-smoking patients with rheumatoid arthritis. Scand Rheumatol 1995; 24(2): 119–20CrossRefGoogle Scholar
  31. 31.
    Valeyre D, Soler P, Clerici C, et al. Smoking and pulmonary sarcoidosis: effect of cigarette smoking on prevalence, clinical manifestations, alveolitis, and evolution of the disease. Thorax 1988 Jul; 43(7): 516–24PubMedCrossRefGoogle Scholar
  32. 32.
    Hance AJ, Basset F, Saumon G, et al. Smoking and interstitial lung disease. The effect of cigarette smoking on the incidence of pulmonary histiocytosis X and sarcoidosis. Ann N Y Acad Sci 1986; 465: 643–56PubMedCrossRefGoogle Scholar
  33. 33.
    Warren CP. Extrinsic allergic alveolitis: a disease commoner in non-smokers. Thorax 1977 Oct; 32(5): 567–9PubMedCrossRefGoogle Scholar
  34. 34.
    Douglas JG, Middleton WG, Gaddie J, et al. Sarcoidosis: a disorder commoner in non-smokers? Thorax 1986 Oct; 41(10): 787–91PubMedCrossRefGoogle Scholar
  35. 35.
    Etienne B, Bertocchi M, Gamondes JP, et al. Relapsing pulmonary Langerhans cell histiocytosis after lung transplantation. Am J Respir Crit Care Med 1998 Jan; 157(1): 288–91PubMedGoogle Scholar
  36. 36.
    Mogulkoc N, Veral A, Bishop PW, et al. Pulmonary Langerhans’ cell histiocytosis: radiologie resolution following smoking cessation. Chest 1999 May; 115(5): 1452–5PubMedCrossRefGoogle Scholar
  37. 37.
    Portnoy J, Veraldi KL, Schwarz MI, et al. Respiratory bronchiolitis-interstitial lung disease: long-term outcome. Chest 2007 Mar; 131(3): 664–71PubMedCrossRefGoogle Scholar
  38. 38.
    Abbott GF, Rosado-de-Christenson ML, Franks TJ, et al. From the archives of the AFIP: pulmonary Langerhans cell histiocytosis. Radiographies 2004 May–Jun; 24(3): 821–41CrossRefGoogle Scholar
  39. 39.
    Dauriat G, Mal H, Thabut G, et al. Lung transplantation for pulmonary Langerhans’ cell histiocytosis: a multicenter analysis. Transplantation 2006 Mar 15; 81(5): 746–50PubMedCrossRefGoogle Scholar
  40. 40.
    Bernstrand C, Cederlund K, Ashtrom L, et al. Smoking preceded pulmonary involvement in adults with Langerhans cell histiocytosis diagnosed in childhood. Acta Paediatr 2000 Nov; 89(11): 1389–92PubMedCrossRefGoogle Scholar
  41. 41.
    Zeid NA, Muller HK. Tobacco smoke induced lung granulomas and tumors: association with pulmonary Langerhans cells. Pathology 1995 Jul; 27(3): 247–54PubMedCrossRefGoogle Scholar
  42. 42.
    Alp H, Daum RS, Abrahams C, et al. Acute eosinophilic pneumonia: a cause of reversible, severe, noninfectious respiratory failure. J Pediatr 1998 Mar; 132 (3 Pt 1): 540–3PubMedCrossRefGoogle Scholar
  43. 43.
    Nakagome K, Kato J, Kubota S, et al. Acute eosinophilic pneumonia induced by cigarette smoking [in Japanese]. Nihon Kokyuki Gakkai Zasshi 2000 Feb; 38(2): 113–6PubMedGoogle Scholar
  44. 44.
    Klareskog L, Stolt P, Lundberg K, et al. A new model for an etiology of rheumatoid arthritis: smoking may trigger HLADR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum 2006 Jan; 54(1): 38–46PubMedCrossRefGoogle Scholar
  45. 45.
    Vassallo R, Tamada K, Lau JS, et al. Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming. J Immunol 2005 Aug 15; 175(4): 2684–91PubMedGoogle Scholar
  46. 46.
    Cormier Y, Belanger J, Durand P. Factors influencing the development of serum precipitins to farmer’s lung antigen in Quebec dairy farmers. Thorax 1985 Feb; 40(2): 138–42PubMedCrossRefGoogle Scholar
  47. 47.
    Hakala M, Paakko P, Huhti E, et al. Open lung biopsy of patients with rheumatoid arthritis. Clin Rheumatol 1990 Dec; 9(4): 452–60PubMedCrossRefGoogle Scholar
  48. 48.
    Churg A, Muller NL, Flint J, et al. Chronic hypersensitivity pneumonitis. Am J Surg Pathol 2006 Feb; 30(2): 201–8PubMedCrossRefGoogle Scholar
  49. 49.
    Ranney L, Melvin C, Lux L, et al. Systematic review: smoking cessation intervention strategies for adults and adults in special populations. Ann Intern Med 2006 Dec 5; 145(11): 845–56PubMedGoogle Scholar
  50. 50.
    Lancaster T, Stead L, Silagy C, et al. Effectiveness of interventions to help people stop smoking: findings from the Cochrane Library. BMJ 2000 Aug 5; 321(7257): 355–8PubMedCrossRefGoogle Scholar
  51. 51.
    Molyneux A. Nicotine replacement therapy. BMJ 2004 Feb 21; 328(7437): 454–6PubMedCrossRefGoogle Scholar
  52. 52.
    Silagy C, Lancaster T, Stead L, et al. Nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev 2004; (3): CD000146Google Scholar
  53. 53.
    Hurt RD, Sachs DP, Glover ED, et al. A comparison of sustained-release bupropion and placebo for smoking cessation. N Engl J Med 1997 Oct 23; 337(17): 1195–202PubMedCrossRefGoogle Scholar
  54. 54.
    Jorenby DE, Hays JT, Rigotti NA, et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006 Jul 5; 296(1): 56–63PubMedCrossRefGoogle Scholar
  55. 55.
    Kuschner WG, D’Alessandro A, Wong H, et al. Dose-dependent cigarette smoking-related inflammatory responses in healthy adults. Eur Respir J 1996 Oct; 9(10): 1989–94PubMedCrossRefGoogle Scholar
  56. 56.
    Casolaro MA, Bernaudin JF, Saltini C, et al. Accumulation of Langerhans’ cells on the epithelial surface of the lower respiratory tract in normal subjects in association with cigarette smoking. Am Rev Respir Dis 1988 Feb; 137(2): 406–11PubMedGoogle Scholar
  57. 57.
    Remy-Jardin M, Remy J, Gosselin B, et al. Lung parenchymal changes secondary to cigarette smoking: pathologic-CT correlations. Radiology 1993 Mar; 186(3): 643–51PubMedGoogle Scholar
  58. 58.
    Tomita K, Caramori G, Lim S, et al. Increased p21(CIPl/ WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers. Am J Respir Crit Care Med 2002 Sep 1; 166(5): 724–31PubMedCrossRefGoogle Scholar
  59. 59.
    Tazi A, Bonay M, Bergeron A, et al. Role of granulocytemacrophage colony stimulating factor (GM-CSF) in the pathogenesis of adult pulmonary histiocytosis X. Thorax 1996 Jun; 51(6): 611–4PubMedCrossRefGoogle Scholar
  60. 60.
    Tazi A, Bouchonnet F, Grandsaigne M, et al. Evidence that granulocyte macrophage-colony-stimulating factor regulates the distribution and differentiated state of dendritic cells/ Langerhans cells in human lung and lung cancers. J Clin Invest 1993 Feb; 91(2): 566–76PubMedCrossRefGoogle Scholar
  61. 61.
    Wang RD, Wright JL, Churg A. Transforming growth factorbetal drives airway remodeling in cigarette smoke-exposed tracheal explants. Am J Respir Cell Mol Biol 2005 Oct; 33(4): 387–93PubMedCrossRefGoogle Scholar
  62. 62.
    D’Hulst AI, Vermaelen KY, Brusselle GG, et al. Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J 2005 Aug; 26(2): 204–13PubMedCrossRefGoogle Scholar
  63. 63.
    Lu LM, Zavitz CC, Chen B, et al. Cigarette smoke impairs NK cell-dependent tumor immune surveillance. J Immunol 2007 Jan 15; 178(2): 936–43PubMedGoogle Scholar
  64. 64.
    Kode A, Yang SR, Rahman I. Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells. Respir Res 2006; 7: 132PubMedCrossRefGoogle Scholar
  65. 65.
    Yang SR, Chida AS, Bauter MR, et al. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages. Am J Physiol 2006 Jul; 291(1): L46–57Google Scholar
  66. 66.
    Niewoehner DE, Kleinerman J, Rice DB. Pathologic changes in the peripheral airways of young cigarette smokers. N Engl J Med 1974 Oct 10; 291(15): 755–8PubMedCrossRefGoogle Scholar
  67. 67.
    Ryu JH, Colby TV, Hartman TE, et al. Smoking-related interstitial lung diseases: a concise review. Eur Respir J 2001 Jan; 17(1): 122–32PubMedCrossRefGoogle Scholar
  68. 68.
    Mavridou D, Laws D. Respiratory bronchiolitis associated interstitial lung disease (RB-ILD): a case of an acute presentation. Thorax 2004 Oct; 59(10): 910–1PubMedCrossRefGoogle Scholar
  69. 69.
    Hartman TE, Tazelaar HD, Swensen SJ, et al. Cigarette smoking: CT and pathologic findings of associated pulmonary diseases. Radiographics 1997 Mar–Apr; 17(2): 377–90PubMedGoogle Scholar
  70. 70.
    Aubry MC, Wright JL, Myers JL. The pathology of smokingrelated lung diseases. Clin Chest Med 2000 Mar; 21(1): 11–35,viiPubMedCrossRefGoogle Scholar
  71. 71.
    Wells AU, Nicholson AG, Hansell DM, et al. Respiratory bronchiolitis-associated interstitial lung disease. Semin Respir Crit Care Med 2003 Oct; 24(5): 585–94PubMedCrossRefGoogle Scholar
  72. 72.
    Liebow AA, Steer A, Billingsley JG. Desquamative interstitial pneumonia. Am J Med 1965 Sep; 39: 369–404PubMedCrossRefGoogle Scholar
  73. 73.
    Iskandar SB, McKinney LA, Shah L, et al. Desquamative interstitial pneumonia and hepatitis C virus infection: a rare association. South Med J 2004 Sep; 97(9): 890–3PubMedCrossRefGoogle Scholar
  74. 74.
    Flores-Franco RA, Luevano-Flores E, Gaston-Ramirez C. Sirolimus-associated desquamative interstitial pneumonia. Respiration 2007; 74(2): 237–8PubMedCrossRefGoogle Scholar
  75. 75.
    Hansell DM, Nicholson AG. Smoking-related diffuse parenchymal lung disease: HRCT-pathologic correlation. Semin Respir Crit Care Med 2003 Aug; 24(4): 377–92PubMedCrossRefGoogle Scholar
  76. 76.
    Heyneman LE, Ward S, Lynch DA, et al. Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? Am J Roentgenol 1999 Dec; 173(6): 1617–22Google Scholar
  77. 77.
    Mueller-Mang C, Grosse C, Schmid K, et al. What every radiologist should know about idiopathic interstitial pneumonias. Radiographics 2007 May–Jun; 27(3): 595–615PubMedCrossRefGoogle Scholar
  78. 78.
    Nagai S, Hoshino Y, Hayashi M, et al. Smoking-related interstitial lung diseases. Curr Opin Pulm Med 2000 Sep; 6(5): 415–9PubMedCrossRefGoogle Scholar
  79. 79.
    Matsuo K, Tada S, Kataoka M, et al. Spontaneous remission of desquamative interstitial pneumonia. Intern Med 1997 Oct; 36(10): 728–31PubMedCrossRefGoogle Scholar
  80. 80.
    Patchefsky AS, Fraimow W, Hoch WS. Desquamative interstitial pneumonia. Pathological findings and follow-up in 13 patients. Arch Intern Med 1973 Aug; 132(2): 222–5PubMedCrossRefGoogle Scholar
  81. 81.
    Flusser G, Gurman G, Zirkin H, et al. Desquamative interstitial pneumonitis causing acute respiratory failure, responsive only to immunosuppressants. Respiration 1991; 58(5-6): 324–6PubMedCrossRefGoogle Scholar
  82. 82.
    Verleden GM, Sels F, Van Raemdonck D, et al. Possible recurrence of desquamative interstitial pneumonitis in a single lung transplant recipient. Eur Respir J 1998 Apr; 11(4): 971–4PubMedCrossRefGoogle Scholar
  83. 83.
    Vassallo R, Ryu JH, Colby TV, et al. Pulmonary Langerhans’ cell histiocytosis. N Engl J Med 2000 Jun 29; 342(26): 1969–78PubMedCrossRefGoogle Scholar
  84. 84.
    Tazi A. Adult pulmonary Langerhans’ cell histiocytosis. Eur Respir J 2006 Jun; 27(6): 1272–85PubMedCrossRefGoogle Scholar
  85. 85.
    Yousem SA, Colby TV, Chen YY, et al. Pulmonary Langerhans’ cell histiocytosis: molecular analysis of clonality. Am J Surg Pathol 2001 May; 25(5): 630–6PubMedCrossRefGoogle Scholar
  86. 86.
    Favara BE, Feller AC, Pauli M, et al. Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/ Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol 1997 Sep; 29(3): 157–66PubMedCrossRefGoogle Scholar
  87. 87.
    Vassallo R, Ryu JH. Pulmonary Langerhans’ cell histiocytosis. Clin Chest Med 2004 Sep; 25(3): 561–71, viiPubMedCrossRefGoogle Scholar
  88. 88.
    Arnett NL, Schulz DM. Primary pulmonary eosinophilic granuloma. Radiology 1957 Aug; 69(2): 224–30PubMedGoogle Scholar
  89. 89.
    Lewis JG. Eosinophilic granuloma and its variants with special reference to lung involvement, a report of 12 patients. Q J Med 1964 Jul; 33: 337–59PubMedGoogle Scholar
  90. 90.
    Lewis JG. Pulmonary manifestations of histiocytosis X. Proc R Soc Med 1971 Apr; 64(4): 338–40PubMedGoogle Scholar
  91. 91.
    Smith M, McCormack LJ, Van Ordstrand HS, et al. “Primary” pulmonary histiocytosis X. Chest 1974 Feb; 65(2): 176–80PubMedCrossRefGoogle Scholar
  92. 92.
    Chaowalit N, Pellikka PA, Decker PA, et al. Echocardiographic and clinical characteristics of pulmonary hypertension complicating pulmonary Langerhans cell histiocytosis. Mayo Clin Proc 2004; 79(10): 1269–75PubMedCrossRefGoogle Scholar
  93. 93.
    Aguayo SM, King Jr TE, Waldron Jr JA, et al. Increased pulmonary neuroendocrine cells with bombesin-like immunoreactivity in adult patients with eosinophilic granuloma. J Clin Invest 1990 Sep; 86(3): 838–44PubMedCrossRefGoogle Scholar
  94. 94.
    Asakura S, Colby TV, Limper AH. Tissue localization of transforming growth factor-betal in pulmonary eosinophilic granuloma. Am J Respir Crit Care Med 1996 Nov; 154(5): 1525–30PubMedGoogle Scholar
  95. 95.
    Mendez JL, Nadrous HF, Vassallo R, et al. Pneumothorax in pulmonary Langerhans cell histiocytosis. Chest 2004 Mar; 125(3): 1028–32PubMedCrossRefGoogle Scholar
  96. 96.
    Crausman RS, Jennings CA, Tuder RM, et al. Pulmonary histiocytosis X: pulmonary function and exercise pathophysiology. Am J Respir Crit Care Med 1996 Jan; 153(1): 426–35PubMedGoogle Scholar
  97. 97.
    Moore AD, Godwin JD, Muller NL, et al. Pulmonary histiocytosis X: comparison of radiographic and CT findings. Radiology 1989 Jul; 172(1): 249–54PubMedGoogle Scholar
  98. 98.
    Brauner MW, Grenier P, Mouelhi MM, et al. Pulmonary histiocytosis X: evaluation with high-resolution CT. Radiology 1989 Jul; 172(1): 255–8PubMedGoogle Scholar
  99. 99.
    Brauner MW, Grenier P, Tijani K, et al. Pulmonary Langerhans cell histiocytosis: evolution of lesions on CT scans. Radiology 1997 Aug; 204(2): 497–502PubMedGoogle Scholar
  100. 100.
    Soler P, Chollet S, Jacque C, et al. Immunocytochemical characterization of pulmonary histiocytosis X cells in lung biopsies. Am J Pathol 1985 Mar; 118(3): 439–51PubMedGoogle Scholar
  101. 101.
    Chollet S, Soler P, Bernaudin JF, et al. Exploratory bronchoalveolar lavage [in French]. Presse Med 1984 Jun 9; 13(24): 1503–8PubMedGoogle Scholar
  102. 102.
    Chollet S, Soler P, Dournovo P, et al. Diagnosis of pulmonary histiocytosis X by immunodetection of Langerhans cells in bronchoalveolar lavage fluid. Am J Pathol 1984 May; 115(2): 225–32PubMedGoogle Scholar
  103. 103.
    Fartoukh M, Humbert M, Capron F, et al. Severe pulmonary hypertension in histiocytosis X. Am J Respir Crit Care Med 2000 Jan; 161(1): 216–23PubMedGoogle Scholar
  104. 104.
    Negrin-Dastis S, Butenda D, Dorzee J, et al. Complete disappearance of lung abnormalities on high-resolution computed tomography: a case of histiocytosis X. Can Respir J 2007 May–Jun; 14(4): 235–7PubMedGoogle Scholar
  105. 105.
    Aerni MR, Aubry MC, Myers JL, et al. Complete remission of nodular pulmonary Langerhans cell histiocytosis lesions induced by 2-chlorodeoxyadenosine in a non-smoker. Respir Med 2008 Feb; 102(2): 316–9PubMedCrossRefGoogle Scholar
  106. 106.
    Pardanani A, Phyliky RL, Li CY, et al. 2-Chlorodeoxyadenosine therapy for disseminated Langerhans cell histiocytosis. Mayo Clin Proc 2003 Mar; 78(3): 301–6PubMedCrossRefGoogle Scholar
  107. 107.
    Saleem I, Moss J, Egan JJ. Lung transplantation for rare pulmonary diseases. Sarcoidosis Vasc Diffuse Lung Dis 2005 Dec; 22 Suppl. 1: S85–90PubMedGoogle Scholar
  108. 108.
    Yokoyama A, Mizushima Y, Suzuki H, et al. Acute eosinophilic pneumonia induced by minocycline: prominent Kerley B lines as a feature of positive re-challenge test. Jpn J Med 1990 Mar–Apr; 29(2): 195–8PubMedCrossRefGoogle Scholar
  109. 109.
    Barnes MT, Bascunana J, Garcia B, et al. Acute eosinophilic pneumonia associated with antidepressant agents. Pharm World Sci 1999 Oct; 21(5): 241–2PubMedCrossRefGoogle Scholar
  110. 110.
    Noh H, Lee YK, Kan SW, et al. Acute eosinophilic pneumonia associated with amitriptyline in a hemodialysis patient. Yonsei Med J 2001 Jun; 42(3): 357–9PubMedGoogle Scholar
  111. 111.
    McCormick M, Nelson T. Cocaine-induced fatal acute eosinophilic pneumonia: a case report. WMJ 2007 Apr; 106(2): 92–5PubMedGoogle Scholar
  112. 112.
    Rom WN, Weiden M, Garcia R, et al. Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. Am J Respir Crit Care Med 2002 Sep 15; 166(6): 797–800PubMedCrossRefGoogle Scholar
  113. 113.
    Takizawa H. Acute eosinophilic pneumonia: possible role of hyperreactivity of airway epithelial cells. Intern Med 2002 Nov; 41(11): 917PubMedCrossRefGoogle Scholar
  114. 114.
    Glazer CS, Cohen LB, Schwarz MI. Acute eosinophilic pneumonia in AIDS. Chest 2001 Nov; 120(5): 1732–5PubMedCrossRefGoogle Scholar
  115. 115.
    Hirai K, Yamazaki Y, Okada K, et al. Acute eosinophilic pneumonia associated with smoke from fireworks. Intern Med 2000 May; 39(5): 401–3PubMedCrossRefGoogle Scholar
  116. 116.
    Johkoh T, Muller NL, Akira M, et al. Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients. Radiology 2000 Sep; 216(3): 773–80PubMedGoogle Scholar
  117. 117.
    Allen J. Acute eosinophilic pneumonia. Semin Respir Crit Care Med 2006 Apr; 27(2): 142–7PubMedCrossRefGoogle Scholar
  118. 118.
    Fujimura M, Yasui M, Shinagawa S, et al. Bronchoalveolar lavage cell findings in three types of eosinophilic pneumonia: acute, chronic and drug-induced eosinophilic pneumonia. Respir Med 1998 May; 92(5): 743–9PubMedCrossRefGoogle Scholar
  119. 119.
    Oshikawa K, Kuroiwa K, Tokunaga T, et al. Acute eosinophilic pneumonia with increased soluble ST2 in serum and bronchoalveolar lavage fluid. Respir Med 2001 Jun; 95(6): 532–3PubMedCrossRefGoogle Scholar
  120. 120.
    Daimon T, Tajima S, Oshikawa K, et al. KL-6 and surfactant proteins A and D in serum and bronchoalveolar lavage fluid in patients with acute eosinophilic pneumonia. Intern Med 2005 Aug; 44(8): 811–7PubMedCrossRefGoogle Scholar
  121. 121.
    Jeong YJ, Kim KI, Seo IJ, et al. Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview. Radiographics 2007 May–Jun; 27(3): 617–37PubMedCrossRefGoogle Scholar
  122. 122.
    Ricker DH, Taylor SR, Gartner Jr JC, et al. Fatal pulmonary aspergillosis presenting as acute eosinophilic pneumonia in a previously healthy child. Chest 1991 Sep; 100(3): 875–7PubMedCrossRefGoogle Scholar
  123. 123.
    Buddharaju VL, Saraceno JL, Rosen JM, et al. Acute eosinophilic pneumonia associated with shock. Crit Care Med 1999 Sep; 27(9): 2014–6PubMedCrossRefGoogle Scholar
  124. 124.
    Philit F, Etienne-Mastroianni B, Parrot A, et al. Idiopathic acute eosinophilic pneumonia: a study of 22 patients. Am J Respir Crit Care Med 2002 Nov 1; 166(9): 1235–9PubMedCrossRefGoogle Scholar
  125. 125.
    Benz K, Amann K, Dittrich K, et al. Patient with antibodynegative relapse of Goodpasture syndrome. Clin Nephrol 2007 Apr; 67(4): 240–4PubMedGoogle Scholar
  126. 126.
    Flaherty KR, Martinez FJ. Cigarette smoking in interstitial lung disease: concepts for the internist. Med Clin North Am 2004 Nov; 88(6): 1643–53, xiiiPubMedCrossRefGoogle Scholar
  127. 127.
    King Jr TE, Tooze JA, Schwarz MI, et al. Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model. Am J Respir Crit Care Med 2001; 164(7): 1171–81PubMedGoogle Scholar
  128. 128.
    Antoniou KM, Hansell DM, Rubens MB, et al. Idiopathic pulmonary fibrosis: outcome in relation to smoking status. Am J Respir Crit Care Med 2008 Jan 15; 177(2): 190–4PubMedCrossRefGoogle Scholar
  129. 129.
    Arima K, Ando M, Ito K, et al. Effect of cigarette smoking on prevalence of summer-type hypersensitivity pneumonitis caused by Trichosporon cutaneum. Arch Environ Health 1992 Jul–Aug; 47(4): 274–8PubMedCrossRefGoogle Scholar
  130. 130.
    Depierre A, Dalphin JC, Pernet D, et al. Epidemiological study of farmer’s lung in five districts of the French Doubs province. Thorax 1988 Jun; 43(6): 429–35PubMedCrossRefGoogle Scholar
  131. 131.
    Chang JC, Distler SG, Kaplan AM. Tobacco smoke suppresses T cells but not antigen-presenting cells in the lung-associated lymph nodes. Toxicol Appl Pharmacol1990 Mar 1; 102(3): 514–23PubMedCrossRefGoogle Scholar
  132. 132.
    Ohtsuka Y, Munakata M, Tanimura K, et al. Smoking promotes insidious and chronic farmer’s lung disease, and deteriorates the clinical outcome. Intern Med 1995 Oct; 34(10): 966–71PubMedCrossRefGoogle Scholar
  133. 133.
    Newman LS, Rose CS, Bresnitz EA, et al. A case control etiologic study of sarcoidosis: environmental and occupational risk factors. Am J Respir Crit Care Med 2004 Dec 15; 170(12): 1324–30PubMedCrossRefGoogle Scholar
  134. 134.
    Coates R, Neville E. The development of airways obstruction in sarcoidosis among smokers and non-smokers. Sarcoidosis 1993 Sep; 10(2): 115–7PubMedGoogle Scholar
  135. 135.
    den Boon S, van Lill SW, Borgdorff MW, et al. Association between smoking and tuberculosis infection: a population survey in a high tuberculosis incidence area. Thorax 2005 Jul; 60(7): 555–7CrossRefGoogle Scholar
  136. 136.
    Ariyothai N, Podhipak A, Akarasewi P, et al. Cigarette smoking and its relation to pulmonary tuberculosis in adults. Southeast Asian J Trop Med Public Health 2004 Mar; 35(1): 219–27PubMedGoogle Scholar
  137. 137.
    Kolappan C, Gopi PG. Tobacco smoking and pulmonary tuberculosis. Thorax 2002 Nov; 57(11): 964–6PubMedCrossRefGoogle Scholar
  138. 138.
    Guidon G, BoisclairD. Past, current and future trends in tobacco use. Health nutrition and population discussion paper, World Bank Human Development Network, 2003 [online]. Available from URL: http://siteresources.worldbank.org/HEALTHNUTRITIONANDPOPULATION/Resources/281627-1095698140167/Guindon-PastCurrent-whole.pdf [Accessed 2008 Jun18]

Copyright information

© Adis Data Information BV 2008

Authors and Affiliations

  • Rajesh R. Patel
    • 1
  • Jay H. Ryu
    • 1
  • Robert Vassallo
    • 1
  1. 1.Division of Pulmonary and Critical Care Medicine, Mayo ClinicRochesterUSA

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